1IKQ
| Pseudomonas Aeruginosa Exotoxin A, wild type | Descriptor: | CHLORIDE ION, EXOTOXIN A, SODIUM ION | Authors: | McKay, D.B, Wedekind, J.E, Trame, C.B. | Deposit date: | 2001-05-04 | Release date: | 2001-12-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Refined Crystallographic Structure of Pseudomonas aeruginosa Exotoxin A
and its Implications for the Molecular Mechanism of Toxicity J.Mol.Biol., 314, 2001
|
|
4G6R
| Minimal Hairpin Ribozyme in the Transition State with G8I Variation | Descriptor: | Loop A Ribozyme strand, Loop A Substrate strand, Loop B Ribozyme Strand, ... | Authors: | Liberman, J.A, Jenkins, J.L, Krucinska, J, Wedekind, J.E. | Deposit date: | 2012-07-19 | Release date: | 2012-08-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.832 Å) | Cite: | A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis. J.Am.Chem.Soc., 134, 2012
|
|
4G6P
| Minimal Hairpin Ribozyme in the Precatalytic State with A38P Variation | Descriptor: | COBALT HEXAMMINE(III), Loop A Substrate strand, Loop A and Loop B Ribozyme strand, ... | Authors: | Liberman, J.A, Jenkins, J.L, Krucinska, J, Wedekind, J.E. | Deposit date: | 2012-07-19 | Release date: | 2012-08-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.641 Å) | Cite: | A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis. J.Am.Chem.Soc., 134, 2012
|
|
4G6S
| Minimal Hairpin Ribozyme in the Transition State with A38P Variation | Descriptor: | COBALT HEXAMMINE(III), Loop A Substrate strand, Loop A and Loop B Ribozyme strand, ... | Authors: | Liberman, J.A, Jenkins, J.L, Krucinska, J, Wedekind, J.E. | Deposit date: | 2012-07-19 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis. J.Am.Chem.Soc., 134, 2012
|
|
4FXW
| Structure of phosphorylated SF1 complex with U2AF65-UHM domain | Descriptor: | SULFATE ION, Splicing factor 1, Splicing factor U2AF 65 kDa subunit | Authors: | Wang, W, Bauer, W.J, Wedekind, J.E, Kielkopf, C.L. | Deposit date: | 2012-07-03 | Release date: | 2013-01-16 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013
|
|
6XH1
| |
6XH0
| |
6XH3
| |
6XH2
| |
6XKN
| |
6XKO
| |
1X7D
| Crystal Structure Analysis of Ornithine Cyclodeaminase Complexed with NAD and ornithine to 1.6 Angstroms | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, L-ornithine, ... | Authors: | Alam, S, Goodman, J.L, Wang, S, Ruzicka, F.J, Frey, P.A, Wedekind, J.E. | Deposit date: | 2004-08-13 | Release date: | 2004-11-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Ornithine Cyclodeaminase: Structure, Mechanism of Action, and Implications for
the u-Crystallin Family Biochemistry, 43, 2004
|
|
3B5A
| Crystal Structure of a Minimally Hinged Hairpin Ribozyme Incorporating A38G mutation with a 2'OMe modification at the active site | Descriptor: | 29-mer Loop A and Loop B Ribozyme strand, COBALT HEXAMMINE(III), Loop A Substrate strand, ... | Authors: | MacElrevey, C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2007-10-25 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
|
|
3B5F
| Crystal Structure of a Minimally Hinged Hairpin Ribozyme Incorporating the Ade38Dap Mutation and a 2',5' Phosphodiester Linkage at the Active Site | Descriptor: | 29-mer Loop A and Loop B Ribozyme strand, COBALT HEXAMMINE(III), Loop A Substrate strand, ... | Authors: | MacElrevey, C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2007-10-25 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
|
|
3BBK
| Miminally Junctioned Hairpin Ribozyme Incorporates A38C and 2'5'-phosphodiester Linkage within Active Site | Descriptor: | COBALT HEXAMMINE(III), Loop A Substrate strand, Loop A and Loop B Ribozyme strand, ... | Authors: | MacElrevey, C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2007-11-09 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
|
|
3BBI
| Minimally Junctioned Hairpin Ribozyme Incorporating A38(2AP) and A-1 2'-O-Me Modifications near Active Site | Descriptor: | COBALT HEXAMMINE(III), Loop A Substrate strand, Loop A and Loop B Ribozyme strand, ... | Authors: | MacElrevey, C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2007-11-09 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
|
|
3BBM
| Minimally Junctioned Hairpin Ribozyme Incorporates A38C and 2'O-Me Modification at Active Site | Descriptor: | COBALT HEXAMMINE(III), Loop A Substrate strand, Loop A and Loop B Ribozyme strand, ... | Authors: | MacElrevey, C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2007-11-09 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
|
|
3B58
| Minimally Junctioned Hairpin Ribozyme Incorporates A38G Mutation and a 2',5'-Phosphodiester Linkage at the Active Site | Descriptor: | 29-mer Loop A and Loop B Ribozyme strand, COBALT HEXAMMINE(III), Loop A Substrate strand, ... | Authors: | MacElrevey, C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2007-10-25 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
|
|
3B91
| Minimally Hinged Hairpin Ribozyme Incorporates Ade38(2AP) and 2',5'-Phosphodiester Linkage Mutations at the Active Site | Descriptor: | 29-mer Loop A and Loop B Ribozyme strand, COBALT HEXAMMINE(III), Loop A Substrate strand, ... | Authors: | MacElrevey, C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2007-11-02 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
|
|
3B5S
| Minimally Hinged Hairpin Ribozyme Incorporates A38DAP Mutation and 2'-O-methyl Modification at the Active Site | Descriptor: | 29-mer Loop A and Loop B Ribozyme strand, COBALT HEXAMMINE(III), Loop A Substrate strand, ... | Authors: | MacElrevey, C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2007-10-26 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
|
|
3CR1
| crystal structure of a minimal, mutant, all-RNA hairpin ribozyme (A38C, A-1OMA) grown from MgCl2 | Descriptor: | MAGNESIUM ION, RNA (5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3'), RNA (5'-R(*UP*CP*GP*UP*GP*GP*UP*CP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'), ... | Authors: | Salter, J.D, Wedekind, J.E. | Deposit date: | 2008-04-04 | Release date: | 2008-08-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme. Rna, 14, 2008
|
|
3CQS
| A 3'-OH, 2',5'-phosphodiester substitution in the hairpin ribozyme active site reveals similarities with protein ribonucleases | Descriptor: | 13-mer substrate strand with 3'-OH, 2',5'-phosphodiester covalently linking 5th and 6th nucleotides, 19-mer ribozyme strand, ... | Authors: | Torelli, A.T, Spitale, R.C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2008-04-03 | Release date: | 2008-05-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Shared traits on the reaction coordinates of ribonuclease and an RNA enzyme Biochem.Biophys.Res.Commun., 371, 2008
|
|
3GCA
| |
3GS8
| An all-RNA hairpin ribozyme A38N1dA38 variant with a transition-state mimic substrate strand | Descriptor: | 2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHYL DIHYDROGEN PHOSPHATE, COBALT HEXAMMINE(III), RNA (5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3'), ... | Authors: | Spitale, R.C, Volpini, R, Heller, M.G, Krucinska, J, Cristalli, G, Wedekind, J.E. | Deposit date: | 2009-03-26 | Release date: | 2009-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Identification of an imino group indispensable for cleavage by a small ribozyme. J.Am.Chem.Soc., 131, 2009
|
|
3GS1
| An all-RNA Hairpin Ribozyme with mutation A38N1dA | Descriptor: | 2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHYL DIHYDROGEN PHOSPHATE, COBALT HEXAMMINE(III), RNA (5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3'), ... | Authors: | Spitale, R.C, Volpini, R, Heller, M.G, Krucinska, J, Cristalli, G, Wedekind, J.E. | Deposit date: | 2009-03-26 | Release date: | 2009-05-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Identification of an imino group indispensable for cleavage by a small ribozyme. J.Am.Chem.Soc., 131, 2009
|
|