1ZAF
Crystal structure of estrogen receptor beta complexed with 3-Bromo-6-hydroxy-2-(4-hydroxy-phenyl)-inden-1-one
Summary for 1ZAF
Entry DOI | 10.2210/pdb1zaf/pdb |
Descriptor | Estrogen receptor beta, Nuclear receptor coactivator 1, 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE, ... (4 entities in total) |
Functional Keywords | estrogen receptor, estrogen receptor beta, er-beta, er, estrogen, nuclear receptor, transcription factor, agonist, transcription-transferase complex, transcription/transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q92731 Nucleus (By similarity): Q15788 |
Total number of polymer chains | 4 |
Total formula weight | 57221.41 |
Authors | McDevitt, R.E.,Malamas, M.S.,Manas, E.S.,Unwalla, R.J.,Xu, Z.B.,Miller, C.P.,Harris, H.A. (deposition date: 2005-04-06, release date: 2006-04-11, Last modification date: 2024-02-14) |
Primary citation | McDevitt, R.E.,Malamas, M.S.,Manas, E.S.,Unwalla, R.J.,Xu, Z.B.,Miller, C.P.,Harris, H.A. Estrogen receptor ligands: design and synthesis of new 2-arylindene-1-ones Bioorg.Med.Chem.Lett., 15:3137-3142, 2005 Cited by PubMed: 15876535DOI: 10.1016/j.bmcl.2005.04.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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