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PDB: 2 results

8OIV
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BU of 8oiv by Molmil
Monkeypox virus VP39 in complex with SAH and cap0
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Skvara, P, Chalupska, D, Silhan, J, Klima, M, Boura, E.
Deposit date:2023-03-23
Release date:2023-08-23
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39.
Antiviral Res., 216, 2023
8CGB
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BU of 8cgb by Molmil
Monkeypox virus VP39 in complex with SAH
Descriptor: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Silhan, J, Klima, M, Skvara, P, Boura, E.
Deposit date:2023-02-03
Release date:2023-04-26
Last modified:2023-05-03
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase.
Nat Commun, 14, 2023

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