6T9K
 
 | | SAGA Core module | | Descriptor: | Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... | | Authors: | Wang, H, Cheung, A, Cramer, P. | | Deposit date: | 2019-10-28 | | Release date: | 2020-01-29 | | Last modified: | 2020-02-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of the transcription coactivator SAGA.
Nature, 577, 2020
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6T9J
 | | SAGA Tra1 module | | Descriptor: | Transcription factor SPT20, Transcription initiation factor TFIID subunit 12, Transcription-associated protein 1 | | Authors: | Wang, H, Cheung, A, Cramer, P. | | Deposit date: | 2019-10-28 | | Release date: | 2020-01-29 | | Last modified: | 2020-02-19 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of the transcription coactivator SAGA.
Nature, 577, 2020
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6T9I
 | | cryo-EM structure of transcription coactivator SAGA | | Descriptor: | Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... | | Authors: | Wang, H, Cheung, A, Cramer, P. | | Deposit date: | 2019-10-28 | | Release date: | 2020-01-29 | | Last modified: | 2020-02-19 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure of the transcription coactivator SAGA.
Nature, 577, 2020
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7OK0
 | | Cryo-EM structure of the Sulfolobus acidocaldarius RNA polymerase at 2.88 A | | Descriptor: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | | Authors: | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | | Deposit date: | 2021-05-17 | | Release date: | 2021-08-25 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
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7OQ4
 | | Cryo-EM structure of the ATV RNAP Inhibitory Protein (RIP) bound to the DNA-binding channel of the host's RNA polymerase | | Descriptor: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | | Authors: | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | | Deposit date: | 2021-06-02 | | Release date: | 2021-08-25 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
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7OQY
 | | Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA polymerase | | Descriptor: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | | Authors: | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | | Deposit date: | 2021-06-04 | | Release date: | 2021-08-25 | | Last modified: | 2021-11-03 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
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3HOY
 | | Complete RNA polymerase II elongation complex VI | | Descriptor: | 5'-D(*CP*CP*AP*AP*GP*CP*TP*CP*AP*AP*G*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*TP*AP*CP*TP*AP*GP*TP*AP*CP*TP*GP*CP*C)-3', 5'-D(*CP*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*AP*GP*TP*AP*AP*AP*CP*TP*AP*GP*TP*AP*TP*T*GP*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP*T)-3', 5'-R(*UP*AP*UP*AP*UP*GP*CP*A*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*A)-3', ... | | Authors: | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | | Deposit date: | 2009-06-03 | | Release date: | 2009-07-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
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3HOU
 | | Complete RNA polymerase II elongation complex I with a T-U mismatch | | Descriptor: | 5'-D(*A*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*CP*A*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*U*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*U)-3', ... | | Authors: | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | | Deposit date: | 2009-06-03 | | Release date: | 2009-07-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
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4BOC
 | | Structure of mitochondrial RNA polymerase elongation complex | | Descriptor: | 5'-D(*CP*AP*TP*GP*GP*GP*GP*TP*AP*AP*TP*TP*AP*TP *TP*TP*CP*GP*AP*CP*GP*CP*CP*AP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*TP*GP*GP*CP*GP*TP*GP*CP*GP*CP *GP*CP*CP*GP*CP*TP*AP*CP*CP*CP*CP*AP*TP*G)-3', 5'-R(*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP)-3', ... | | Authors: | Schwinghammer, K, Cheung, A, Morozov, Y, Agaronyan, K, Temiakov, D, Cramer, P. | | Deposit date: | 2013-05-18 | | Release date: | 2013-09-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of Human Mitochondrial RNA Polymerase Elongation Complex
Nat.Struct.Mol.Biol., 20, 2013
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5CE7
 | | Structure of a non-canonical CID of Ctk3 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CTD kinase subunit gamma | | Authors: | Muehlbacher, W, Mayer, A, Sun, M, Remmert, M, Cheung, A.C, Niesser, J, Soeding, J, Cramer, P. | | Deposit date: | 2015-07-06 | | Release date: | 2015-08-05 | | Last modified: | 2015-09-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a noncanonical CTD-interacting domain fold.
Proteins, 83, 2015
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3HOV
 | | Complete RNA polymerase II elongation complex II | | Descriptor: | 5'-D(*AP*GP*CP*TP*CP*AP*A*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*T*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', ... | | Authors: | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | | Deposit date: | 2009-06-03 | | Release date: | 2009-07-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
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3HOW
 | | Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine | | Descriptor: | 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... | | Authors: | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | | Deposit date: | 2009-06-03 | | Release date: | 2009-07-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
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3HOZ
 | | Complete RNA polymerase II elongation complex IV with a T-U mismatch and a frayed RNA 3'-guanine | | Descriptor: | 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*CP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*G)-3', ... | | Authors: | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | | Deposit date: | 2009-06-03 | | Release date: | 2009-07-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.65 Å) | | Cite: | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
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3HOX
 | | Complete RNA polymerase II elongation complex V | | Descriptor: | 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*AP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... | | Authors: | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | | Deposit date: | 2009-06-03 | | Release date: | 2009-07-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.65 Å) | | Cite: | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
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4C2M
 | | Structure of RNA polymerase I at 2.8 A resolution | | Descriptor: | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... | | Authors: | Engel, C, Sainsbury, S, Cheung, A.C, Kostrewa, D, Cramer, P. | | Deposit date: | 2013-08-19 | | Release date: | 2013-10-23 | | Last modified: | 2015-08-19 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | RNA Polymerase I Structure and Transcription Regulation.
Nature, 502, 2013
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3TJ1
 | | Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3 | | Descriptor: | RNA polymerase I-specific transcription initiation factor RRN3 | | Authors: | Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P. | | Deposit date: | 2011-08-23 | | Release date: | 2011-09-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
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4A93
 | | RNA Polymerase II elongation complex containing a CPD Lesion | | Descriptor: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ... | | Authors: | Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M. | | Deposit date: | 2011-11-23 | | Release date: | 2012-03-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
Mol.Cell, 46, 2012
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