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PDB: 64 results

4F3D
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BU of 4f3d by Molmil
Structure of RPE65: P65 crystal form grown in Fos-Choline-10
Descriptor: 2-ETHOXYETHANOL, FE (II) ION, Retinoid isomerohydrolase
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2012-05-09
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F2Z
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BU of 4f2z by Molmil
Crystal structure of RPE65 in a lipid environment
Descriptor: FE (II) ION, Retinoid isomerohydrolase
Authors:Kiser, P.D, Shi, W, Palczewski, K.
Deposit date:2012-05-08
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4CIZ
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BU of 4ciz by Molmil
Crystal structure of the complex of the Cellular Retinal Binding Protein with 9-cis-retinal
Descriptor: L(+)-TARTARIC ACID, RETINAL, RETINALDEHYDE-BINDING PROTEIN 1
Authors:Bolze, C.S, Helbling, R.E, Owen, R.L, Pearson, A.R, Pompidor, G, Dworkowski, F, Fuchs, M.R, Furrer, J, Golczak, M, Palczewski, K, Cascella, M, Stocker, A.
Deposit date:2013-12-18
Release date:2014-01-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.403 Å)
Cite:Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-Cis-Retinal Isomerase Activity.
J.Am.Chem.Soc., 136, 2014
4CJ6
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BU of 4cj6 by Molmil
Crystal structure of the complex of the Cellular Retinal Binding Protein Mutant R234W with 9-cis-retinal
Descriptor: RETINAL, RETINALDEHYDE-BINDING PROTEIN 1
Authors:Bolze, C.S, Helbling, R.E, Owen, R.L, Pearson, A.R, Pompidor, G, Dworkowski, F, Fuchs, M.R, Furrer, J, Golczak, M, Palczewski, K, Cascella, M, Stocker, A.
Deposit date:2013-12-19
Release date:2014-01-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.896 Å)
Cite:Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-Cis-Retinal Isomerase Activity.
J.Am.Chem.Soc., 136, 2014
4DPZ
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BU of 4dpz by Molmil
Crystal structure of human HRASLS2
Descriptor: HRAS-like suppressor 2
Authors:Kiser, P.D, Golczak, M, Sears, A.E, Lodowski, D.T, Palczewski, K.
Deposit date:2012-02-14
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins.
J.Biol.Chem., 287, 2012
4DOT
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BU of 4dot by Molmil
Crystal structure of human HRASLS3.
Descriptor: Group XVI phospholipase A2
Authors:Kiser, P.D, Golczak, M, Sears, A.E, Lodowski, D.T, Palczewski, K.
Deposit date:2012-02-10
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins.
J.Biol.Chem., 287, 2012
4F3J
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BU of 4f3j by Molmil
Crystal Structure of Trimeric gC1q Domain of Human C1QTNF5 associated with Late-onset Retinal Macular Degeneration
Descriptor: Complement C1q tumor necrosis factor-related protein 5
Authors:Tu, X, Palczewski, K.
Deposit date:2012-05-09
Release date:2012-11-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.337 Å)
Cite:Crystal structure of the globular domain of C1QTNF5: Implications for late-onset retinal macular degeneration.
J.Struct.Biol., 180, 2012
4Q95
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BU of 4q95 by Molmil
Crystal structure of HRASLS3/LRAT chimeric protein
Descriptor: HEPTANOIC ACID, HRAS-like suppressor 3, Lecithin retinol acyltransferase
Authors:Golczak, M, Kiser, P.D, Sears, A.E, Palczewski, K.
Deposit date:2014-04-29
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3.
Nat.Chem.Biol., 11, 2015
4Q2R
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BU of 4q2r by Molmil
Structural Proteomics From Crude Native Rod Outer Segments
Descriptor: Creatine kinase B-type, SULFATE ION
Authors:Baker, B.Y, Shi, W, Palczewski, K.
Deposit date:2014-04-09
Release date:2014-09-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Proteomics From Crude Native Rod Outer Segments
To be Published
4RYX
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BU of 4ryx by Molmil
Crystal structure of RPE65 in complex with emixustat and palmitate, P6522 crystal form
Descriptor: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, (4S)-2-METHYL-2,4-PENTANEDIOL, FE (II) ION, ...
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2014-12-17
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
J.Clin.Invest., 125, 2015
4RSE
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BU of 4rse by Molmil
Crystal structure of RPE65 in complex with MB-001 and palmitate
Descriptor: (1R)-3-amino-1-{3-[(2,6,6-trimethylcyclohex-1-en-1-yl)methoxy]phenyl}propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D, Shi, W, Palczewski, K.
Deposit date:2014-11-07
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat.Chem.Biol., 11, 2015
4RYY
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BU of 4ryy by Molmil
Crystal structure of RPE65 in complex with R-emixustat and palmitate
Descriptor: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2014-12-17
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
J.Clin.Invest., 125, 2015
4RYZ
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BU of 4ryz by Molmil
Crystal structure of RPE65 in complex with S-emixustat and palmitate
Descriptor: (1S)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2014-12-17
Release date:2015-05-27
Last modified:2021-07-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
J.Clin.Invest., 125, 2015
4RSC
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BU of 4rsc by Molmil
Crystal structure of RPE65 in complex with emixustat and palmitate
Descriptor: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D, Shi, W, Palczewski, K.
Deposit date:2014-11-07
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat.Chem.Biol., 11, 2015
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