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PDB: 39 results

3VP6
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Structural characterization of Glutamic Acid Decarboxylase; insights into the mechanism of autoinactivation
Descriptor: 4-oxo-4H-pyran-2,6-dicarboxylic acid, GLYCEROL, Glutamate decarboxylase 1
Authors:Langendorf, C.G, Tuck, K.L, Key, T.L.G, Rosado, C.J, Wong, A.S.M, Fenalti, G, Buckle, A.M, Law, R.H.P, Whisstock, J.C.
Deposit date:2012-02-27
Release date:2013-01-16
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates
Biosci.Rep., 33, 2013
3ZLH
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Structure of group A Streptococcal enolase
Descriptor: ENOLASE
Authors:Cork, A.J, Ericsson, D.J, Law, R.H.P, Casey, L.W, Valkov, E, Bertozzi, C, Stamp, A, Aquilina, J.A, Whisstock, J.C, Walker, M.J, Kobe, B.
Deposit date:2013-01-31
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Stability of the Octameric Structure Affects Plasminogen-Binding Capacity of Streptococcal Enolase.
Plos One, 10, 2015
3ZLF
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Structure of group A Streptococcal enolase K312A mutant
Descriptor: ENOLASE, PHOSPHATE ION
Authors:Cork, A.J, Ericsson, D.J, Law, R.H.P, Casey, L.W, Valkov, E, Bertozzi, C, Stamp, A, Aquilina, J.A, Whisstock, J.C, Walker, M.J, Kobe, B.
Deposit date:2013-01-31
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Stability of the Octameric Structure Affects Plasminogen-Binding Capacity of Streptococcal Enolase.
Plos One, 10, 2015
3ZLG
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Structure of group A Streptococcal enolase K362A mutant
Descriptor: ENOLASE, PHOSPHATE ION
Authors:Cork, A.J, Ericsson, D.J, Law, R.H.P, Casey, L.W, Valkov, E, Bertozzi, C, Stamp, A, Aquilina, J.A, Whisstock, J.C, Walker, M.J, Kobe, B.
Deposit date:2013-01-31
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Stability of the Octameric Structure Affects Plasminogen-Binding Capacity of Streptococcal Enolase.
Plos One, 10, 2015
2OKK
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BU of 2okk by Molmil
The X-ray crystal structure of the 65kDa isoform of Glutamic Acid Decarboxylase (GAD65)
Descriptor: GAMMA-AMINO-BUTANOIC ACID, GLYCEROL, Glutamate decarboxylase 2
Authors:Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C.
Deposit date:2007-01-17
Release date:2007-03-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
4OV8
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BU of 4ov8 by Molmil
Crystal Structure of the TMH1-lock mutant of the mature form of pleurotolysin B
Descriptor: CHLORIDE ION, GLYCEROL, Pleurotolysin B, ...
Authors:Kondos, S.C, Law, R.H.P, Whisstock, J.C, Dunstone, M.A.
Deposit date:2014-02-20
Release date:2015-02-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin
Plos Biol., 13, 2015
6DLW
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BU of 6dlw by Molmil
Complement component polyC9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement component C9, beta-D-mannopyranose
Authors:Dunstone, M.A, Spicer, B.A, Law, R.H.P.
Deposit date:2018-06-03
Release date:2018-09-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
4OEJ
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Structure of membrane binding protein pleurotolysin B from Pleurotus ostreatus
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Dunstone, M.A, Caradoc-Davies, T.T, Whisstock, J.C, Law, R.H.P.
Deposit date:2014-01-13
Release date:2015-02-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
4OEB
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BU of 4oeb by Molmil
Structure of membrane binding protein pleurotolysin A from Pleurotus ostreatus
Descriptor: Pleurotolysin A, SULFATE ION
Authors:Dunstone, M.A, Caradoc-Davies, T.T, Whisstock, J.C, Law, R.H.P.
Deposit date:2014-01-12
Release date:2015-02-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
4P48
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BU of 4p48 by Molmil
The structure of a chicken anti-cardiac Troponin I scFv
Descriptor: Antibody scFv 180
Authors:Conroy, P.J, Law, R.H.P, Gillgunn, S, Hearty, S, Caradoc-Davies, T.T, Llyod, G, O'Kennedy, R.J, Whisstock, J.C.
Deposit date:2014-03-12
Release date:2014-04-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Reconciling the structural attributes of avian antibodies.
J.Biol.Chem., 289, 2014
4P49
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BU of 4p49 by Molmil
The structure of a chicken anti-prostate specific antigen scFv
Descriptor: ACETATE ION, Antibody scFv B8, SULFATE ION
Authors:Conroy, P.J, Law, R.H.P, Gilgunn, S, Hearty, S, Llyod, G, Caradoc-Davies, T.T, O'Kennedy, R.J, Whisstock, J.C.
Deposit date:2014-03-12
Release date:2014-04-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Reconciling the structural attributes of avian antibodies.
J.Biol.Chem., 289, 2014
3JZ4
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Crystal structure of E. coli NADP dependent enzyme
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Succinate-semialdehyde dehydrogenase [NADP+]
Authors:Langendorf, C.G, Key, T.L.G, Fenalti, G, Kan, W.T, Buckle, A.M, Caradoc-Davies, T, Tuck, K.L, Law, R.H.P, Whisstock, J.C.
Deposit date:2009-09-22
Release date:2010-03-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions.
Plos One, 5, 2010
2QP2
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BU of 2qp2 by Molmil
Structure of a MACPF/perforin-like protein
Descriptor: CALCIUM ION, Unknown protein
Authors:Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C.
Deposit date:2007-07-22
Release date:2007-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A common fold mediates vertebrate defense and bacterial attack
Science, 317, 2007
2VH4
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Structure of a loop C-sheet serpin polymer
Descriptor: TENGPIN
Authors:Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M.
Deposit date:2007-11-19
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A Structural Basis for Loop C-Sheet Polymerization in Serpins.
J.Mol.Biol., 376, 2008
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