1NIH
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7PCR
| Helicobacter pylori RNase J | Descriptor: | Ribonuclease J | Authors: | Luisi, B.F, Pei, X.Y. | Deposit date: | 2021-08-03 | Release date: | 2022-05-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease. Nat Commun, 14, 2023
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1R4O
| Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | Descriptor: | 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*CP*TP*G)-3', Glucocorticoid receptor, ZINC ION | Authors: | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | Deposit date: | 2003-10-07 | Release date: | 2003-10-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystallographic Analysis of the Interaction of The Glucocorticoid Receptor with DNA Nature, 352, 1991
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1R4R
| Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | Descriptor: | 5'-D(*CP*TP*GP*AP*GP*AP*AP*CP*AP*TP*CP*AP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*TP*GP*AP*TP*GP*TP*TP*CP*TP*CP*A)-3', Glucocorticoid receptor, ... | Authors: | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | Deposit date: | 2003-10-07 | Release date: | 2003-10-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystallographic Analysis of the Interaction of the Glucocorticoid Receptor with DNA Nature, 352, 1991
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1COH
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1GLU
| CRYSTALLOGRAPHIC ANALYSIS OF THE INTERACTION OF THE GLUCOCORTICOID RECEPTOR WITH DNA | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*C P*TP*G)-3'), PROTEIN (GLUCOCORTICOID RECEPTOR), ZINC ION | Authors: | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | Deposit date: | 1992-08-30 | Release date: | 1994-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA. Nature, 352, 1991
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5NQB
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5NQQ
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2FIC
| The crystal structure of the BAR domain from human Bin1/Amphiphysin II and its implications for molecular recognition | Descriptor: | Myc box-dependent-interacting protein 1, XENON | Authors: | Casal, E, Federici, L, Zhang, W, Fernandez-Recio, J, Priego, E.M, Miguel, R.N, Duhadaway, J.B, Prendergast, G.C, Luisi, B.F, Laue, E.D. | Deposit date: | 2005-12-29 | Release date: | 2006-11-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The Crystal Structure of the BAR Domain from Human Bin1/Amphiphysin II and Its Implications for Molecular Recognition Biochemistry, 45, 2006
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1LR0
| Pseudomonas aeruginosa TolA Domain III, Seleno-methionine Derivative | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, TolA protein, ZINC ION | Authors: | Witty, M, Sanz, C, Shah, A, Grossman, J.G, Mizuguchi, K, Perham, R.N, Luisi, B. | Deposit date: | 2002-05-14 | Release date: | 2002-05-29 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (1.914 Å) | Cite: | Structure of the periplasmic domain of Pseudomonas aeruginosa TolA: evidence for an evolutionary relationship with the TonB transporter protein. EMBO J., 21, 2002
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4UOT
| Thermodynamic hyperstability in parametrically designed helical bundles | Descriptor: | DESIGNED HELICAL BUNDLE 5H2L | Authors: | Oberdorfer, G, Huang, P, Pei, X.Y, Xu, C, Gonen, T, Nannenga, B, DiMaio, D, Rogers, J, Luisi, B.F, Baker, D. | Deposit date: | 2014-06-09 | Release date: | 2014-11-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | High Thermodynamic Stability of Parametrically Designed Helical Bundles Science, 346, 2014
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4UOS
| Thermodynamic hyperstability in parametrically designed helical bundles | Descriptor: | DESIGNED HELICAL BUNDLE | Authors: | Oberdorfer, G, Huang, P, Pei, X.Y, Xu, C, Gonen, T, Nannenga, B, DiMaio, D, Rogers, J, Luisi, B.F, Baker, D. | Deposit date: | 2014-06-09 | Release date: | 2014-11-05 | Last modified: | 2016-12-14 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | High Thermodynamic Stability of Parametrically Designed Helical Bundles Science, 346, 2014
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4V2S
| Crystal structure of Hfq in complex with the sRNA RydC | Descriptor: | RNA-BINDING PROTEIN HFQ, RYDC | Authors: | Dimastrogiovanni, D, Frohlich, K.S, Bruce, H.A, Bandyra, K.J, Hohensee, S, Vogel, J, Luisi, B.F. | Deposit date: | 2014-10-14 | Release date: | 2015-01-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | Recognition of the small regulatory RNA RydC by the bacterial Hfq protein. Elife, 3, 2014
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6G63
| RNase E in complex with sRNA RrpA | Descriptor: | RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), Ribonuclease E, URIDINE-5'-MONOPHOSPHATE, ... | Authors: | Bandyra, K.B, Luisi, B.F. | Deposit date: | 2018-03-31 | Release date: | 2018-10-03 | Last modified: | 2018-10-31 | Method: | X-RAY DIFFRACTION (3.95 Å) | Cite: | Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E. Mol. Cell, 72, 2018
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8B0I
| CryoEM structure of bacterial RapZ.GlmZ complex central to the control of cell envelope biogenesis | Descriptor: | GlmZ small regulatory RNA, RNase adapter protein RapZ | Authors: | Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F. | Deposit date: | 2022-09-07 | Release date: | 2022-10-05 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (4.28 Å) | Cite: | Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis. Embo J., 42, 2023
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8B0J
| CryoEM structure of bacterial RNaseE.RapZ.GlmZ complex central to the control of cell envelope biogenesis | Descriptor: | GlmZ small RNA, RNase adapter protein RapZ, Ribonuclease E | Authors: | Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F. | Deposit date: | 2022-09-07 | Release date: | 2022-10-05 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis. Embo J., 42, 2023
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5NIK
| Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump | Descriptor: | Macrolide export ATP-binding/permease protein MacB, Macrolide export protein MacA, Outer membrane protein TolC | Authors: | Fitzpatrick, A.W.P, Llabres, S, Neuberger, A, Blaza, J.N, Bai, X.-C, Okada, U, Murakami, S, van Veen, H.W, Zachariae, U, Scheres, S.H.W, Luisi, B.F, Du, D. | Deposit date: | 2017-03-24 | Release date: | 2017-05-24 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump. Nat Microbiol, 2, 2017
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7AU2
| Cryo-EM structure of human exostosin-like 3 (EXTL3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-like 3, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Wilson, L.F.L, Dendooven, T, Hardwick, S.W, Chirgadze, D.Y, Luisi, B.F, Logan, D.T, Mani, K, Dupree, P. | Deposit date: | 2020-11-02 | Release date: | 2022-05-18 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis. Nat Commun, 13, 2022
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7AUA
| Cryo-EM structure of human exostosin-like 3 (EXTL3) in complex with UDP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-like 3, MANGANESE (II) ION, ... | Authors: | Wilson, L.F.L, Dendooven, T, Hardwick, S.W, Chirgadze, D.Y, Luisi, B.F, Logan, D.T, Mani, K, Dupree, P. | Deposit date: | 2020-11-02 | Release date: | 2022-05-18 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis. Nat Commun, 13, 2022
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5V5S
| multi-drug efflux; membrane transport; RND superfamily; Drug resistance | Descriptor: | Multidrug efflux pump subunit AcrA, Multidrug efflux pump subunit AcrB, Outer membrane protein TolC | Authors: | wang, Z, fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D. | Deposit date: | 2017-03-15 | Release date: | 2017-04-19 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump. Elife, 6, 2017
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1IBE
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6HCK
| The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with dipeptide Leu-Leu | Descriptor: | LEUCINE, Listeriolysin regulatory protein, SODIUM ION | Authors: | Grundstrom, C, Oelker, M, Krypotou, E, Scortti, M, Luisi, B.F, Vazquez-Boland, J, Sauer-Eriksson, A.E. | Deposit date: | 2018-08-15 | Release date: | 2019-02-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Control of Bacterial Virulence through the Peptide Signature of the Habitat. Cell Rep, 26, 2019
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6GWK
| The crystal structure of Hfq from Caulobacter crescentus | Descriptor: | RNA-binding protein Hfq | Authors: | Santiago-Frangos, A, Frohlich, K.S, Jeliazkov, J.R, Gray, J.R, Luisi, B.F, Woodson, S.A, Hardwick, S.W. | Deposit date: | 2018-06-25 | Release date: | 2019-05-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Caulobacter crescentusHfq structure reveals a conserved mechanism of RNA annealing regulation. Proc.Natl.Acad.Sci.USA, 116, 2019
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7OGL
| A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation. apo-PNPase | Descriptor: | Polyribonucleotide nucleotidyltransferase | Authors: | Dendooven, T, Sinha, D, Roesoleva, A, Cameron, T.A, De Lay, N, Luisi, B.F, Bandyra, K. | Deposit date: | 2021-05-06 | Release date: | 2021-07-07 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation. Mol.Cell, 81, 2021
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7OGK
| A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation. PNPase-3'ETS(leuZ) | Descriptor: | 3'ETS(LeuZ), Polyribonucleotide nucleotidyltransferase | Authors: | Dendooven, T, Sinha, D, Roesoleva, A, Cameron, T.A, De Lay, N, Luisi, B.F, Bandyra, K. | Deposit date: | 2021-05-06 | Release date: | 2021-07-07 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation. Mol.Cell, 81, 2021
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