1MZW

Crystal structure of a U4/U6 snRNP complex between human spliceosomal cyclophilin H and a U4/U6-60K peptide

Summary for 1MZW

• Entry DOI: 10.2210/pdb1mzw/pdb
• Related: 1QOI
• Descriptor: U-snRNP-associated cyclophilin, U4/U6 snrnp 60kDa protein (3 entities in total)
• Functional Keywords: cyclophilin, peptidyl-prolyl-cis/trans isomerase, spliceosome, snrnp, u4/u6-60k protein, wd protein, isomerase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus speckle: O43447; Nucleus speckle (By similarity): O43172
• Total number of polymer chains: 2
• Total formula weight: 22728.16

Authors

Reidt, U.,Wahl, M.C.,Horowitz, D.S.,Luehrmann, R.,Ficner, R. (deposition date: 2002-10-10, release date: 2003-08-19, Last modification date: 2024-02-14)

• Primary citation: Reidt, U.,Wahl, M.C.,Fasshauer, D.,Horowitz, D.S.,Luehrmann, R.,Ficner, R.; Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide; J.Mol.Biol., 331:45-56, 2003; PubMed: 12875835; DOI: 10.1016/S0022-2836(03)00684-3

Experimental method

X-RAY DIFFRACTION (2 Å)