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5TJB

I-II linker of TRPML1 channel at pH 4.5

Summary for 5TJB
Entry DOI10.2210/pdb5tjb/pdb
Related5TJA 5TJC
DescriptorMucolipin-1 (2 entities in total)
Functional Keywordsendolysosomal lumen, tetramer, calcium and ph regulation, transport protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight25195.06
Authors
Li, M.,Zhang, W.K.,Benvin, N.M.,Zhou, X.,Su, D.,Li, H.,Wang, S.,Michailidis, I.E.,Tong, L.,Li, X.,Yang, J. (deposition date: 2016-10-04, release date: 2017-01-25, Last modification date: 2023-10-04)
Primary citationLi, M.,Zhang, W.K.,Benvin, N.M.,Zhou, X.,Su, D.,Li, H.,Wang, S.,Michailidis, I.E.,Tong, L.,Li, X.,Yang, J.
Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel.
Nat. Struct. Mol. Biol., 24:205-213, 2017
Cited by
PubMed: 28112729
DOI: 10.1038/nsmb.3362
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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