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PDB: 280 results

1I3Q
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RNA POLYMERASE II CRYSTAL FORM I AT 3.1 A RESOLUTION
Descriptor: DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ...
Authors:Cramer, P, Bushnell, D.A, Kornberg, R.D.
Deposit date:2001-02-15
Release date:2001-04-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
Science, 292, 2001
1I50
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RNA POLYMERASE II CRYSTAL FORM II AT 2.8 A RESOLUTION
Descriptor: DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ...
Authors:Cramer, P, Bushnell, D.A, Kornberg, R.D.
Deposit date:2001-02-23
Release date:2001-04-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
Science, 292, 2001
1A3Q
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HUMAN NF-KAPPA-B P52 BOUND TO DNA
Descriptor: DNA (5'-D(*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*CP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B P52)
Authors:Cramer, P, Larson, C.J, Verdine, G.L, Muller, C.W.
Deposit date:1998-01-23
Release date:1998-06-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution.
EMBO J., 16, 1997
1BRI
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BARNASE MUTANT WITH ILE 76 REPLACED BY ALA
Descriptor: BARNASE
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1BRK
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BARNASE MUTANT WITH ILE 96 REPLACED BY ALA
Descriptor: BARNASE, ZINC ION
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1Y1W
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BU of 1y1w by Molmil
Complete RNA Polymerase II elongation complex
Descriptor: 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*AP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ...
Authors:Cramer, P, Kettenberger, H, Armache, K.-J.
Deposit date:2004-11-19
Release date:2005-01-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (4 Å)
Cite:Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
Mol.Cell, 16, 2004
1BRJ
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BU of 1brj by Molmil
BARNASE MUTANT WITH ILE 88 REPLACED BY ALA
Descriptor: BARNASE, ZINC ION
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1BRH
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BARNASE MUTANT WITH LEU 14 REPLACED BY ALA
Descriptor: BARNASE, ZINC ION
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1Y1Y
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BU of 1y1y by Molmil
RNA Polymerase II-TFIIS-DNA/RNA complex
Descriptor: 5'-D(P*TP*AP*CP*GP*CP*CP*T)-3', 5'-R(P*AP*GP*GP*C)-3', DNA-directed RNA polymerase II 13.6 kDa polypeptide, ...
Authors:Cramer, P, Kettenberger, H, Armache, K.-J.
Deposit date:2004-11-19
Release date:2004-12-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.
Mol.Cell, 16, 2004
1BVO
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BU of 1bvo by Molmil
DORSAL HOMOLOGUE GAMBIF1 BOUND TO DNA
Descriptor: DNA DUPLEX, TRANSCRIPTION FACTOR GAMBIF1
Authors:Cramer, P, Varrot, A, Barillas-Mury, C, Kafatos, F.C, Mueller, C.W.
Deposit date:1998-09-16
Release date:1999-07-12
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the specificity domain of the Dorsal homologue Gambif1 bound to DNA.
Structure Fold.Des., 7, 1999
4A93
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BU of 4a93 by Molmil
RNA Polymerase II elongation complex containing a CPD Lesion
Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ...
Authors:Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M.
Deposit date:2011-11-23
Release date:2012-03-21
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
Mol.Cell, 46, 2012
3C0T
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BU of 3c0t by Molmil
Structure of the Schizosaccharomyces pombe Mediator subcomplex Med8C/18
Descriptor: Mediator of RNA polymerase II transcription subunit 18, Mediator of RNA polymerase II transcription subunit 8
Authors:Lariviere, L, Seizl, M, van Wageningen, S, Roether, S, van de Pasch, L, Feldmann, H, Straesser, K, Hahn, S, Holstege, C.P, Cramer, P.
Deposit date:2008-01-21
Release date:2008-04-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-system correlation identifies a gene regulatory Mediator submodule
Genes Dev., 22, 2008
4V1O
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BU of 4v1o by Molmil
Architecture of the RNA polymerase II-Mediator core transcription initiation complex
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P.
Deposit date:2014-09-29
Release date:2015-02-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
4V1N
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BU of 4v1n by Molmil
Architecture of the RNA polymerase II-Mediator core transcription initiation complex
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P.
Deposit date:2014-09-29
Release date:2015-02-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
4V1M
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BU of 4v1m by Molmil
Architecture of the RNA polymerase II-Mediator core transcription initiation complex
Descriptor: 5'-D(*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-D(*CP*CP*AP*GP*GP*AP)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP*TP*TP*CP *CP*BRUP*GP*GP*TP*C)-3', ...
Authors:Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P.
Deposit date:2014-09-29
Release date:2015-02-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
6ERQ
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BU of 6erq by Molmil
Structure of the human mitochondrial transcription initiation complex at the HSP promoter
Descriptor: DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ...
Authors:Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P.
Deposit date:2017-10-18
Release date:2017-11-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
6ERO
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BU of 6ero by Molmil
Structure of human TFB2M
Descriptor: CHLORIDE ION, Dimethyladenosine transferase 2, mitochondrial,Dimethyladenosine transferase 2, ...
Authors:Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P.
Deposit date:2017-10-18
Release date:2017-11-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
6I84
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BU of 6i84 by Molmil
Structure of transcribing RNA polymerase II-nucleosome complex
Descriptor: DNA (158-MER), DNA (170-MER), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Farnung, L, Vos, S.M, Cramer, P.
Deposit date:2018-11-19
Release date:2019-01-02
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure of transcribing RNA polymerase II-nucleosome complex.
Nat Commun, 9, 2018
9GD1
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BU of 9gd1 by Molmil
Structure of Chd1 bound to a hexasome-nucleosome complex with a dyad-to-dyad distance of 103 bp.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ...
Authors:Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L.
Deposit date:2024-08-04
Release date:2024-09-18
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Mol.Cell, 84, 2024
9GD2
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BU of 9gd2 by Molmil
Structure of Chd1 bound to a dinucleosome with a dyad-to-dyad distance of 103 bp.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ...
Authors:Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L.
Deposit date:2024-08-04
Release date:2024-09-18
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Mol.Cell, 84, 2024
9GD0
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BU of 9gd0 by Molmil
Structure of a hexasome-nucleosome complex with a dyad-to-dyad distance of 103 bp.
Descriptor: DNA (250-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L.
Deposit date:2024-08-04
Release date:2024-09-18
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Mol.Cell, 84, 2024
4YM7
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BU of 4ym7 by Molmil
RNA polymerase I structure with an alternative dimer hinge
Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
Authors:Kostrewa, D, Kuhn, C.-D, Engel, C, Cramer, P.
Deposit date:2015-03-06
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:An alternative RNA polymerase I structure reveals a dimer hinge.
Acta Crystallogr.,Sect.D, 71, 2015
9GD3
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Structure of a mononucleosome bound by one copy of Chd1 with the DBD on the exit-side DNA.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ...
Authors:Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L.
Deposit date:2024-08-04
Release date:2024-09-18
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Mol.Cell, 84, 2024
5OT2
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BU of 5ot2 by Molmil
RNA polymerase II elongation complex in the presence of 3d-Napht-A
Descriptor: 2-ethyl-7-methoxy-naphthalene, DNA non-template strand, DNA template strand, ...
Authors:Malvezzi, S, Farnung, L, Aloisi, C, Angelov, T, Cramer, P, Sturla, S.J.
Deposit date:2017-08-19
Release date:2017-11-01
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Mechanism of RNA polymerase II stalling by DNA alkylation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5OQM
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STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Urlaub, H, Cramer, P.
Deposit date:2017-08-13
Release date:2018-05-09
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structures of transcription pre-initiation complex with TFIIH and Mediator.
Nature, 551, 2017

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