4F32

Crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase II from Burkholderia vietnamiensis in complex with platencin

Summary for 4F32

• Entry DOI: 10.2210/pdb4f32/pdb
• Related: 4ddo
• Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, Unknown peptide, 2,4-dihydroxy-3-({3-[(2S,4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid, ... (5 entities in total)
• Functional Keywords: ssgcid, 3-oxoacyl-[acyl-carrier-protein] synthase ii, platencin, structural genomics, seattle structural genomics center for infectious disease, transferase-antibiotic complex, transferase/antibiotic
• Biological source: Burkholderia vietnamiensis; More
• Total number of polymer chains: 3
• Total formula weight: 94856.04

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2012-05-08, release date: 2012-05-23, Last modification date: 2014-02-12)

• Primary citation: Baugh, L.,Gallagher, L.A.,Patrapuvich, R.,Clifton, M.C.,Gardberg, A.S.,Edwards, T.E.,Armour, B.,Begley, D.W.,Dieterich, S.H.,Dranow, D.M.,Abendroth, J.,Fairman, J.W.,Fox, D.,Staker, B.L.,Phan, I.,Gillespie, A.,Choi, R.,Nakazawa-Hewitt, S.,Nguyen, M.T.,Napuli, A.,Barrett, L.,Buchko, G.W.,Stacy, R.,Myler, P.J.,Stewart, L.J.,Manoil, C.,Van Voorhis, W.C.; Combining functional and structural genomics to sample the essential Burkholderia structome.; Plos One, 8:e53851-e53851, 2013; PubMed: 23382856; DOI: 10.1371/journal.pone.0053851

Experimental method

X-RAY DIFFRACTION (1.9 Å)