4V1M

Architecture of the RNA polymerase II-Mediator core transcription initiation complex

Summary for 4V1M

• Entry DOI: 10.2210/pdb4v1m/pdb
• Related: 4V1N 4V1O
• EMDB information: 2784
• Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4, 5'-D(*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', ... (15 entities in total)
• Functional Keywords: transcription, transcription initiation, rna polymerase ii, general transcription factors
• Biological source: SACCHAROMYCES CEREVISIAE (BAKER'S YEAST); More
• Cellular location: Nucleus: P04050 P08518 P16370 P20434 P20436 P38902; Nucleus, nucleolus : P40422 P27999 P22139; Cytoplasm : P20435
• Total number of polymer chains: 13
• Total formula weight: 481286.62

Authors

Plaschka, C.,Lariviere, L.,Wenzeck, L.,Hemann, M.,Tegunov, D.,Petrotchenko, E.V.,Borchers, C.H.,Baumeister, W.,Herzog, F.,Villa, E.,Cramer, P. (deposition date: 2014-09-29, release date: 2015-02-04, Last modification date: 2017-08-02)

• Primary citation: Plaschka, C.,Lariviere, L.,Wenzeck, L.,Seizl, M.,Hemann, M.,Tegunov, D.,Petrotchenko, E.V.,Borchers, C.H.,Baumeister, W.,Herzog, F.,Villa, E.,Cramer, P.; Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.; Nature, 518:376-, 2015; PubMed: 25652824; DOI: 10.1038/NATURE14229

Experimental method

ELECTRON MICROSCOPY (6.6 Å)