7OPQ
 
 | | Rab27a fusion with Slp2a-RBDa1 effector covalent adduct with CA1 in C188 | | Descriptor: | 1-[(2~{S})-2-(4-methoxyphenyl)pyrrolidin-1-yl]propan-1-one, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | | Deposit date: | 2021-06-01 | | Release date: | 2022-04-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.
Rsc Med Chem, 13, 2022
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7OPR
 | | Rab27a fusion with Slp2a-RBDa1 effector covalent adduct with CB1 in C123 | | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | | Deposit date: | 2021-06-01 | | Release date: | 2022-04-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.
Rsc Med Chem, 13, 2022
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7OPP
 | | Crystal structure of the Rab27a fusion with Slp2a-RBDa1 effector for SF4 pocket drug targeting | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Synaptotagmin-like protein 2,Ras-related protein Rab-27A | | Authors: | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | | Deposit date: | 2021-06-01 | | Release date: | 2022-04-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.
Rsc Med Chem, 13, 2022
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6FCO
 | | Structural and functional characterisation of Frataxin (FXN) like protein from Chaetomium thermophilum | | Descriptor: | MALONIC ACID, Mitochondrial frataxin-like protein | | Authors: | Jamshidiha, M, Rasheed, M, Pastore, A, Cota, E. | | Deposit date: | 2017-12-20 | | Release date: | 2019-01-23 | | Last modified: | 2019-02-13 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structural and functional characterization of a frataxin from a thermophilic organism.
FEBS J., 286, 2019
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6HUF
 | | Coping with strong translational non-crystallographic symmetry and extreme anisotropy in molecular replacement with Phaser: human Rab27a | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-27A | | Authors: | Jamshidiha, M, Perez-Dorado, I, Murray, J.W, Tate, E.W, Cota, E, Read, R.J. | | Deposit date: | 2018-10-08 | | Release date: | 2019-03-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.82 Å) | | Cite: | Coping with strong translational noncrystallographic symmetry and extreme anisotropy in molecular replacement with Phaser: human Rab27a.
Acta Crystallogr D Struct Biol, 75, 2019
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2M7E
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2M73
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4SGB
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5FUI
 | | Crystal structure of the C-terminal CBM6 of LamC a marine laminarianse from Zobellia galactanivorans | | Descriptor: | 2-AMINOMETHYL-PYRIDINE, ENDO-1,3-BETA-GLUCANASE, FAMILY GH16, ... | | Authors: | Labourel, A, Jam, M, Legentil, L, Sylla, B, Hehemann, J.H, Ficko-Blean, E, Ferrieres, V, Czjzek, M, Michel, G. | | Deposit date: | 2016-01-27 | | Release date: | 2016-03-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Unraveling the Multivalent Binding of a Marine Family 6 Carbohydrate-Binding Module with its Native Laminarin Ligand.
FEBS J., 283, 2016
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1O4Z
 | | THE THREE-DIMENSIONAL STRUCTURE OF BETA-AGARASE B FROM ZOBELLIA GALACTANIVORANS | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, SODIUM ION, ... | | Authors: | Allouch, J, Jam, M, Helbert, W, Barbeyron, T, Kloareg, B, Henrissat, B, Czjzek, M. | | Deposit date: | 2003-07-29 | | Release date: | 2003-12-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The Three-dimensional Structures of Two {beta}-Agarases.
J.Biol.Chem., 278, 2003
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1O4Y
 | | THE THREE-DIMENSIONAL STRUCTURE OF BETA-AGARASE A FROM ZOBELLIA GALACTANIVORANS | | Descriptor: | CALCIUM ION, SODIUM ION, SULFATE ION, ... | | Authors: | Allouch, J, Jam, M, Helbert, W, Barbeyron, T, Kloareg, B, Henrissat, B, Czjzek, M. | | Deposit date: | 2003-07-29 | | Release date: | 2003-12-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | The Three-dimensional Structures of Two {beta}-Agarases.
J.Biol.Chem., 278, 2003
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5OLC
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4ATE
 | | High resolution crystal structure of beta-porphyranase A from Zobellia galactanivorans | | Descriptor: | BETA-PORPHYRANASE A, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Hehemann, J.H, Correc, G, Jam, M, Michel, G, Czjzek, M. | | Deposit date: | 2012-05-06 | | Release date: | 2012-07-25 | | Last modified: | 2019-05-08 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Biochemical and Structural Characterization of the Complex Agarolytic Enzyme System from the Marine Bacterium Zobellia Galactanivorans.
J.Biol.Chem., 287, 2012
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4ATF
 | | Crystal structure of inactivated mutant beta-agarase B in complex with agaro-octaose | | Descriptor: | 3,6-anhydro-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-3,6-anhydro-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-3,6-anhydro-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-3,6-anhydro-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose, BETA-AGARASE B, SODIUM ION | | Authors: | Bernard, T, Hehemann, J.H, Correc, G, Jam, M, Michel, G, Czjzek, M. | | Deposit date: | 2012-05-06 | | Release date: | 2012-07-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Biochemical and Structural Characterization of the Complex Agarolytic Enzyme System from the Marine Bacterium Zobellia Galactanivorans.
J.Biol.Chem., 287, 2012
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4CRQ
 | | Crystal structure of the catalytic domain of the modular laminarinase ZgLamC mutant E142S | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | Authors: | Labourel, A, Jam, M, Legentil, L, Sylla, B, Ficko-Blean, E, Hehemann, J.H, Ferrieres, V, Czjzek, M, Michel, G. | | Deposit date: | 2014-02-28 | | Release date: | 2015-01-14 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural and Biochemical Characterization of the Laminarina Zglamc[Gh16] from Zobellia Galactanivorans Suggests Preferred Recognition of Branched Laminarin
Acta Crystallogr.,Sect.D, 71, 2015
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4BPZ
 | | Crystal structure of lamA_E269S from Zobellia galactanivorans in complex with a trisaccharide of 1,3-1,4-beta-D-glucan. | | Descriptor: | CALCIUM ION, ENDO-1,3-BETA-GLUCANASE, FAMILY GH16, ... | | Authors: | Labourel, A, Jam, M, Jeudy, A, Czjzek, M, Michel, G. | | Deposit date: | 2013-05-29 | | Release date: | 2013-12-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.13 Å) | | Cite: | The Beta-Glucanase Zglama from Zobellia Galactanivorans Evolved a Bent Active Site Adapted for Efficient Degradation of Algal Laminarin.
J.Biol.Chem., 289, 2014
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4CTE
 | | Crystal structure of the catalytic domain of the modular laminarinase ZgLamC mutant E142S in complex with a thio-oligosaccharide | | Descriptor: | 1,2-ETHANEDIOL, 1-thio-beta-D-glucopyranose-(1-3)-1-thio-beta-D-glucopyranose, ACETATE ION, ... | | Authors: | Labourel, A, Jam, M, Legentil, L, Sylla, B, Ficko-Blean, E, Hehemann, J.H, Ferrieres, V, Czjzek, M, Michel, G. | | Deposit date: | 2014-03-13 | | Release date: | 2015-01-14 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and Biochemical Characterization of the Laminarina Zglamc[Gh16] from Zobellia Galactanivorans Suggests Preferred Recognition of Branched Laminarin
Acta Crystallogr.,Sect.D, 71, 2015
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4BQ1
 | | Crystal structure of of LamAcat from Zobellia galactanivorans | | Descriptor: | CALCIUM ION, ENDO-1,3-BETA-GLUCANASE, FAMILY GH16, ... | | Authors: | Labourel, A, Jam, M, Jeudy, A, Michel, G, Czjzek, M. | | Deposit date: | 2013-05-29 | | Release date: | 2013-12-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The Beta Glucanase Zglama from Zobellia Galactanivorans Evolved a Bent Active Site Adapted for Efficient Degradation of Algal Laminarin
J.Biol.Chem., 289, 2014
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3L32
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8B8V
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7PON
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7PNO
 | | C terminal domain of Nipah Virus Phosphoprotein fused to the Ntail alpha more of the Nucleoprotein. | | Descriptor: | Phosphoprotein, alpha MoRE of Nipah virus Nucleoprotein tail | | Authors: | Bourhis, J.M, Yabukaski, F, Tarbouriech, N, Jamin, M. | | Deposit date: | 2021-09-07 | | Release date: | 2022-04-20 | | Last modified: | 2022-04-27 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Structural Dynamics of the C-terminal X Domain of Nipah and Hendra Viruses Controls the Attachment to the C-terminal Tail of the Nucleocapsid Protein.
J.Mol.Biol., 434, 2022
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4TYH
 | | Ternary complex of P38 and MK2 with a P38 inhibitor | | Descriptor: | MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14, N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide | | Authors: | Cumming, J.G, Debreczeni, J.E, Edfeldt, F, Evertsson, F, Harrison, M, Holdgate, G, James, M, Lamont, S, Oldham, K, Sullivan, J.E, Wells, S. | | Deposit date: | 2014-07-08 | | Release date: | 2015-07-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Discovery of substrate selective, ATP-competitive P38 alpha MAP kinase inhibitors
To Be Published
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5MDI
 | | Crystal structure of TDP-43 N-terminal domain at 2.1 A resolution | | Descriptor: | ACETATE ION, TAR DNA-binding protein 43 | | Authors: | Afroz, T, Hock, E.-M, Ernst, P, Foglieni, C, Jambeau, M, Gilhespy, L, Laferriere, F, Maniecka, Z, Plueckthun, A, Mittl, P, Paganetti, P, Allain, F.H.T, Polymenidou, M. | | Deposit date: | 2016-11-11 | | Release date: | 2017-07-05 | | Last modified: | 2017-07-12 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation.
Nat Commun, 8, 2017
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8BJW
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