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PDB: 24 results

3UGB
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BU of 3ugb by Molmil
UbcH5c~Ubiquitin Conjugate
Descriptor: GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3
Authors:Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S.
Deposit date:2011-11-02
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates.
Biochemistry, 51, 2012
4GKY
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BU of 4gky by Molmil
Crystal structure of a carbohydrate-binding domain
Descriptor: CALCIUM ION, GLYCEROL, Protein ERGIC-53, ...
Authors:Page, R.C, Zheng, C, Nix, J.C, Misra, S, Zhang, B.
Deposit date:2012-08-13
Release date:2013-06-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4201 Å)
Cite:Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII).
J.Biol.Chem., 288, 2013
4GKX
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BU of 4gkx by Molmil
Crystal structure of a carbohydrate-binding domain
Descriptor: CALCIUM ION, GLYCEROL, Protein ERGIC-53, ...
Authors:Page, R.C, Zheng, C, Nix, J.C, Misra, S, Zhang, B.
Deposit date:2012-08-13
Release date:2013-06-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII).
J.Biol.Chem., 288, 2013
3RGH
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BU of 3rgh by Molmil
Structure of filamin A immunoglobulin-like repeat 10 from Homo sapiens
Descriptor: ACETATE ION, Filamin-A
Authors:Page, R.C, Clark, J, Misra, S.
Deposit date:2011-04-08
Release date:2011-08-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structure of filamin A immunoglobulin-like repeat 10 from Homo sapiens.
Acta Crystallogr.,Sect.F, 67, 2011
3TGD
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BU of 3tgd by Molmil
Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b
Descriptor: Ubiquitin-conjugating enzyme E2 D2
Authors:Page, R.C, Amick, J, Misra, S.
Deposit date:2011-08-17
Release date:2011-08-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b
To be Published
3R6B
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BU of 3r6b by Molmil
Crystal Structure of Thrombospondin-1 TSR Domains 2 and 3
Descriptor: 1,2-ETHANEDIOL, Thrombospondin-1
Authors:Page, R.C, Klenotic, P.A, Misra, S, Silverstein, R.L.
Deposit date:2011-03-21
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.
Protein Expr.Purif., 80, 2011
6OP7
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BU of 6op7 by Molmil
Structure of oxidized VIM-20
Descriptor: ACETATE ION, Metallo-beta-lactamase VIM-20, ZINC ION
Authors:Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C.
Deposit date:2019-04-24
Release date:2019-10-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Mbio, 10, 2019
2K3M
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BU of 2k3m by Molmil
Rv1761c
Descriptor: Rv1761c, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Page, R.C, Moore, J.D, Lee, S, Opella, S.J, Cross, T.A.
Deposit date:2008-05-14
Release date:2009-01-06
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Backbone structure of a small helical integral membrane protein: A unique structural characterization.
Protein Sci., 18, 2009
4KBQ
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BU of 4kbq by Molmil
Structure of the CHIP-TPR domain in complex with the Hsc70 Lid-Tail domains
Descriptor: E3 ubiquitin-protein ligase CHIP, Heat shock cognate 71 kDa protein
Authors:Page, R.C, Amick, J, Nix, J.C, Misra, S.
Deposit date:2013-04-23
Release date:2015-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:A Bipartite Interaction between Hsp70 and CHIP Regulates Ubiquitination of Chaperoned Client Proteins.
Structure, 23, 2015
6CQS
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BU of 6cqs by Molmil
Sediminispirochaeta smaragdinae SPS-1 metallo-beta-lactamase
Descriptor: Beta-lactamase, ZINC ION
Authors:Page, R.C, VanPelt, J, Cheng, Z, Crowder, M.W.
Deposit date:2018-03-16
Release date:2018-08-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Noncanonical Metal Center Drives the Activity of the Sediminispirochaeta smaragdinae Metallo-beta-lactamase SPS-1.
Biochemistry, 57, 2018
6NHK
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BU of 6nhk by Molmil
Mortalin nucleotide binding domain in the ADP-bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Page, R.C, Moseng, M.A, Nix, J.C.
Deposit date:2018-12-23
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.777 Å)
Cite:Biophysical Consequences of EVEN-PLUS Syndrome Mutations for the Function of Mortalin.
J.Phys.Chem.B, 123, 2019
6OP6
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BU of 6op6 by Molmil
Structure of VIM-20 in the reduced state
Descriptor: Metallo-beta-lactamase VIM-20, SODIUM ION, ZINC ION
Authors:Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C.
Deposit date:2019-04-24
Release date:2019-10-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Mbio, 10, 2019
4NQ2
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BU of 4nq2 by Molmil
Structure of Zn(II)-bound metallo-beta-lactamse VIM-2 from Pseudomonas aeruginosa
Descriptor: ACETATE ION, Beta-lactamase class B VIM-2, ZINC ION
Authors:Aitha, M, Nix, J.C, Crowder, M.W, Page, R.C.
Deposit date:2013-11-23
Release date:2014-11-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Biochemical, Mechanistic, and Spectroscopic Characterization of Metallo-beta-lactamase VIM-2.
Biochemistry, 53, 2014
6P2U
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BU of 6p2u by Molmil
Structure of Mortalin-NBD with N6-propargyladenosine-5'-diphosphate
Descriptor: 9-{5-O-[(S)-hydroxy(phosphonooxy)phosphoryl]-alpha-D-ribofuranosyl}-N-(prop-2-yn-1-yl)-9H-purin-6-amine, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Moseng, M.A, Page, R.C.
Deposit date:2019-05-22
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:2- and N6-functionalized adenosine-5'-diphosphate analogs for the inhibition of mortalin.
Febs Lett., 593, 2019
6PMT
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BU of 6pmt by Molmil
Structure of Mortalin-NBD with adenosine-5'-monophosphate and thiodiphosphate
Descriptor: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Stress-70 protein, ...
Authors:Moseng, M.A, Nix, J.C, Page, R.C.
Deposit date:2019-07-02
Release date:2020-07-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the mortalin nucleotide binding domain in complex with adenosine monophosphate
to be published
5F16
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BU of 5f16 by Molmil
CTA-modified hen egg-white lysozyme
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:McGlone, C, Nix, J.C, Page, R.C.
Deposit date:2015-11-30
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme-Polymer Conjugates.
Biomacromolecules, 17, 2016
5F14
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BU of 5f14 by Molmil
Structure of native hen egg-white lysozyme
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:McGlone, C, Nix, J.C, Page, R.C.
Deposit date:2015-11-30
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.148 Å)
Cite:Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme-Polymer Conjugates.
Biomacromolecules, 17, 2016
2KNC
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BU of 2knc by Molmil
Platelet integrin ALFAIIB-BETA3 transmembrane-cytoplasmic heterocomplex
Descriptor: Integrin alpha-IIb, Integrin beta-3
Authors:Yang, J, Ma, Y, Page, R.C, Misra, S, Plow, E.F, Qin, J.
Deposit date:2009-08-20
Release date:2009-09-29
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.
Proc.Natl.Acad.Sci.USA, 106, 2009
8SUV
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BU of 8suv by Molmil
CHIP-TPR in complex with the C-terminus of CHIC2
Descriptor: Cysteine-rich hydrophobic domain-containing protein 2, E3 ubiquitin-protein ligase CHIP, SULFATE ION
Authors:Cupo, A.R, McDermott, L.E, DeSilva, A.R, Callahan, M, Nix, J.C, Gestwicki, J.E, Page, R.C.
Deposit date:2023-05-13
Release date:2024-03-20
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Interaction with the membrane-anchored protein CHIC2 constrains the ubiquitin ligase activity of CHIP
Biorxiv, 2023
5WIH
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BU of 5wih by Molmil
Structure of New Delhi Metallo-Beta-lactamase 12 (NDM-12)
Descriptor: Metallo-beta-lactamase NDM-12, ZINC ION
Authors:VanPelt, J, Williams, C, Page, R.C.
Deposit date:2017-07-19
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Clinical Variants of New Delhi Metallo-beta-Lactamase Are Evolving To Overcome Zinc Scarcity.
Acs Infect Dis., 3, 2017
5WIG
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BU of 5wig by Molmil
Structure of New Delhi Metallo-Beta-lactamase 4 (NDM-4)
Descriptor: NDM-4, ZINC ION
Authors:VanPelt, J, Williams, C, Page, R.C.
Deposit date:2017-07-19
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Clinical Variants of New Delhi Metallo-beta-Lactamase Are Evolving To Overcome Zinc Scarcity.
Acs Infect Dis., 3, 2017
4JS9
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BU of 4js9 by Molmil
Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, Mesoheme, Nitric oxide synthase, ...
Authors:Hannibal, L, Page, R.C, Bolisetty, K, Yu, Z, Misra, S, Stuehr, D.J.
Deposit date:2013-03-22
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.784 Å)
Cite:Kinetic and Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme
To be Published
3DWJ
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BU of 3dwj by Molmil
Heme-proximal W188H mutant of inducible nitric oxide synthase
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, AMMONIUM ION, Nitric oxide synthase, ...
Authors:Tejero, J, Biswas, A, Wang, Z.-Q, Haque, M.M, Hemann, C, Zweier, J.L, Page, R.C, Misra, S, Stuehr, D.J.
Deposit date:2008-07-22
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Stabilization and Characterization of a Heme-Oxy Reaction Intermediate in Inducible Nitric-oxide Synthase
J.Biol.Chem., 283, 2008
4KBO
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BU of 4kbo by Molmil
Crystal structure of the human Mortalin (GRP75) ATPase domain in the apo form
Descriptor: SODIUM ION, Stress-70 protein, mitochondrial
Authors:Amick, J, Page, R.C, Nix, J.C, Misra, S.
Deposit date:2013-04-23
Release date:2014-04-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone.
Protein Sci., 23, 2014

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