3VP6

Structural characterization of Glutamic Acid Decarboxylase; insights into the mechanism of autoinactivation

Summary for 3VP6

Entry DOI	10.2210/pdb3vp6/pdb
Descriptor	Glutamate decarboxylase 1, 4-oxo-4H-pyran-2,6-dicarboxylic acid, GLYCEROL, ... (4 entities in total)
Functional Keywords	catalytic loop swap, lyase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	117411.82
Authors	Langendorf, C.G.,Tuck, K.L.,Key, T.L.G.,Rosado, C.J.,Wong, A.S.M.,Fenalti, G.,Buckle, A.M.,Law, R.H.P.,Whisstock, J.C. (deposition date: 2012-02-27, release date: 2013-01-16, Last modification date: 2013-08-14)
Primary citation	Langendorf, C.G.,Tuck, K.L.,Key, T.L.G.,Fenalti, G.,Pike, R.N.,Rosado, C.J.,Wong, A.S.M.,Buckle, A.M.,Law, R.H.P.,Whisstock, J.C. Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates Biosci.Rep., 33:137-144, 2013 Cited by PubMed: 23126365 DOI: 10.1042/BSR20120111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation