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PDB: 3 results

5LNF
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BU of 5lnf by Molmil
Solution NMR structure of farnesylated PEX19, C-terminal domain
Descriptor: FARNESYL, Peroxisomal biogenesis factor 19
Authors:Emmanouilidis, L, Schuetz, U, Tripsianes, K, Madl, T, Radke, J, Rucktaeschel, R, Wilmanns, M, Schliebs, W, Erdmann, R, Sattler, M.
Deposit date:2016-08-04
Release date:2017-03-15
Last modified:2019-09-11
Method:SOLUTION NMR
Cite:Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19.
Nat Commun, 8, 2017
6N1T
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BU of 6n1t by Molmil
Toxoplasma gondii TS-DHFR in complex with selective inhibitor 3
Descriptor: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-{4-[3-(2-methoxypyrimidin-5-yl)phenyl]piperazin-1-yl}pyrimidine-2,4-diamine, ...
Authors:Hopper, A.T, Brockman, A, Wise, A, Gould, J, Barks, J, Radke, J.B, Sibley, L.D, Zou, Y, Thomas, S.B.
Deposit date:2018-11-11
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Discovery of Selective Toxoplasma gondii Dihydrofolate Reductase Inhibitors for the Treatment of Toxoplasmosis.
J. Med. Chem., 62, 2019
6N1S
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BU of 6n1s by Molmil
Toxoplasma gondii TS-DHFR in complex with selective inhibitor 29
Descriptor: 1,2-ETHANEDIOL, 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ...
Authors:Hopper, A.T, Brockman, A, Wise, A, Gould, J, Barks, J, Radke, J.B, Sibley, L.D, Zou, Y, Thomas, S.B.
Deposit date:2018-11-11
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Discovery of Selective Toxoplasma gondii Dihydrofolate Reductase Inhibitors for the Treatment of Toxoplasmosis.
J. Med. Chem., 62, 2019

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