4D7Z
 
 | | E. coli L-aspartate-alpha-decarboxylase mutant N72Q to a resolution of 1.9 Angstroms | | Descriptor: | ASPARTATE 1-DECARBOXYLASE ALPHA CHAIN, ASPARTATE 1-DECARBOXYLASE BETA CHAIN, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Bravo, J.P.K, Monteiro, D.C.F, Webb, M.E, Pearson, A.R. | | Deposit date: | 2014-12-02 | | Release date: | 2016-01-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Structure of the E. Coli L-Aspartate-Alpha-Decarboxylase Mutant N72Q to a Resolution of 1.9 Angstroms
To be Published
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5Y17
 | | CATPO mutant - E316F | | Descriptor: | CALCIUM ION, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase | | Authors: | Karakus Yuzugullu, Y, Goc, G, Balci, S, Pearson, A.R, Yorke, B. | | Deposit date: | 2017-07-19 | | Release date: | 2018-07-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Identification of the site of oxidase substrate binding in Scytalidium thermophilum catalase.
Acta Crystallogr D Struct Biol, 74, 2018
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5YEM
 | | CATPO mutant - T188F | | Descriptor: | CALCIUM ION, Catalase, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Yuzugullu Karakus, Y, Balci, S, Goc, G, Pearson, A.R, Yorke, B. | | Deposit date: | 2017-09-18 | | Release date: | 2018-07-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Investigation of how gate residues in the main channel affect the catalytic activity of Scytalidium thermophilum catalase.
Acta Crystallogr D Struct Biol, 80, 2024
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5XY4
 | | CATPO mutant - V536W | | Descriptor: | CALCIUM ION, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase, ... | | Authors: | Yuzugullu Karakus, Y, Goc, G, Balci, S, Pearson, A.R, Yorke, B. | | Deposit date: | 2017-07-06 | | Release date: | 2018-07-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Identification of the site of oxidase substrate binding in Scytalidium thermophilum catalase.
Acta Crystallogr D Struct Biol, 74, 2018
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5ZZ1
 | | Probing the active center of catalase-phenol oxidase from Scytalidium thermophilum | | Descriptor: | 3-AMINO-1,2,4-TRIAZOLE, CALCIUM ION, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, ... | | Authors: | Yuzugullu Karakus, Y, Trinh, C.H, Pearson, A.R, Ogel, Z.B, McPherson, M.J. | | Deposit date: | 2018-05-29 | | Release date: | 2019-05-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Identification of the site of oxidase substrate binding in Scytalidium thermophilum catalase.
Acta Crystallogr D Struct Biol, 74, 2018
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4CRY
 | | Direct visualisation of strain-induced protein post-translational modification | | Descriptor: | ACETYL COENZYME *A, ASPARTATE 1-DECARBOXYLASE, CHLORIDE ION, ... | | Authors: | Monteiro, D.C.F, Patel, V, Bartlett, C.P, Grant, T.D, Nozaki, S, Gowdy, J.A, Snell, E.H, Niki, H, Pearson, A.R, Webb, M.E. | | Deposit date: | 2014-03-02 | | Release date: | 2015-03-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Direct Visualisation of Strain-Induced Protein Post-Translational Modification
To be Published
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5XZM
 | | CATPO mutant - V228I | | Descriptor: | CALCIUM ION, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase, ... | | Authors: | Yuzugullu Karakus, Y, Balci, S, Goc, G, Pearson, A.R, Yorke, B. | | Deposit date: | 2017-07-12 | | Release date: | 2018-07-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | CATPO mutant - V228I
To Be Published
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5XZN
 | | CATPO mutant - V228C | | Descriptor: | CALCIUM ION, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase, ... | | Authors: | Yuzugullu Karakus, Y, Balci, S, Goc, G, Pearson, A.R, Yorke, B. | | Deposit date: | 2017-07-13 | | Release date: | 2018-07-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | CATPO mutant - V228C
To Be Published
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6GRR
 | | Crystal structure of Escherichia coli amine oxidase mutant I342F/E573Q | | Descriptor: | Amine oxidase, CALCIUM ION, COPPER (II) ION, ... | | Authors: | Gaule, T.G, Smith, M.A, Tych, K.M, Pirrat, P, Trinh, C.H, Pearson, A.R, Knowles, P.F, McPherson, M.J. | | Deposit date: | 2018-06-12 | | Release date: | 2018-09-05 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Oxygen Activation Switch in the Copper Amine Oxidase of Escherichia coli.
Biochemistry, 57, 2018
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6RXI
 | | In-flow serial synchrotron crystallography using a 3D-printed microfluidic device (3D-MiXD): Lysozyme | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Lysozyme C, ... | | Authors: | Monteiro, D.C.F, von Stetten, D, Pearson, A.R, Trebbin, M. | | Deposit date: | 2019-06-08 | | Release date: | 2020-03-18 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | 3D-MiXD: 3D-printed X-ray-compatible microfluidic devices for rapid, low-consumption serial synchrotron crystallography data collection in flow.
Iucrj, 7, 2020
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2WNZ
 | | Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate in space group P21 crystal form I | | Descriptor: | (2S)-2-HYDROXYPROPANOIC ACID, 2-ETHOXYETHANOL, LACTIC ACID, ... | | Authors: | Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | | Deposit date: | 2009-07-21 | | Release date: | 2010-08-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
J.Mol.Biol., 404, 2010
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2WKJ
 | | Crystal structure of the E192N mutant of E. Coli N-acetylneuraminic acid lyase in complex with pyruvate at 1.45A resolution in space group P212121 | | Descriptor: | N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL, PYRUVIC ACID | | Authors: | Campeotto, I, Carr, S.B, Trinh, C.H, Nelson, A.S, Berry, A, Phillips, S.E.V, Pearson, A.R. | | Deposit date: | 2009-06-11 | | Release date: | 2009-12-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure of an Escherichia coli N-acetyl-D-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 angstrom resolution.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 65, 2009
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2WNN
 | | Structure of wild type E. coli N-acetylneuraminic acid lyase in complex with pyruvate in space group P21 | | Descriptor: | N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL, SODIUM ION | | Authors: | Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | | Deposit date: | 2009-07-13 | | Release date: | 2010-08-25 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
J.Mol.Biol., 404, 2010
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2WPB
 | | Crystal structure of the E192N mutant of E. Coli N-acetylneuraminic acid lyase in complex with pyruvate and the inhibitor (2R,3R)-2,3,4- trihydroxy-N,N-dipropylbutanamide in space group P21 crystal form I | | Descriptor: | (2R,3R)-2,3,4-TRIHYDROXY-N,N-DIPROPYLBUTANAMIDE, N-ACETYLNEURAMINATE LYASE | | Authors: | Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | | Deposit date: | 2009-08-03 | | Release date: | 2010-08-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
J.Mol.Biol., 404, 2010
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2XFW
 | | Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate in crystal form III | | Descriptor: | N-ACETYLNEURAMINIC ACID LYASE, PENTAETHYLENE GLYCOL, PYRUVIC ACID | | Authors: | Campeotto, I, Murshudov, G.N, Bolt, A.H, Trinh, C.H, Phillips, S.E.V, Nelson, A, Pearson, A.R, Berry, A. | | Deposit date: | 2010-05-28 | | Release date: | 2010-09-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
To be Published
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2YGY
 | | Structure of wild type E. coli N-acetylneuraminic acid lyase in space group P21 crystal form II | | Descriptor: | CHLORIDE ION, N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL | | Authors: | Campeotto, I, Nelson, A, Berry, A, Phillips, S.E.V, Pearson, A.R. | | Deposit date: | 2011-04-23 | | Release date: | 2012-04-04 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Pathological macromolecular crystallographic data affected by twinning, partial-disorder and exhibiting multiple lattices for testing of data processing and refinement tools.
Sci Rep, 8, 2018
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6RXH
 | | In-flow serial synchrotron crystallography using a 3D-printed microfluidic device (3D-MiXD): Aspartate alpha-decarboxylase | | Descriptor: | Aspartate 1-decarboxylase, UNKNOWN ATOM OR ION | | Authors: | Monteiro, D.C.F, von Stetten, D, Pearson, A.R, Trebbin, M. | | Deposit date: | 2019-06-08 | | Release date: | 2020-03-18 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | 3D-MiXD: 3D-printed X-ray-compatible microfluidic devices for rapid, low-consumption serial synchrotron crystallography data collection in flow.
Iucrj, 7, 2020
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4AMA
 | | Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165 in complex with pyruvate | | Descriptor: | N-ACETYLNEURAMINATE LYASE | | Authors: | Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A. | | Deposit date: | 2012-03-08 | | Release date: | 2013-01-23 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural insights into the recovery of aldolase activity in N-acetylneuraminic acid lyase by replacement of the catalytically active lysine with gamma-thialysine by using a chemical mutagenesis strategy.
Chembiochem, 14, 2013
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3ZX8
 | | Cryo-EM reconstruction of native and expanded Turnip Crinkle virus | | Descriptor: | CAPSID PROTEIN | | Authors: | Bakker, S.E, Robottom, J, Hogle, J.M, Maeda, A, Pearson, A.R, Stockley, P.G, Ranson, N.A, Harrison, S.C. | | Deposit date: | 2011-08-08 | | Release date: | 2012-07-18 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (11.5 Å) | | Cite: | Isolation of an Asymmetric RNA Uncoating Intermediate for a Single-Stranded RNA Plant Virus.
J.Mol.Biol., 417, 2012
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3ZX9
 | | Cryo-EM reconstruction of native and expanded Turnip Crinkle virus | | Descriptor: | CAPSID PROTEIN | | Authors: | Bakker, S.E, Robottom, J, Pearson, A.R, Stockley, P.G, Ranson, N.A. | | Deposit date: | 2011-08-08 | | Release date: | 2012-07-18 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (17 Å) | | Cite: | Isolation of an Asymmetric RNA Uncoating Intermediate for a Single-Stranded RNA Plant Virus.
J.Mol.Biol., 417, 2012
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4AH7
 | | Structure of Wild Type Stapylococcus aureus N-acetylneuraminic acid lyase in complex with pyruvate | | Descriptor: | N-ACETYLNEURAMINATE LYASE | | Authors: | Timms, N, Poyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A. | | Deposit date: | 2012-02-03 | | Release date: | 2013-01-23 | | Last modified: | 2013-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
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4AUL
 | | Crystal structure, recombinant expression and mutagenesis studies of the bifunctional catalase-phenol oxidase from Scytalidium thermophilum | | Descriptor: | CALCIUM ION, CATALASE-PHENOL OXIDASE, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Yuzugullu, Y, Trinh, C.H, Smith, M.A, Pearson, A.R, Phillips, S.E.V, Sutay Kocabas, D, Bakir, U, Ogel, Z.B, McPherson, M.J. | | Deposit date: | 2012-05-18 | | Release date: | 2013-02-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure, Recombinant Expression and Mutagenesis Studies of the Catalase with Oxidase Activity from Scytalidium Thermophilum
Acta Crystallogr.,Sect.D, 69, 2013
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4AUM
 | | Crystal structure, recombinant expression and mutagenesis studies of the bifunctional catalase-phenol oxidase from Scytalidium thermophilum | | Descriptor: | CALCIUM ION, CATALASE-PHENOL OXIDASE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, ... | | Authors: | Yuzugullu, Y, Trinh, C.H, Smith, M.A, Pearson, A.R, Phillips, S.E.V, Sutay Kocabas, D, Bakir, U, Ogel, Z.B, McPherson, M.J. | | Deposit date: | 2012-05-18 | | Release date: | 2013-02-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure, Recombinant Expression and Mutagenesis Studies of the Catalase with Oxidase Activity from Scytalidium Thermophilum
Acta Crystallogr.,Sect.D, 69, 2013
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4BCU
 | | Satellite Tobacco Necrosis Virus (STNV) virus like particle in complex with the B3 aptamer | | Descriptor: | CALCIUM ION, COAT PROTEIN | | Authors: | Ford, R.J, Barker, A.M, Bakker, S.E, Coutts, R.H, Ranson, N.A, Phillips, S.E.V, Pearson, A.R, Stockley, P.G. | | Deposit date: | 2012-10-03 | | Release date: | 2013-01-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Sequence-Specific, RNA-Protein Interactions Overcome Electrostatic Barriers Preventing Assembly of Satellite Tobacco Necrosis Virus Coat Protein.
J.Mol.Biol., 425, 2013
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3ZD0
 | | The Solution Structure of Monomeric Hepatitis C Virus p7 Yields Potent Inhibitors of Virion Release | | Descriptor: | P7 PROTEIN | | Authors: | Foster, T.L, Sthompson, G, Kalverda, A.P, Kankanala, J, Thompson, J, Barker, A.M, Clarke, D, Noerenberg, M, Pearson, A.R, Rowlands, D.J, Homans, S.W, Harris, M, Foster, R, Griffin, S.D.C. | | Deposit date: | 2012-11-23 | | Release date: | 2013-09-04 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structure-Guided Design Affirms Inhibitors of Hepatitis C Virus P7 as a Viable Class of Antivirals Targeting Virion Release
Hepatology, 59, 2014
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