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PDB: 129 results

7Z7C
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BU of 7z7c by Molmil
Broadly neutralizing DARPin bnD.8 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BF520)
Descriptor: 1,2-ETHANEDIOL, Broadly neutralizing DARPin bnD.8, Envelope glycoprotein gp160, ...
Authors:Mittl, P.R, Gloegl, M.
Deposit date:2022-03-15
Release date:2023-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
7YWK
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BU of 7ywk by Molmil
Crystal structure of an engineered TycA variant, TycApPLA, in complex with AMP
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
Authors:Mittl, P, Camus, A, Truong, G, Markert, G, Hilvert, D.
Deposit date:2022-02-14
Release date:2022-09-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Reprogramming Nonribosomal Peptide Synthetases for Site-Specific Insertion of alpha-Hydroxy Acids.
J.Am.Chem.Soc., 144, 2022
7YWJ
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BU of 7ywj by Molmil
Crystal structure of an engineered TycA variant, TycA pPLA (L313P)
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ...
Authors:Mittl, P, Camus, A, Truong, G, Markert, G, Hilvert, D.
Deposit date:2022-02-14
Release date:2022-09-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Reprogramming Nonribosomal Peptide Synthetases for Site-Specific Insertion of alpha-Hydroxy Acids.
J.Am.Chem.Soc., 144, 2022
7TBQ
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BU of 7tbq by Molmil
LOV2-DARPIN fusion : D7
Descriptor: CHLORIDE ION, D7 LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, ...
Authors:Mittl, P.
Deposit date:2021-12-22
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.678 Å)
Cite:LOV2-DARPIN fusion : D7
To Be Published
7TAL
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BU of 7tal by Molmil
LOV2-DARPIN fusion : D4_deltaDARP
Descriptor: D4_deltaDARP LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION
Authors:Mittl, P.
Deposit date:2021-12-21
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:LOV2-DARPIN fusion : D4_deltaDARP
To Be Published
7TBO
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BU of 7tbo by Molmil
LOV2-DARPIN fusion : D12
Descriptor: D12 LOV2-DARPin fusion, GLYCEROL
Authors:Mittl, P.
Deposit date:2021-12-22
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:LOV2-DARPIN fusion : D12
To Be Published
6HV2
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BU of 6hv2 by Molmil
MMP-13 in complex with the peptide IMISF
Descriptor: CALCIUM ION, Collagenase 3, GLYCEROL, ...
Authors:Mittl, P, Riedl, R, Hohl, D.
Deposit date:2018-10-10
Release date:2019-01-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.709 Å)
Cite:Drug Design Inspired by Nature: Crystallographic Detection of an Auto-Tailored Protease Inhibitor Template.
Angew.Chem.Int.Ed.Engl., 58, 2019
7TBN
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BU of 7tbn by Molmil
LOV2-DARPIN fusion : D11
Descriptor: CARBONATE ION, D11 LOV2-DARPin fusion, GLYCEROL
Authors:Mittl, P.
Deposit date:2021-12-22
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:LOV2-DARPIN fusion : D11
To Be Published
1GES
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BU of 1ges by Molmil
ANATOMY OF AN ENGINEERED NAD-BINDING SITE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE
Authors:Mittl, P.R.E, Schulz, G.E.
Deposit date:1994-01-18
Release date:1994-11-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Anatomy of an engineered NAD-binding site.
Protein Sci., 3, 1994
1GEU
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BU of 1geu by Molmil
ANATOMY OF AN ENGINEERED NAD-BINDING SITE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Mittl, P.R.E, Schulz, G.E.
Deposit date:1994-01-18
Release date:1994-11-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Anatomy of an engineered NAD-binding site.
Protein Sci., 3, 1994
1GET
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BU of 1get by Molmil
ANATOMY OF AN ENGINEERED NAD-BINDING SITE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Mittl, P.R.E, Schulz, G.E.
Deposit date:1994-01-18
Release date:1994-11-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Anatomy of an engineered NAD-binding site.
Protein Sci., 3, 1994
1TGJ
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BU of 1tgj by Molmil
HUMAN TRANSFORMING GROWTH FACTOR-BETA 3, CRYSTALLIZED FROM DIOXANE
Descriptor: 1,4-DIETHYLENE DIOXIDE, TRANSFORMING GROWTH FACTOR-BETA 3
Authors:Mittl, P.R.E, Priestle, J.P, Gruetter, M.G.
Deposit date:1996-07-09
Release date:1997-01-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
1TGK
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BU of 1tgk by Molmil
HUMAN TRANSFORMING GROWTH FACTOR BETA 3, CRYSTALLIZED FROM PEG 4000
Descriptor: TRANSFORMING GROWTH FACTOR BETA 3
Authors:Mittl, P.R.E, Priestle, J.P, Gruetter, M.G.
Deposit date:1996-07-10
Release date:1997-03-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
7QNL
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BU of 7qnl by Molmil
LOV2-DARPIN FUSION - D4_DeltaLOV
Descriptor: DARPIN, SULFATE ION
Authors:Mittl, P.
Deposit date:2021-12-21
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:LOV2-DARPIN FUSION - D4_DeltaLOV
To Be Published
7TCD
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BU of 7tcd by Molmil
LOV2-DARPIN fusion: D13
Descriptor: CHLORIDE ION, D13 LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, ...
Authors:Mittl, P.
Deposit date:2021-12-23
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:LOV2-DARPIN fusion: D13
To Be Published
1HIA
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BU of 1hia by Molmil
KALLIKREIN COMPLEXED WITH HIRUSTASIN
Descriptor: HIRUSTASIN, KALLIKREIN
Authors:Mittl, P, Di Marco, S, Gruetter, M.
Deposit date:1996-12-12
Release date:1997-12-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A new structural class of serine protease inhibitors revealed by the structure of the hirustasin-kallikrein complex.
Structure, 5, 1997
8A1A
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BU of 8a1a by Molmil
Structure of a leucinostatin derivative determined by host lattice display : L1F11V1 construct
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ...
Authors:Mittl, P.R.E.
Deposit date:2022-06-01
Release date:2022-12-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of a hydrophobic leucinostatin derivative determined by host lattice display.
Acta Crystallogr D Struct Biol, 78, 2022
8A19
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BU of 8a19 by Molmil
Structure of a leucinostatin derivative determined by host lattice display : L1E4V1 construct
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ...
Authors:Mittl, P.R.E.
Deposit date:2022-06-01
Release date:2022-12-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.358 Å)
Cite:Structure of a hydrophobic leucinostatin derivative determined by host lattice display.
Acta Crystallogr D Struct Biol, 78, 2022
8AED
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BU of 8aed by Molmil
Broadly neutralizing DARPin bnD.9 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BG505)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Broadly neutralizing DARPin bnD.9, ...
Authors:Mittl, P, Gloegl, M.
Deposit date:2022-07-13
Release date:2023-08-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
1OUV
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BU of 1ouv by Molmil
Helicobacter cysteine rich protein C (HcpC)
Descriptor: conserved hypothetical secreted protein
Authors:Mittl, P.R, Luethy, L.
Deposit date:2003-03-25
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Helicobacter Cysteine-rich Protein C at 2.0A Resolution: Similar Peptide-binding Sites in TPR and SEL1-like Repeat Proteins
J.Mol.Biol., 340, 2004
1GER
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BU of 1ger by Molmil
THE STRUCTURE OF GLUTATHIONE REDUCTASE FROM ESCHERICHIA COLI AT 1.86 ANGSTROMS RESOLUTION: COMPARISON WITH THE ENZYME FROM HUMAN ERYTHROCYTES
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE
Authors:Mittl, P.R.E, Schulz, G.E.
Deposit date:1994-01-18
Release date:1994-11-01
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure of glutathione reductase from Escherichia coli at 1.86 A resolution: comparison with the enzyme from human erythrocytes.
Protein Sci., 3, 1994
1KSO
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BU of 1kso by Molmil
CRYSTAL STRUCTURE OF APO S100A3
Descriptor: S100 CALCIUM-BINDING PROTEIN A3
Authors:Mittl, P.R, Fritz, G, Sargent, D.F, Richmond, T.J, Heizmann, C.W, Grutter, M.G.
Deposit date:2002-01-14
Release date:2002-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Metal-free MIRAS phasing: structure of apo-S100A3.
Acta Crystallogr.,Sect.D, 58, 2002
1AIE
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BU of 1aie by Molmil
P53 TETRAMERIZATION DOMAIN CRYSTAL STRUCTURE
Descriptor: P53
Authors:Mittl, P.R.E, Chene, P, Gruetter, M.G.
Deposit date:1997-04-17
Release date:1997-06-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystallization and structure solution of p53 (residues 326-356) by molecular replacement using an NMR model as template.
Acta Crystallogr.,Sect.D, 54, 1998
8AH9
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BU of 8ah9 by Molmil
De novo retro-aldolase RAbetaB-16.1
Descriptor: BENZOIC ACID, RAbetaB-16.1
Authors:Mittl, P, Oualb Chaib, A, Hilvert, D.
Deposit date:2022-07-21
Release date:2023-08-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.747 Å)
Cite:Design and optimization of enzymatic activity in a de novo beta-barrel scaffold.
Protein Sci., 31, 2022
7BHF
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BU of 7bhf by Molmil
DARPin_D5/Her3 domain 4 complex, orthorhombic crystals
Descriptor: ACETATE ION, DARPin_D5, Isoform 4 of Receptor tyrosine-protein kinase erbB-3
Authors:Mittl, P.R.E, Radom, F, Pluckthun, A.
Deposit date:2021-01-11
Release date:2021-11-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Crystal structures of HER3 extracellular domain 4 in complex with the designed ankyrin-repeat protein D5.
Acta Crystallogr.,Sect.F, 77, 2021

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