8FYR
| MicroED structure of Proteinase K from oxygen milled lamellae | Descriptor: | CALCIUM ION, NITRATE ION, Proteinase K | Authors: | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | Deposit date: | 2023-01-26 | Release date: | 2023-03-08 | Method: | ELECTRON CRYSTALLOGRAPHY (1.5 Å) | Cite: | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals. Nat Commun, 14, 2023
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8FYQ
| MicroED structure of Proteinase K from argon milled lamellae | Descriptor: | CALCIUM ION, NITRATE ION, Proteinase K | Authors: | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | Deposit date: | 2023-01-26 | Release date: | 2023-03-08 | Method: | ELECTRON CRYSTALLOGRAPHY (1.4 Å) | Cite: | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals. Nat Commun, 14, 2023
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8FYN
| MicroED structure of A2A from plasma milled lamellae | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, ... | Authors: | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | Deposit date: | 2023-01-26 | Release date: | 2023-03-08 | Last modified: | 2023-03-22 | Method: | ELECTRON CRYSTALLOGRAPHY (2 Å) | Cite: | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals. Nat Commun, 14, 2023
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8FYS
| MicroED structure of Proteinase K from nitrogen milled lamellae | Descriptor: | CALCIUM ION, Proteinase K | Authors: | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | Deposit date: | 2023-01-26 | Release date: | 2023-03-08 | Method: | ELECTRON CRYSTALLOGRAPHY (1.8 Å) | Cite: | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals. Nat Commun, 14, 2023
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8FYO
| MicroED structure of Proteinase K from lamellae milled from multiple plasma sources | Descriptor: | CALCIUM ION, NITRATE ION, Proteinase K | Authors: | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | Deposit date: | 2023-01-26 | Release date: | 2023-05-24 | Method: | ELECTRON CRYSTALLOGRAPHY (1.39 Å) | Cite: | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals. Nat Commun, 14, 2023
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5J6A
| Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS46 | Descriptor: | (3S)-3-amino-4-[4-({2-[(2,4-dihydroxyphenyl)sulfonyl]-2H-isoindol-5-yl}amino)piperidin-1-yl]-4-oxobutanamide, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | Authors: | Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Wynn, R.M, Chuang, D.T. | Deposit date: | 2016-04-04 | Release date: | 2017-01-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.045 Å) | Cite: | Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors. J. Med. Chem., 60, 2017
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1PFL
| REFINED SOLUTION STRUCTURE OF HUMAN PROFILIN I | Descriptor: | PROFILIN I | Authors: | Metzler, W.J, Farmer II, B.T, Constantine, K.L, Friedrichs, M.S, Lavoie, T, Mueller, L. | Deposit date: | 1994-12-12 | Release date: | 1995-03-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Refined solution structure of human profilin I. Protein Sci., 4, 1995
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1SAN
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1Z1D
| Structural Model for the interaction between RPA32 C-terminal domain and SV40 T antigen origin binding domain. | Descriptor: | Large T antigen, Replication protein A 32 kDa subunit | Authors: | Arunkumar, A.I, Klimovich, V, Jiang, X, Ott, R.D, Mizoue, L, Fanning, E, Chazin, W.J. | Deposit date: | 2005-03-03 | Release date: | 2005-05-17 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisome. Nat.Struct.Mol.Biol., 12, 2005
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2AAK
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2X2S
| Crystal structure of Sclerotinia sclerotiorum agglutinin SSA | Descriptor: | AGGLUTININ, GLYCEROL | Authors: | Sulzenbacher, G, Roig-Zamboni, V, Peumans, W.J, Rouge, P, Van Damme, E.J.M, Bourne, Y. | Deposit date: | 2010-01-15 | Release date: | 2010-05-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of the Galnac/Gal-Specific Agglutinin from the Phytopathogenic Ascomycete Sclerotinia Sclerotiorum Reveals Novel Adaptation of a Beta-Trefoil Domain J.Mol.Biol., 400, 2010
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2WK3
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2XIM
| ARGININE RESIDUES AS STABILIZING ELEMENTS IN PROTEINS | Descriptor: | D-XYLOSE ISOMERASE, MAGNESIUM ION, Xylitol | Authors: | Mrabet, N.T, Van Denbroek, A, Van Den Brande, I, Stanssens, P, Laroche, Y, Lambeir, A.-M, Matthyssens, G, Jenkins, J, Chiadmi, M, Vantilbeurgh, H, Rey, F, Janin, J, Quax, W.J, Lasters, I, Demaeyer, M, Wodak, S.J. | Deposit date: | 1991-05-29 | Release date: | 1993-04-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Arginine residues as stabilizing elements in proteins. Biochemistry, 31, 1992
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1FNZ
| A bark lectin from robinia pseudoacacia in complex with N-acetylgalactosamine | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, BARK AGGLUTININ I, POLYPEPTIDE A, ... | Authors: | Rabijns, A, Verboven, C, Rouge, P, Barre, A, Van Damme, E.J, Peumans, W.J, De Ranter, C.J. | Deposit date: | 2000-08-24 | Release date: | 2001-08-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of a legume lectin from the bark of Robinia pseudoacacia and its complex with N-acetylgalactosamine Proteins, 44, 2001
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1AHD
| DETERMINATION OF THE NMR SOLUTION STRUCTURE OF AN ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX | Descriptor: | DNA (5'-D(*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), Homeotic protein antennapedia | Authors: | Billeter, M, Qian, Y.Q, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K. | Deposit date: | 1993-04-02 | Release date: | 1993-10-31 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex. J.Mol.Biol., 234, 1993
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1FNY
| LEGUME LECTIN OF THE BARK OF ROBINIA PSEUDOACACIA. | Descriptor: | BARK AGGLUTININ I,POLYPEPTIDE A, CALCIUM ION | Authors: | Rabijns, A, Verboven, C, Rouge, P, Barre, A, Van Damme, E.J, Peumans, W.J, De Ranter, C.J. | Deposit date: | 2000-08-24 | Release date: | 2001-08-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structure of a legume lectin from the bark of Robinia pseudoacacia and its complex with N-acetylgalactosamine. Proteins, 44, 2001
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2XCZ
| Crystal Structure of macrophage migration inhibitory factor homologue from Prochlorococcus marinus | Descriptor: | DI(HYDROXYETHYL)ETHER, POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN | Authors: | Wasiel, A.A, Rozeboom, H.J, Hauke, D, Baas, B.J, Zandvoort, E, Quax, W.J, Thunnissen, A.M.W.H, Poelarends, G.J. | Deposit date: | 2010-04-27 | Release date: | 2010-09-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural and Functional Characterization of a Macrophage Migration Inhibitory Factor Homologue from the Marine Cyanobacterium Prochlorococcus Marinus. Biochemistry, 49, 2010
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1HV2
| SOLUTION STRUCTURE OF YEAST ELONGIN C IN COMPLEX WITH A VON HIPPEL-LINDAU PEPTIDE | Descriptor: | ELONGIN C, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR | Authors: | Botuyan, M.V, Mer, G, Yi, G.-S, Koth, C.M, Case, D.A, Edwards, A.M, Chazin, W.J, Arrowsmith, C.H. | Deposit date: | 2001-01-05 | Release date: | 2001-09-06 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide. J.Mol.Biol., 312, 2001
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3BCT
| THE ARMADILLO REPEAT REGION FROM MURINE BETA-CATENIN | Descriptor: | BETA-CATENIN, CHLORIDE ION, UREA | Authors: | Huber, A.H, Nelson, W.J, Weis, W.I. | Deposit date: | 1997-07-31 | Release date: | 1997-11-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three-dimensional structure of the armadillo repeat region of beta-catenin. Cell(Cambridge,Mass.), 90, 1997
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3BKC
| Crystal structure of anti-amyloid beta FAB WO2 (P21, FormB) | Descriptor: | SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | Authors: | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | Deposit date: | 2007-12-06 | Release date: | 2008-04-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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3BOA
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3BKJ
| Crystal structure of Fab wo2 bound to the n terminal domain of amyloid beta peptide (1-16) | Descriptor: | Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | Authors: | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | Deposit date: | 2007-12-06 | Release date: | 2008-04-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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3BKM
| Structure of anti-amyloid-beta Fab WO2 (Form A, P212121) | Descriptor: | SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa, ... | Authors: | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | Deposit date: | 2007-12-07 | Release date: | 2008-04-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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3C7Q
| Structure of VEGFR2 kinase domain in complex with BIBF1120 | Descriptor: | SULFATE ION, Vascular endothelial growth factor receptor 2, methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylate | Authors: | Hilberg, F, Roth, G.J, Krssak, M, Kautschitsch, S, Sommergruber, W, Tontsch-Grunt, U, Garin-Chesa, P, Bader, G, Zoephel, A, Quant, J, Heckel, A, Rettig, W.J. | Deposit date: | 2008-02-08 | Release date: | 2008-12-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy. Cancer Res., 68, 2008
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8PDI
| The phosphatase and C2 domains of SHIP1 with covalent Z1763271112 | Descriptor: | (5-phenyl-1,3,4-thiadiazol-2-yl)methanimine, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | Authors: | Bradshaw, W.J, Moreira, T, Pascoa, T.C, Bountra, C, Chalk, R, von Delft, F, Brennan, P.E, Gileadi, O. | Deposit date: | 2023-06-12 | Release date: | 2023-07-26 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 32, 2024
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