1CDJ
| STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 | Descriptor: | T-CELL SURFACE GLYCOPROTEIN CD4 | Authors: | Wu, H, Myszka, D, Tendian, S.W, Brouillette, C.G, Sweet, R.W, Chaiken, I.M, Hendrickson, W.A. | Deposit date: | 1996-11-11 | Release date: | 1997-04-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding. Proc.Natl.Acad.Sci.USA, 93, 1996
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8ERT
| NLRP3 PYD filament | Descriptor: | NACHT, LRR and PYD domains-containing protein 3 | Authors: | Wu, H, Xiao, L. | Deposit date: | 2022-10-12 | Release date: | 2022-12-14 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of the active NLRP3 inflammasome disc. Nature, 613, 2023
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1DS9
| SOLUTION STRUCTURE OF CHLAMYDOMONAS OUTER ARM DYNEIN LIGHT CHAIN 1 | Descriptor: | OUTER ARM DYNEIN | Authors: | Wu, H.W, Maciejewski, M.W, Marintchev, A, Benashski, S.E, Mullen, G.P, King, S.M. | Deposit date: | 2000-01-07 | Release date: | 2000-07-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of a dynein motor domain associated light chain. Nat.Struct.Biol., 7, 2000
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2CAS
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2ZXB
| alpha-L-fucosidase complexed with inhibitor, ph-6FNJ | Descriptor: | (2S,3R,4S,5R)-2-benzylpiperidine-3,4,5-triol, Alpha-L-fucosidase, putative | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | Deposit date: | 2008-12-22 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
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2ZXA
| alpha-L-fucosidase complexed with inhibitor, FNJ-acetyl | Descriptor: | Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}acetamide | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | Deposit date: | 2008-12-22 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
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2ZX5
| alpha-L-fucosidase complexed with inhibitor, F10 | Descriptor: | 3-(1H-indol-3-yl)-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}propanamide, Alpha-L-fucosidase, putative | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | Deposit date: | 2008-12-19 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
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2ZXD
| alpha-L-fucosidase complexed with inhibitor, iso-6FNJ | Descriptor: | (2S,3R,4S,5R)-2-(1-methylethyl)piperidine-3,4,5-triol, Alpha-L-fucosidase, putative | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | Deposit date: | 2008-12-22 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
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2ZWZ
| alpha-L-fucosidase complexed with inhibitor, Core1 | Descriptor: | (2R,3R,4R,5R,6S)-2-(aminomethyl)-6-methylpiperidine-3,4,5-triol, Alpha-L-fucosidase, putative | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | Deposit date: | 2008-12-19 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
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2ZX7
| alpha-L-fucosidase complexed with inhibitor, F10-2C | Descriptor: | Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1H-indole-2-carboxamide | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | Deposit date: | 2008-12-19 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
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2ZX8
| alpha-L-fucosidase complexed with inhibitor, F10-2C-O | Descriptor: | Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1-benzofuran-2-carboxamide | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | Deposit date: | 2008-12-19 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
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2ZX9
| alpha-L-fucosidase complexed with inhibitor, B4 | Descriptor: | (2S)-2-cyclopentyl-2-phenyl-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}ethanamide, Alpha-L-fucosidase, putative | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | Deposit date: | 2008-12-22 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
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2ZX6
| alpha-L-fucosidase complexed with inhibitor, F10-1C | Descriptor: | 2-(1H-indol-3-yl)-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}acetamide, Alpha-L-fucosidase, putative | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | Deposit date: | 2008-12-19 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
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6B17
| Design of a short thermally stable alpha-helix embedded in a macrocycle | Descriptor: | 3,3'-dimethyl-1,1'-biphenyl, Capped-strapped peptide | Authors: | Wu, H, Acharyya, A, Wu, Y, Liu, L, Jo, H, Gai, F, DeGrado, W.F. | Deposit date: | 2017-09-17 | Release date: | 2018-02-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Design of a Short Thermally Stable alpha-Helix Embedded in a Macrocycle. Chembiochem, 19, 2018
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3VA4
| Crystal structure of the mammalian MDC1 FHA domain complexed with CHK2 pThr68 peptide | Descriptor: | Mediator of DNA damage checkpoint protein 1, Serine/threonine-protein kinase Chk2 | Authors: | Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D. | Deposit date: | 2011-12-28 | Release date: | 2012-02-01 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68. Biochemistry, 2012
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3VA1
| Crystal structure of the mammalian MDC1 FHA domain | Descriptor: | Mediator of DNA damage checkpoint protein 1, SULFATE ION | Authors: | Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D. | Deposit date: | 2011-12-28 | Release date: | 2012-02-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68. Biochemistry, 2012
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1HCN
| STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN AT 2.6 ANGSTROMS RESOLUTION FROM MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HUMAN CHORIONIC GONADOTROPIN | Authors: | Wu, H, Lustbader, J.W, Liu, Y, Canfield, R.E, Hendrickson, W.A. | Deposit date: | 1994-07-01 | Release date: | 1994-09-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of human chorionic gonadotropin at 2.6 A resolution from MAD analysis of the selenomethionyl protein. Structure, 2, 1994
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1FB9
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6ANF
| Design of a short thermo-stable alpha-helix embedded in a macrocycle | Descriptor: | 3,3'-dimethyl-1,1'-biphenyl, Capped-strapped peptide | Authors: | Wu, H, Acharyya, A, Wu, Y, Liu, L, Jo, H, Gai, F, DeGrado, W.F. | Deposit date: | 2017-08-13 | Release date: | 2018-02-21 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Design of a Short Thermally Stable alpha-Helix Embedded in a Macrocycle. Chembiochem, 19, 2018
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6R2M
| Crystal structure of PssZ from Listeria monocytogenes | Descriptor: | Glycoside transferase | Authors: | Wu, H, Cheng, J, Qiao, S, Li, D, Ma, L. | Deposit date: | 2019-03-18 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.617 Å) | Cite: | Crystal structure of the glycoside hydrolase PssZ from Listeria monocytogenes. Acta Crystallogr.,Sect.F, 75, 2019
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2ZWY
| alpha-L-fucosidase | Descriptor: | Alpha-L-fucosidase, putative | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | Deposit date: | 2008-12-18 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Basis of alpha-Fucosidase Inhibition by Iminocyclitols with Ki Ranging from Micro- to Picomolar To be Published
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1PVZ
| Solution Structure of BmP07, A Novel Potassium Channel Blocker from Scorpion Buthus martensi Karsch, 15 structures | Descriptor: | K+ toxin-like peptide | Authors: | Wu, H, Zhang, N, Wang, Y, Zhang, Q, Ou, L, Li, M, Hu, G. | Deposit date: | 2003-06-29 | Release date: | 2004-05-18 | Last modified: | 2018-06-20 | Method: | SOLUTION NMR | Cite: | Solution structure of BmKK2, a new potassium channel blocker from the venom of chinese scorpion Buthus martensi Karsch PROTEINS, 55, 2004
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1M9L
| Relaxation-based Refined Structure Of Chlamydomonas Outer Arm Dynein Light Chain 1 | Descriptor: | Outer Arm Dynein Light Chain 1 | Authors: | Wu, H.W, Maciejewski, M.W, Marintchev, A, Benashski, S.E, Mullen, G.P, King, S.M. | Deposit date: | 2002-07-29 | Release date: | 2003-03-04 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Relaxation-based structure refinement and backbone molecular dynamics of the
Dynein motor domain-associated light chain Biochemistry, 42, 2003
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1WM8
| Solution Structure of BmP03 from the Venom of Scorpion Buthus martensii Karsch, 10 structures | Descriptor: | Neurotoxin BmP03 | Authors: | Wu, H, He, F, Li, Y, Wu, G, Cao, C, Chen, X. | Deposit date: | 2004-07-05 | Release date: | 2004-07-27 | Last modified: | 2018-04-18 | Method: | SOLUTION NMR | Cite: | Three-Dimensional Structure of BmP03 from Venom of Scorpion Buthus martensii Karsch Acta Chim.Sinica, 58, 2000
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1WWN
| NMR Solution Structure of BmK-betaIT, an Excitatory Scorpion Toxin from Buthus martensi Karsch | Descriptor: | Excitatory insect selective toxin 1 | Authors: | Wu, H, Tong, X, Chen, X, Zhang, Q, Zheng, X, Zhang, N, Wu, G. | Deposit date: | 2005-01-10 | Release date: | 2006-01-17 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | NMR solution structure of BmK-betaIT, an excitatory scorpion beta-toxin without a 'hot spot' at the relevant position Biochem.Biophys.Res.Commun., 349, 2006
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