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PDB: 407 results

1CWC
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IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Improved Binding Affinity for Cyclophilin a by a Cyclosporin Derivative Singly Modified at its Effector Domain.
J.Med.Chem., 37, 1994
1C5F
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CRYSTAL STRUCTURE OF THE CYCLOPHILIN-LIKE DOMAIN FROM BRUGIA MALAYI COMPLEXED WITH CYCLOSPORIN A
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 1
Authors:Ellis, P.J, Carlow, C.K.S, Ma, D, Kuhn, P.
Deposit date:1999-11-22
Release date:1999-12-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Crystal Structure of the Complex of Brugia Malayi Cyclophilin and Cyclosporin A.
Biochemistry, 39, 2000
1AWQ
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CYPA COMPLEXED WITH HAGPIA (PSEUDO-SYMMETRIC MONOMER)
Descriptor: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
Authors:Vajdos, F.F.
Deposit date:1997-10-04
Release date:1998-03-18
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1CWJ
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HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-S-METHYL-SARCOSINE CYCLOSPORIN
Descriptor: CYCLOSPORIN D, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
Deposit date:1998-05-25
Release date:1998-08-26
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1AWT
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SECYPA COMPLEXED WITH HAGPIA
Descriptor: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
Authors:Vajdos, F.F.
Deposit date:1997-10-05
Release date:1998-03-18
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1AWS
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SECYPA COMPLEXED WITH HAGPIA (PSEUDO-SYMMETRIC MONOMER)
Descriptor: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
Authors:Vajdos, F.F.
Deposit date:1997-10-04
Release date:1998-03-18
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1CWB
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THE X-RAY STRUCTURE OF (MEBM2T)1-CYCLOSPORIN COMPLEXED WITH CYCLOPHILIN A PROVIDES AN EXPLANATION FOR ITS ANOMALOUSLY HIGH IMMUNOSUPPRESSIVE ACTIVITY
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V, Kallen, J, Walkinshaw, M.D.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The X-Ray Structure of (Mebm2T)1-Cyclosporin Complexed with Cyclophilin a Provides an Explanation for its Anomalously High Immunosuppressive Activity.
Protein Eng., 7, 1994
1CWM
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HUMAN CYCLOPHILIN A COMPLEXED WITH 4 MEILE CYCLOSPORIN
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
Deposit date:1998-05-26
Release date:1998-07-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWI
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HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-(N-METHYL)-D-ALANINE CYCLOSPORIN
Descriptor: CYCLOSPORIN D, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
Deposit date:1998-05-25
Release date:1998-08-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1AWU
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CYPA COMPLEXED WITH HVGPIA (PSEUDO-SYMMETRIC MONOMER)
Descriptor: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
Authors:Vajdos, F.F.
Deposit date:1997-10-05
Release date:1998-03-18
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1CWH
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HUMAN CYCLOPHILIN A COMPLEXED WITH 3-D-SER CYCLOSPORIN
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
Deposit date:1998-05-07
Release date:1998-07-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWK
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HUMAN CYCLOPHILIN A COMPLEXED WITH 1-(6,7-DIHYDRO)MEBMT 2-VAL 3-D-(2-S-METHYL)SARCOSINE CYCLOSPORIN
Descriptor: CYCLOSPORIN D, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
Deposit date:1998-05-26
Release date:1998-07-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWL
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HUMAN CYCLOPHILIN A COMPLEXED WITH 4 4-HYDROXY-MELEU CYCLOSPORIN
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
Deposit date:1998-05-26
Release date:1998-07-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CWO
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HUMAN CYCLOPHILIN A COMPLEXED WITH THR2, LEU5, D-HIV8, LEU10 CYCLOSPORIN
Descriptor: CYCLOSPORIN C, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
Deposit date:1998-06-05
Release date:1998-08-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Conformational Differences of an Immunosuppressant Peptolide in a Single Crystal and in a Crystal Complex with Human Cyclophilin A.
J.Mol.Biol., 283, 1998
1BCK
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HUMAN CYCLOPHILIN A COMPLEXED WITH 2-THR CYCLOSPORIN
Descriptor: CYCLOSPORIN C, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
Deposit date:1998-04-30
Release date:1998-09-16
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1DYW
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Biochemical and structural characterization of a divergent loop cyclophilin from Caenorhabditis elegans
Descriptor: CYCLOPHILIN 3
Authors:Dornan, J, Page, A.P, Taylor, P, Wu, S.Y, Winter, A.D, Husi, H, Walkinshaw, M.D.
Deposit date:2000-02-10
Release date:2000-06-22
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biochemical and Structural Characterization of a Divergent Loop Cyclophilin from Caenorhabditis Elegans
J.Biol.Chem., 274, 1999
1E3B
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CYCLOPHILIN 3 FROM C.ELEGANS COMPLEXED WITH AUP(ET)3
Descriptor: CYCLOPHILIN 3, GOLD ION, TRIETHYLPHOSPHANE
Authors:Zou, J, Taylor, P, Dornan, J, Robinson, S.P, Walkinshaw, M.D, Sadler, P.J.
Deposit date:2000-06-08
Release date:2000-10-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:First Crystal Structure of a Medicinally Relevant Gold Protein Complex:Unexpected Binding of [Au(Pet (3))](+) to Histidine
Angew.Chem.Int.Ed.Engl., 39, 2000
1AWR
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CYPA COMPLEXED WITH HAGPIA
Descriptor: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
Authors:Vajdos, F.F.
Deposit date:1997-10-04
Release date:1998-03-18
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1AWV
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CYPA COMPLEXED WITH HVGPIA
Descriptor: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
Authors:Vajdos, F.F.
Deposit date:1997-10-05
Release date:1998-03-18
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1AK4
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HUMAN CYCLOPHILIN A BOUND TO THE AMINO-TERMINAL DOMAIN OF HIV-1 CAPSID
Descriptor: CYCLOPHILIN A, HIV-1 CAPSID
Authors:Hill, C.P, Gamble, T.R, Vajdos, F.F, Worthylake, D.K, Sundquist, W.I.
Deposit date:1997-05-28
Release date:1997-10-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid.
Cell(Cambridge,Mass.), 87, 1996
1A58
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CYCLOPHILIN FROM BRUGIA MALAYI
Descriptor: CYCLOPHILIN
Authors:Taylor, P, Page, A.P, Kontopidis, G, Husi, H, Walkinshaw, M.D.
Deposit date:1998-02-20
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The X-ray structure of a divergent cyclophilin from the nematode parasite Brugia malayi.
FEBS Lett., 425, 1998
1E8K
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Cyclophilin 3 Complexed With Dipeptide Ala-Pro
Descriptor: ALANINE, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 3, PROLINE
Authors:Wu, S.Y, Dornan, J, Kontopidis, G, Taylor, P, Walkinshaw, M.D.
Deposit date:2000-09-25
Release date:2001-09-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The First Direct Determination of a Ligand Binding Constant in Protein Crystals
Angew.Chem.Int.Ed.Engl., 40, 2001
1CYN
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CYCLOPHILIN B COMPLEXED WITH [D-(CHOLINYLESTER)SER8]-CYCLOSPORIN
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B
Authors:Mikol, V, Kallen, J, Walkinshaw, M.D.
Deposit date:1995-05-22
Release date:1996-01-29
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-Ray Structure of a Cyclophilin B/Cyclosporin Complex: Comparison with Cyclophilin a and Delineation of its Calcineurin-Binding Domain.
Proc.Natl.Acad.Sci.USA, 91, 1994
5FJB
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Cyclophilin A Stabilize HIV-1 Capsid through a Novel Non- canonical Binding Site
Descriptor: GAG POLYPROTEIN, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Liu, C, Perilla, J.R, Ning, J, Lu, M, Hou, G, Ramalhu, R, Bedwell, G.J, Ahn, J, Shi, J, Gronenborn, A.M, Prevelige Jr, P.E, Rousso, I, Aiken, C, Polenova, T, Schulten, K, Zhang, P.
Deposit date:2015-10-07
Release date:2016-03-16
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cyclophilin a Stabilizes the HIV-1 Capsid Through a Novel Non-Canonical Binding Site.
Nat.Commun., 7, 2016
1MZW
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Crystal structure of a U4/U6 snRNP complex between human spliceosomal cyclophilin H and a U4/U6-60K peptide
Descriptor: U-snRNP-associated cyclophilin, U4/U6 snrnp 60kDa protein
Authors:Reidt, U, Wahl, M.C, Horowitz, D.S, Luehrmann, R, Ficner, R.
Deposit date:2002-10-10
Release date:2003-08-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide
J.Mol.Biol., 331, 2003

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