Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 321 results
7Z43
DownloadVisualize
BU of 7z43 by Molmil
Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 1B and 2B
Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Cusack, S, Drncova, P.
Deposit date:2022-03-03
Release date:2022-05-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.123 Å)
Cite:Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
7Z42
DownloadVisualize
BU of 7z42 by Molmil
Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 2B
Descriptor: DNA-directed RNA polymerase II subunit RPB1, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Cusack, S, Drncova, P.
Deposit date:2022-03-03
Release date:2022-05-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.418 Å)
Cite:Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
7Z4O
DownloadVisualize
BU of 7z4o by Molmil
Influenza A/H7N9 polymerase core dimer with Pol II pSer5 CTD peptide mimic bound in site 2A
Descriptor: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Cusack, S, Pflug, A.
Deposit date:2022-03-04
Release date:2022-05-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.412 Å)
Cite:Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
7ALP
DownloadVisualize
BU of 7alp by Molmil
Severe fever with thrombocytopenia syndrome virus (Phenuiviridae) L protein
Descriptor: MAGNESIUM ION, Replicase
Authors:Cusack, S, Rosenthal, M.
Deposit date:2020-10-07
Release date:2021-04-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Errors in the deposited SFTSV L protein structure.
Nat Microbiol, 6, 2021
5JBJ
DownloadVisualize
BU of 5jbj by Molmil
Crystal structure of chicken LGP2 with 5'p 12-mer dsRNA at 3.6 A resolution
Descriptor: LGP2, RNA (5'-R(P*GP*GP*UP*AP*GP*CP*GP*CP*UP*AP*CP*C)-3'), ZINC ION
Authors:Cusack, S, Uchikawa, E, Lethier, M.
Deposit date:2016-04-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JC3
DownloadVisualize
BU of 5jc3 by Molmil
Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.6 A resolution (monoclinic form, twinned).
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-14
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JCF
DownloadVisualize
BU of 5jcf by Molmil
Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.6 A resolution (orthorhombic form).
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-15
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JC7
DownloadVisualize
BU of 5jc7 by Molmil
Crystal structure of chicken MDA5 with 5'p 24-mer dsRNA and ADP-Mg2+ at 2.75 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-14
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JAJ
DownloadVisualize
BU of 5jaj by Molmil
Structure of chicken LGP2 witha 5'p 10-mer dsRNA and ADP-AlF4-Mg.
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, LGP2, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-12
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JB2
DownloadVisualize
BU of 5jb2 by Molmil
Crystal structure of chicken LGP2 with 5'ppp 10-mer dsRNA and ADP-AlF4-Mg2+ at 2.2 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, LGP2, MAGNESIUM ION, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
4WSB
DownloadVisualize
BU of 4wsb by Molmil
Bat Influenza A polymerase with bound vRNA promoter
Descriptor: Influenza A polymerase vRNA promoter 3' end, Influenza A polymerase vRNA promoter 5' end, PHOSPHATE ION, ...
Authors:Cusack, S, Pflug, A, Guilligay, D, Reich, S.
Deposit date:2014-10-26
Release date:2014-11-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516, 2014
1SET
DownloadVisualize
BU of 1set by Molmil
CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, SERYL-tRNA SYNTHETASE
Authors:Cusack, S, Belrhali, H.
Deposit date:1994-02-21
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate.
Science, 263, 1994
7QTL
DownloadVisualize
BU of 7qtl by Molmil
Influenza A/H7N9 polymerase elongation complex
Descriptor: 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-01-14
Release date:2022-12-28
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
1SES
DownloadVisualize
BU of 1ses by Molmil
CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE
Descriptor: ADENOSINE MONOPHOSPHATE, SERYL-HYDROXAMATE-ADENOSINE MONOPHOSPHATE, SERYL-tRNA SYNTHETASE
Authors:Cusack, S, Belrhali, H.
Deposit date:1994-02-21
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate.
Science, 263, 1994
1OBH
DownloadVisualize
BU of 1obh by Molmil
LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A PRE-TRANSFER EDITING SUBSTRATE ANALOGUE IN BOTH SYNTHETIC ACTIVE SITE AND EDITING SITE
Descriptor: LEUCYL-TRNA SYNTHETASE, MERCURY (II) ION, NORVALINE, ...
Authors:Cusack, S, Yaremchuk, A, Tukalo, M.
Deposit date:2003-01-31
Release date:2003-05-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase
Mol.Cell, 11, 2003
7R0E
DownloadVisualize
BU of 7r0e by Molmil
Early transcription elongation state of influenza A/H7N9 polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the +1 position
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-02-01
Release date:2022-12-28
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
7R1F
DownloadVisualize
BU of 7r1f by Molmil
Early transcription elongation state of influenza B polymerase backtracked due to double incoproation of nucleotide analogue T1106
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-02-02
Release date:2022-12-28
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
1OBC
DownloadVisualize
BU of 1obc by Molmil
LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A POST-TRANSFER EDITING SUBSTRATE ANALOGUE
Descriptor: 2'-AMINO-2'-DEOXYADENOSINE, LEUCINE, LEUCYL-TRNA SYNTHETASE, ...
Authors:Cusack, S, Yaremchuk, A, Tukalo, M.
Deposit date:2003-01-30
Release date:2003-05-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase
Mol.Cell, 11, 2003
6Z6B
DownloadVisualize
BU of 6z6b by Molmil
Structure of full-length La Crosse virus L protein (polymerase)
Descriptor: RNA (5'-R(*GP*CP*UP*AP*CP*UP*AP*A)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*GP*UP*GP*C)-3'), RNA (5'-R(P*UP*UP*AP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), ...
Authors:Cusack, S, Gerlach, P, Reguera, J.
Deposit date:2020-05-28
Release date:2020-07-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.961 Å)
Cite:Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
7ZPM
DownloadVisualize
BU of 7zpm by Molmil
Influenza A/H7N9 polymerase apo-protein dimer complex
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit
Authors:Cusack, S, Kouba, T.
Deposit date:2022-04-27
Release date:2022-12-28
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
7ZPL
DownloadVisualize
BU of 7zpl by Molmil
Symmetric dimer of influenza A/H7N9 polymerase bound to 5' vRNA hook
Descriptor: 5' vRNA, MAGNESIUM ION, Polymerase acidic protein, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-04-27
Release date:2022-12-28
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BDR
DownloadVisualize
BU of 8bdr by Molmil
Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the U +1 position
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-10-19
Release date:2022-12-28
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BE0
DownloadVisualize
BU of 8be0 by Molmil
Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the C +1 position
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-10-20
Release date:2022-12-28
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BEK
DownloadVisualize
BU of 8bek by Molmil
Early transcription elongation state of influenza A/H7N9 backtracked polymerase with singly incoporated T1106 at the U +1 position
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-10-21
Release date:2022-12-28
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BF5
DownloadVisualize
BU of 8bf5 by Molmil
Early transcription elongation state of influenza A/H7N9 polymerase stalled with incoming GTP analogue
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-10-24
Release date:2022-12-28
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023

221051

PDB entries from 2024-06-12

PDB statisticsPDBj update infoContact PDBjnumon