2KNC
Platelet integrin ALFAIIB-BETA3 transmembrane-cytoplasmic heterocomplex
Summary for 2KNC
| Entry DOI | 10.2210/pdb2knc/pdb |
| NMR Information | BMRB: 16496 |
| Descriptor | Integrin alpha-IIb, Integrin beta-3 (2 entities in total) |
| Functional Keywords | integrin, transmembrane signaling, protein structure, cell adhesion, cleavage on pair of basic residues, disease mutation, disulfide bond, glycoprotein, membrane, pyrrolidone carboxylic acid, receptor, transmembrane, host-virus interaction, phosphoprotein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 14832.34 |
| Authors | Yang, J.,Ma, Y.,Page, R.C.,Misra, S.,Plow, E.F.,Qin, J. (deposition date: 2009-08-20, release date: 2009-09-29, Last modification date: 2023-06-14) |
| Primary citation | Yang, J.,Ma, Y.Q.,Page, R.C.,Misra, S.,Plow, E.F.,Qin, J. Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation. Proc.Natl.Acad.Sci.USA, 106:17729-17734, 2009 Cited by PubMed: 19805198DOI: 10.1073/pnas.0909589106 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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