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PDB: 41 results

1W9C
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Proteolytic fragment of CRM1 spanning six C-terminal HEAT repeats
Descriptor: CRM1 PROTEIN
Authors:Petosa, C, Schoehn, G, Askjaer, P, Bauer, U, Moulin, M, Steuerwald, U, Soler-Lopez, M, Baudin, F, Mattaj, I.W, Muller, C.W.
Deposit date:2004-10-08
Release date:2004-12-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Architecture of Crm1-Exportin 1 Suggests How Cooperativity is Achieved During Formation of a Nuclear Export Complex
Mol.Cell, 16, 2004
2C9L
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Structure of the Epstein-Barr virus ZEBRA protein
Descriptor: 5'-D(*AP*AP*GP*CP*AP*CP*TP*GP*AP*CP *TP*CP*AP*TP*GP*AP*AP*GP*T)-3', 5'-D(*AP*CP*TP*TP*CP*AP*CP*TP*GP*AP *GP*TP*CP*AP*GP*TP*GP*CP*T)-3', BZLF1 TRANS-ACTIVATOR PROTEIN
Authors:Petosa, C, Morand, P, Baudin, F, Moulin, M, Artero, J.B, Muller, C.W.
Deposit date:2005-12-13
Release date:2006-02-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Basis of Lytic Cycle Activation by the Epstein-Barr Virus Zebra Protein
Mol.Cell, 21, 2006
2C9N
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Structure of the Epstein-Barr virus ZEBRA protein at approximately 3. 5 Angstrom resolution
Descriptor: 5'-D(*CP*AP*CP*TP*GP*AP*CP*TP*CP*AP *T)-3', 5'-D(*CP*AP*TP*GP*AP*GP*TP*CP*AP*GP *T)-3', BZLF1 TRANS-ACTIVATOR PROTEIN
Authors:Petosa, C, Morand, P, Baudin, F, Moulin, M, Artero, J.B, Muller, C.W.
Deposit date:2005-12-13
Release date:2006-02-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Basis of Lytic Cycle Activation by the Epstein-Barr Virus Zebra Protein
Mol.Cell, 21, 2006
8R6K
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Crystal structure of Candida glabrata Bdf1 bromodomain 1 bound to a phenyltriazine ligand
Descriptor: 6-methyl-~{N}-[(5-methylfuran-2-yl)methyl]-3-(4-methylphenyl)-1,2,4-triazin-5-amine, Candida glabrata strain CBS138 chromosome C complete sequence, PHOSPHATE ION, ...
Authors:Petosa, C, Wei, K, McKenna, C.E, Govin, J.
Deposit date:2023-11-22
Release date:2024-10-30
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection
Advanced Science, 2024
8R6I
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Crystal structure of Candida glabrata Bdf1 bromodomain 1 in the unbound state
Descriptor: Candida glabrata strain CBS138 chromosome C complete sequence
Authors:Petosa, C, Wei, K, McKenna, C.E, Govin, J.
Deposit date:2023-11-22
Release date:2024-10-30
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection
Advanced Science, 2024
8R6N
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Crystal structure of Candida glabrata Bdf1 bromodomain 2 bound to a pyridoindole ligand
Descriptor: 2-ethanoyl-~{N}-(4-morpholin-4-ylphenyl)-1,3,4,5-tetrahydropyrido[4,3-b]indole-8-carboxamide, Candida glabrata strain CBS138 chromosome C complete sequence
Authors:Petosa, C, Wei, K, McKenna, C.E, Govin, J.
Deposit date:2023-11-22
Release date:2024-10-30
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection
Advanced Science, 2024
8R6L
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Crystal structure of Candida glabrata Bdf1 bromodomain 2 in the unbound state
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Candida glabrata strain CBS138 chromosome C complete sequence, ...
Authors:Petosa, C, Wei, K, McKenna, C.E, Govin, J.
Deposit date:2023-11-22
Release date:2024-10-30
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection
Advanced Science, 2024
8R6J
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Crystal structure of Candida glabrata Bdf1 bromodomain 1 bound to a pyrazole ligand
Descriptor: 2-methyl-~{N}-[[5-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]methyl]pyrazole-3-carboxamide, Candida glabrata strain CBS138 chromosome C complete sequence, SULFATE ION
Authors:Petosa, C, Wei, K, McKenna, C.E, Govin, J.
Deposit date:2023-11-22
Release date:2024-10-30
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection
Advanced Science, 2024
8R6M
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Crystal structure of Candida glabrata Bdf1 bromodomain 2 bound to I-BET151
Descriptor: 7-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-8-METHOXY-1-[(1R)-1-(PYRIDIN-2-YL)ETHYL]-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-2-ONE, Candida glabrata strain CBS138 chromosome C complete sequence, GLYCEROL, ...
Authors:Petosa, C, Wei, K, McKenna, C.E, Govin, J.
Deposit date:2023-11-22
Release date:2024-10-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection
Advanced Science, 2024
1A37
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14-3-3 PROTEIN ZETA BOUND TO PS-RAF259 PEPTIDE
Descriptor: 14-3-3 PROTEIN ZETA, PS-RAF259 PEPTIDE LSQRQRST(SEP)TPNVHM
Authors:Petosa, C, Masters, S.C, Pohl, J, Wang, B, Fu, H, Liddington, R.C.
Deposit date:1998-01-28
Release date:1999-03-02
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove.
J.Biol.Chem., 273, 1998
1A38
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14-3-3 PROTEIN ZETA BOUND TO R18 PEPTIDE
Descriptor: 14-3-3 PROTEIN ZETA, R18 PEPTIDE (PHCVPRDLSWLDLEANMCLP)
Authors:Petosa, C, Masters, S.C, Pohl, J, Wang, B, Fu, H, Liddington, R.C.
Deposit date:1998-01-28
Release date:1999-03-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove.
J.Biol.Chem., 273, 1998
1ACC
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BU of 1acc by Molmil
ANTHRAX PROTECTIVE ANTIGEN
Descriptor: ANTHRAX PROTECTIVE ANTIGEN, CALCIUM ION
Authors:Petosa, C, Liddington, R.C.
Deposit date:1997-02-05
Release date:1998-02-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the anthrax toxin protective antigen.
Nature, 385, 1997
2PYO
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BU of 2pyo by Molmil
Drosophila nucleosome core
Descriptor: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
Authors:Clapier, C.R, Petosa, C, Mueller, C.W.
Deposit date:2007-05-16
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer.
Proteins, 71, 2007
5LDF
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BU of 5ldf by Molmil
Maltose binding protein genetically fused to dodecameric glutamine synthetase
Descriptor: Glutamine synthetase, Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Coscia, F, Petosa, C, Schoehn, G.
Deposit date:2016-06-25
Release date:2016-08-10
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein.
Sci Rep, 6, 2016
6TEM
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BU of 6tem by Molmil
CENP-A nucleosome core particle with 145 base pairs of the Widom 601 sequence by cryo-EM
Descriptor: Histone H2A, Histone H2B 1.1, Histone H3-like centromeric protein A, ...
Authors:Boopathi, R, Danev, R, Petosa, C, Bednar, J.
Deposit date:2019-11-12
Release date:2020-04-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends.
Nucleic Acids Res., 48, 2020
7ZTK
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BU of 7ztk by Molmil
NME1 in complex with CoA
Descriptor: COENZYME A, Nucleoside diphosphate kinase A
Authors:Garcia-Saez, I, Iuso, D, Khochbin, S, Petosa, C.
Deposit date:2022-05-10
Release date:2023-08-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet.
Sci Adv, 9, 2023
7ZL8
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NME1 in complex with succinyl-CoA
Descriptor: Nucleoside diphosphate kinase A, SUCCINYL-COENZYME A
Authors:Garcia-Saez, I, Iuso, D, Khochbin, S, Petosa, C.
Deposit date:2022-04-14
Release date:2023-08-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet.
Sci Adv, 9, 2023
7ZLW
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NME1 in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase A
Authors:Garcia-Saez, I, Iuso, D, Khochbin, S, Petosa, C.
Deposit date:2022-04-15
Release date:2023-08-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet.
Sci Adv, 9, 2023
6HKT
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Structure of an H1-bound 6-nucleosome array
Descriptor: DNA (1122-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Garcia-Saez, I, Dimitrov, S, Petosa, C.
Deposit date:2018-09-08
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (9.7 Å)
Cite:Structure of an H1-Bound 6-Nucleosome Array Reveals an Untwisted Two-Start Chromatin Fiber Conformation.
Mol. Cell, 72, 2018
7NX5
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BU of 7nx5 by Molmil
Crystal structure of the Epstein-Barr Virus protein ZEBRA (BZLF1, Zta) bound to a methylated DNA duplex
Descriptor: Trans-activator protein BZLF1, meZRE2 DNA (bottom strand), meZRE2 DNA (top strand)
Authors:Bernaudat, F, Petosa, C.
Deposit date:2021-03-17
Release date:2021-12-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of DNA methylation-dependent site selectivity of the Epstein-Barr virus lytic switch protein ZEBRA/Zta/BZLF1.
Nucleic Acids Res., 50, 2022
2WP2
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BU of 2wp2 by Molmil
Structure of Brdt bromodomain BD1 bound to a diacetylated histone H4 peptide.
Descriptor: BROMODOMAIN TESTIS-SPECIFIC PROTEIN, HISTONE H4
Authors:Moriniere, J, Rousseaux, S, Steuerwald, U, Soler-Lopez, M, Curtet, S, Vitte, A.-L, Govin, J, Gaucher, J, Sadoul, K, Hart, D.J, Krijgsveld, J, Khochbin, S, Mueller, C.W, Petosa, C.
Deposit date:2009-08-02
Release date:2009-09-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Cooperative Binding of Two Acetylation Marks on a Histone Tail by a Single Bromodomain.
Nature, 461, 2009
4BSM
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BU of 4bsm by Molmil
Crystal structure of the Nuclear Export Receptor CRM1 (exportin-1) lacking the C-terminal helical extension at 4.5A
Descriptor: EXPORTIN-1
Authors:Dian, C, Bernaudat, F, Langer, K, Oliva, M.F, Fornerod, M, Schoehn, G, Muller, C.W, Petosa, C.
Deposit date:2013-06-10
Release date:2013-07-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix.
Structure, 21, 2013
4BSN
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Crystal structure of the Nuclear Export Receptor CRM1 (exportin-1) lacking the C-terminal helical extension at 4.1A
Descriptor: EXPORTIN-1
Authors:Dian, C, Bernaudat, F, Langer, K, Oliva, M.F, Fornerod, M, Schoehn, G, Muller, C.W, Petosa, C.
Deposit date:2013-06-11
Release date:2013-07-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix.
Structure, 21, 2013
1JKY
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BU of 1jky by Molmil
Crystal Structure of the Anthrax Lethal Factor (LF): Wild-type LF Complexed with the N-terminal Sequence of MAPKK2
Descriptor: Lethal Factor, mitogen-activated protein kinase kinase 2
Authors:Pannifer, A.D, Wong, T.Y, Schwarzenbacher, R, Renatus, M, Petosa, C, Collier, R.J, Bienkowska, J, Lacy, D.B, Park, S, Leppla, S.H, Hanna, P, Liddington, R.C.
Deposit date:2001-07-13
Release date:2001-11-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structure of the anthrax lethal factor.
Nature, 414, 2001
1UUS
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Structure of an activated Dictyostelium STAT in its DNA-unbound form
Descriptor: STAT PROTEIN
Authors:Soler-Lopez, M, Petosa, C, Fukuzawa, M, Ravelli, R, Williams, J.G, Muller, C.W.
Deposit date:2004-01-09
Release date:2004-03-26
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of an Activated Dictyostelium Stat in its DNA-Unbound Form
Mol.Cell, 13, 2004

 

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