4EYM
 
 | | MAPK13 complex with inhibitor | | Descriptor: | 2-(morpholin-4-yl)-N-[4-(pyridin-4-yloxy)phenyl]pyridine-4-carboxamide, Mitogen-activated protein kinase 13 | | Authors: | Miller, C.A, Brett, T.J. | | Deposit date: | 2012-05-01 | | Release date: | 2012-12-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.353 Å) | | Cite: | IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
J.Clin.Invest., 122, 2012
|
|
4EYJ
 | | MAPK13 Complex with inhibitor | | Descriptor: | 1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-[4-(pyridin-4-yloxy)phenyl]urea, Mitogen-activated protein kinase 13 | | Authors: | Miller, C.A, Brett, T.J. | | Deposit date: | 2012-05-01 | | Release date: | 2012-12-19 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
J.Clin.Invest., 122, 2012
|
|
4YNO
 | |
5FBK
 | | Crystal structure of the extracellular domain of human calcium sensing receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ... | | Authors: | Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J. | | Deposit date: | 2015-12-14 | | Release date: | 2016-06-22 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
|
|
2R9H
 | |
1FY2
 | | Aspartyl Dipeptidase | | Descriptor: | ASPARTYL DIPEPTIDASE, CADMIUM ION | | Authors: | Hakansson, K, Wang, A.H.-J, Miller, C.G. | | Deposit date: | 2000-09-28 | | Release date: | 2001-01-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The structure of aspartyl dipeptidase reveals a unique fold with a Ser-His-Glu catalytic triad.
Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
5KBN
 | | The crystal structure of fluoride channel Fluc Ec2 F80I Mutant | | Descriptor: | DECYL-BETA-D-MALTOPYRANOSIDE, FLUORIDE ION, Putative fluoride ion transporter CrcB, ... | | Authors: | Last, N.B, Kolmakova-Partensky, L, Shane, T, Miller, C. | | Deposit date: | 2016-06-03 | | Release date: | 2016-08-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Mechanistic signs of double-barreled structure in a fluoride ion channel.
Elife, 5, 2016
|
|
1FYE
 | |
5KOM
 | | The crystal structure of fluoride channel Fluc Ec2 F83I Mutant | | Descriptor: | DECYL-BETA-D-MALTOPYRANOSIDE, FLUORIDE ION, Putative fluoride ion transporter CrcB, ... | | Authors: | Last, N.B, Kolmakova-Partensky, L, Shane, T, Miller, C. | | Deposit date: | 2016-06-30 | | Release date: | 2016-08-03 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Mechanistic signs of double-barreled structure in a fluoride ion channel.
Elife, 5, 2016
|
|
1FNO
 | | PEPTIDASE T (TRIPEPTIDASE) | | Descriptor: | PEPTIDASE T, SULFATE ION, ZINC ION | | Authors: | Hakansson, K, Miller, C.G. | | Deposit date: | 2000-08-22 | | Release date: | 2002-03-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of Peptidase T from Salmonella typhimurium
Eur.J.Biochem., 269, 2002
|
|
4ENE
 | | Structure of the N- and C-terminal trimmed ClC-ec1 Cl-/H+ antiporter and Fab Complex | | Descriptor: | CHLORIDE ION, DECYL-BETA-D-MALTOPYRANOSIDE, H(+)/Cl(-) exchange transporter ClcA, ... | | Authors: | Lim, H.H, Shane, T, Miller, C. | | Deposit date: | 2012-04-13 | | Release date: | 2012-12-26 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Intracellular proton access in a cl(-)/h(+) antiporter.
Plos Biol., 10, 2012
|
|
5NKQ
 | | Crystal structure of a dual topology fluoride ion channel. | | Descriptor: | FLUORIDE ION, Monobody, Putative fluoride ion transporter CrcB, ... | | Authors: | Stockbridge, R, Miller, C, Newstead, S. | | Deposit date: | 2017-03-31 | | Release date: | 2017-04-26 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Crystal structures of a double-barrelled fluoride ion channel.
Nature, 525, 2015
|
|
5A43
 | | Crystal structure of a dual topology fluoride ion channel. | | Descriptor: | DECYL-BETA-D-MALTOPYRANOSIDE, FLUORIDE ION, MONOBODIES, ... | | Authors: | Stockbridge, R.B, Kolmakova-Partensky, L, Shane, T, Koide, A, Koide, S, Miller, C, Newstead, S. | | Deposit date: | 2015-06-04 | | Release date: | 2015-09-02 | | Last modified: | 2015-09-30 | | Method: | X-RAY DIFFRACTION (2.58 Å) | | Cite: | Crystal Structures of a Double-Barrelled Fluoride Ion Channel.
Nature, 525, 2015
|
|
5A40
 | | Crystal structure of a dual topology fluoride ion channel. | | Descriptor: | MERCURY (II) ION, MONOBODIES, PUTATIVE FLUORIDE ION TRANSPORTER CRCB | | Authors: | Stockbridge, R.B, Kolmakova-Partensky, L, Shane, T, Koide, A, Koide, S, Miller, C, Newstead, S. | | Deposit date: | 2015-06-04 | | Release date: | 2015-09-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Crystal Structures of a Double-Barrelled Fluoride Ion Channel.
Nature, 525, 2015
|
|
1X78
 | | CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-244 | | Descriptor: | Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1, [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE | | Authors: | Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C. | | Deposit date: | 2004-08-13 | | Release date: | 2005-03-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
|
|
1X7B
 | | CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH ERB-041 | | Descriptor: | 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL, Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1 | | Authors: | Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C. | | Deposit date: | 2004-08-13 | | Release date: | 2005-03-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
|
|
1X7E
 | | CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA COMPLEXED WITH WAY-244 | | Descriptor: | Estrogen receptor 1 (alpha), [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE, steroid receptor coactivator-3 | | Authors: | Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C. | | Deposit date: | 2004-08-13 | | Release date: | 2005-03-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
|
|
1X76
 | | CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-697 | | Descriptor: | 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE, Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1 | | Authors: | Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C. | | Deposit date: | 2004-08-13 | | Release date: | 2005-03-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
|
|
1ZAF
 | | Crystal structure of estrogen receptor beta complexed with 3-Bromo-6-hydroxy-2-(4-hydroxy-phenyl)-inden-1-one | | Descriptor: | 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE, Estrogen receptor beta, Nuclear receptor coactivator 1 | | Authors: | McDevitt, R.E, Malamas, M.S, Manas, E.S, Unwalla, R.J, Xu, Z.B, Miller, C.P, Harris, H.A. | | Deposit date: | 2005-04-06 | | Release date: | 2006-04-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Estrogen receptor ligands: design and synthesis of new 2-arylindene-1-ones
Bioorg.Med.Chem.Lett., 15, 2005
|
|
5FBH
 | | Crystal structure of the extracellular domain of human calcium sensing receptor with bound Gd3+ | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ... | | Authors: | Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J. | | Deposit date: | 2015-12-14 | | Release date: | 2016-06-22 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
|
|
4KK8
 | |
2FED
 | | Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli | | Descriptor: | Fab fragment, heavy chain, light chain, ... | | Authors: | Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. | | Deposit date: | 2005-12-15 | | Release date: | 2006-01-03 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.317 Å) | | Cite: | Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
|
|
2FEC
 | | Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli | | Descriptor: | Fab fragment, heavy chain, light chain, ... | | Authors: | Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. | | Deposit date: | 2005-12-15 | | Release date: | 2006-01-03 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.967 Å) | | Cite: | Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
|
|
2FEE
 | | Structure of the Cl-/H+ exchanger CLC-ec1 from E.Coli in NaBr | | Descriptor: | Fab fragment, heavy chain, light chain, ... | | Authors: | Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. | | Deposit date: | 2005-12-15 | | Release date: | 2006-01-03 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
|
|
4KKL
 | | Structure of the E148A mutant of CLC-ec1 delta NC construct in 100mM fluoride | | Descriptor: | FLUORIDE ION, Fab, heavy chain, ... | | Authors: | Stockbridge, R.B, Lim, H.-H, Miller, C. | | Deposit date: | 2013-05-06 | | Release date: | 2013-08-21 | | Last modified: | 2013-12-04 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
|
|
