2OJL
| Crystal structure of Q7WAF1_BORPA from Bordetella parapertussis. Northeast Structural Genomics target BpR68. | Descriptor: | Hypothetical protein | Authors: | Benach, J, Neely, H, Seetharaman, J, Wang, H, Fang, Y, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-01-12 | Release date: | 2007-01-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of Q7WAF1_BORPA from Bordetella parapertussis To be Published
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2O0P
| X-ray Crystal Structure of Protein CC0527 (V27M / L66M double mutant) from Caulobacter crescentus. Northeast Structural Genomics Consortium Target CcR55. | Descriptor: | Hypothetical protein CC0527 | Authors: | Seetharaman, J, Su, M, Wang, D, Fang, Y, Cunningham, K, Ma, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-11-27 | Release date: | 2006-12-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Hypothetical Protein from Caulobacter Crescentus. TO BE PUBLISHED
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2OOE
| Crystal structure of HAT domain of murine CstF-77 | Descriptor: | Cleavage stimulation factor 77 kDa subunit | Authors: | Bai, Y, Auperin, T.C, Chou, C.-Y, Chang, G.-G, Manley, J.L, Tong, L. | Deposit date: | 2007-01-25 | Release date: | 2007-04-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors. Mol.Cell, 25, 2007
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2OND
| Crystal Structure of the HAT-C domain of murine CstF-77 | Descriptor: | Cleavage stimulation factor 77 kDa subunit | Authors: | Bai, Y, Auperin, T.C, Chou, C.-Y, Chang, G.-G, Manley, J.L, Tong, L. | Deposit date: | 2007-01-23 | Release date: | 2007-04-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Murine CstF-77: Dimeric Association and Implications for Polyadenylation of mRNA Precursors. Mol.Cell, 25, 2007
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4HNU
| crystal structure of K442E mutant of S. aureus Pyruvate carboxylase | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Yu, L.P.C, Tong, L. | Deposit date: | 2012-10-21 | Release date: | 2013-01-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Characterizing the Importance of the Biotin Carboxylase Domain Dimer for Staphylococcus aureus Pyruvate Carboxylase Catalysis. Biochemistry, 52, 2013
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2OYR
| Crystal Structure of UPF0341 Protein (yhiQ) from Shigella flexneri in complex with S-Adenosyl Homocysteine, Northeast Structural Genomics Target SfR275 | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, UPF0341 protein yhiQ | Authors: | Forouhar, F, Su, M, Seetharaman, J, Janjua, H, Fang, Y, Xiao, R, Baran, M.C, Liu, J, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-02-22 | Release date: | 2007-03-06 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of UPF0341 Protein (yhiQ) from Shigella flexneri in complex with S-Adenosyl Homocysteine, Northeast Structural Genomics Target SfR275 To be Published
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1JQ6
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4ILS
| Crystal structure of engineered protein. northeast structural genomics Consortium target or117 | Descriptor: | Engineered protein | Authors: | Seetharaman, J, Lew, S, Nivon, L, Baker, D, Bjelic, S, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-12-31 | Release date: | 2013-03-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of engineered protein. northeast structural genomics Consortium target or117 To be Published
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5TJB
| I-II linker of TRPML1 channel at pH 4.5 | Descriptor: | Mucolipin-1 | Authors: | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | Deposit date: | 2016-10-04 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nat. Struct. Mol. Biol., 24, 2017
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2QLV
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5TJA
| I-II linker of TRPML1 channel at pH 6 | Descriptor: | Mucolipin-1 | Authors: | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | Deposit date: | 2016-10-04 | Release date: | 2017-01-25 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nat. Struct. Mol. Biol., 24, 2017
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5TJC
| I-II linker of TRPML1 channel at pH 7.5 | Descriptor: | Mucolipin-1 | Authors: | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | Deposit date: | 2016-10-04 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nat. Struct. Mol. Biol., 24, 2017
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5UC8
| Crystal structure of human Heme Oxygenase-2 | Descriptor: | Heme oxygenase 2 | Authors: | Luo, S, Tong, L. | Deposit date: | 2016-12-22 | Release date: | 2017-02-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Heme Oxygenase 2 Binds Myristate to Regulate Retrovirus Assembly and TLR4 Signaling. Cell Host Microbe, 21, 2017
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2QS9
| Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978 | Descriptor: | Retinoblastoma-binding protein 9 | Authors: | Vorobiev, S.M, Su, M, Seetharaman, J, Kuzin, A, Chen, C.X, Cunningham, K, Owens, L, Maglaqui, M, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-07-30 | Release date: | 2007-08-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Crystal structure of human retinoblastoma binding protein 9. Proteins, 74, 2008
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1LXJ
| X-RAY STRUCTURE OF YBL001c NORTHEAST STRUCTURAL GENOMICS (NESG) CONSORTIUM TARGET YTYst72 | Descriptor: | HYPOTHETICAL 11.5KDA PROTEIN IN HTB2-NTH2 INTERGENIC REGION, SULFATE ION | Authors: | Tao, X, Khayat, R, Christendat, D, Savchenko, A, Xu, X, Edwards, A, Arrowsmith, C.H, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-06-05 | Release date: | 2003-07-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | CRYSTAL STRUCTURES OF MTH1187 AND ITS YEAST ORTHOLOG YBL001C Proteins, 52, 2003
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1MI1
| Crystal Structure of the PH-BEACH Domain of Human Neurobeachin | Descriptor: | Neurobeachin | Authors: | Jogl, G, Shen, Y, Gebauer, D, Li, J, Wiegmann, K, Kashkar, H, Kroenke, M, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-08-21 | Release date: | 2002-09-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain. EMBO J., 21, 2002
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5U1T
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5U1S
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5UCA
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5UXF
| Crystal Structure of mouse RECON (AKR1C13) in complex with Cyclic di-AMP | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Dihydrodiol dehydrogenase | Authors: | Luo, S, Tong, L. | Deposit date: | 2017-02-22 | Release date: | 2017-04-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-kappa B Activation and Shapes a Proinflammatory Antibacterial State. Immunity, 46, 2017
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5V21
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5ULI
| Crystal Structure of mouse DXO in complex with (3'-NADP)+ and calcium ion | Descriptor: | CALCIUM ION, Decapping and exoribonuclease protein, [[(2R,3S,4R,5R)-5-(3-aminocarbonyl-4H-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | Authors: | Doamekpor, S.K, Tong, L. | Deposit date: | 2017-01-24 | Release date: | 2017-05-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | 5' End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding. Cell, 168, 2017
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1NDF
| Carnitine Acetyltransferase in Complex with Carnitine | Descriptor: | CARNITINE, Carnitine Acetyltransferase | Authors: | Jogl, G, Tong, L. | Deposit date: | 2002-12-09 | Release date: | 2003-01-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Carnitine Acetyltransferase and Implications for the Catalytic Mechanism and Fatty Acid Transport Cell(Cambridge,Mass.), 112, 2003
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1NF0
| Triosephosphate Isomerase in Complex with DHAP | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, triosephosphate isomerase | Authors: | Jogl, G, Rozovsky, S, McDermott, A.E, Tong, L. | Deposit date: | 2002-12-12 | Release date: | 2003-01-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Optimal alignment for enzymatic proton transfer: Structure of the
Michaelis complex of triosephosphate isomerase at 1.2-A resolution Proc.Natl.Acad.Sci.USA, 100, 2003
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1NDI
| Carnitine Acetyltransferase in complex with CoA | Descriptor: | COENZYME A, Carnitine Acetyltransferase | Authors: | Jogl, G, Tong, L. | Deposit date: | 2002-12-09 | Release date: | 2003-01-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Carnitine Acetyltransferase and Implications for the Catalytic Mechanism and Fatty Acid Transport Cell(Cambridge,Mass.), 112, 2003
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