8PV5
 
 | | Chaetomium thermophilum pre-60S State 8 - pre-5S rotation without Foot - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8PV1
 | | Chaetomium thermophilum pre-60S State 6 - pre-5S rotation - L1 intermediate - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.56 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8PV2
 | | Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1 | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.63 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8PVL
 | | Chaetomium thermophilum pre-60S State 7 - pre-5S rotation lacking Utp30/ITS2 - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-12-06 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.19 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8PVK
 | | Chaetomium thermophilum pre-60S State 5 - pre-5S rotation - L1 inward - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-12-06 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.55 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8PV8
 | | Chaetomium thermophilum pre-60S State 4 - post-5S rotation with Rix1 complex without Foot - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2024-01-10 | | Last modified: | 2024-01-17 | | Method: | ELECTRON MICROSCOPY (2.91 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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6EZ8
 | | Human Huntingtin-HAP40 complex structure | | Descriptor: | Factor VIII intron 22 protein, Huntingtin | | Authors: | Guo, Q, Bin, H, Cheng, J, Pfeifer, G, Baumeister, W, Fernandez-Busnadiego, R, Kochanek, S. | | Deposit date: | 2017-11-14 | | Release date: | 2018-02-21 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | The cryo-electron microscopy structure of huntingtin.
Nature, 555, 2018
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5ZR1
 | | Saccharomyces Cerevisiae Origin Recognition Complex Bound to a 72-bp Origin DNA containing ACS and B1 element | | Descriptor: | 72bp-oring DNA, ACS305, A-rich, ... | | Authors: | Li, N, Lam, W.H, Zhai, Y, Cheng, J, Cheng, E, Zhao, Y, Gao, N, Tye, B.K. | | Deposit date: | 2018-04-21 | | Release date: | 2018-07-11 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure of the origin recognition complex bound to DNA replication origin.
Nature, 559, 2018
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6G4S
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State B | | Descriptor: | 40S ribosomal protein S11, 40S ribosomal protein S13, 40S ribosomal protein S14, ... | | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | Deposit date: | 2018-03-28 | | Release date: | 2018-06-06 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
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6G5H
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | Deposit date: | 2018-03-29 | | Release date: | 2018-06-06 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
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6G4W
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State A | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | Deposit date: | 2018-03-28 | | Release date: | 2018-06-06 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
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6G51
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State D | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | Deposit date: | 2018-03-28 | | Release date: | 2018-06-06 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
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4I8Y
 | | Structure of the unliganded N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus | | Descriptor: | 1-phosphatidylinositol phosphodiesterase, ACETATE ION, CHLORIDE ION | | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. | | Deposit date: | 2012-12-04 | | Release date: | 2013-04-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem., 288, 2013
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4I9J
 | | Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus bound to diC4PC | | Descriptor: | (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, 1-phosphatidylinositol phosphodiesterase, ACETATE ION | | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. | | Deposit date: | 2012-12-05 | | Release date: | 2013-04-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem., 288, 2013
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4I90
 | | Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus bound to choline | | Descriptor: | 1-phosphatidylinositol phosphodiesterase, ACETATE ION, CHLORIDE ION, ... | | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. | | Deposit date: | 2012-12-04 | | Release date: | 2013-04-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem., 288, 2013
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4I9M
 | | Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus bound to HEPES | | Descriptor: | 1-phosphatidylinositol phosphodiesterase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION | | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. | | Deposit date: | 2012-12-05 | | Release date: | 2013-04-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem., 288, 2013
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3V16
 | | An intramolecular pi-cation latch in phosphatidylinositol-specific phospholipase C from S.aureus controls substrate access to the active site | | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, CHLORIDE ION | | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | | Deposit date: | 2011-12-09 | | Release date: | 2012-04-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop
Biochemistry, 51, 2012
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3V18
 | | Structure of the Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | | Descriptor: | 1-phosphatidylinositol phosphodiesterase, ISOPROPYL ALCOHOL, SULFATE ION | | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | | Deposit date: | 2011-12-09 | | Release date: | 2012-04-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop
Biochemistry, 51, 2012
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4I9T
 | | Structure of the H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, SULFATE ION, ... | | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. | | Deposit date: | 2012-12-05 | | Release date: | 2013-04-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The cation-pi box is a specific phosphatidylcholine membrane targeting motif.
J.Biol.Chem., 288, 2013
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4NM6
 | | Crystal structure of TET2-DNA complex | | Descriptor: | 5'-D(*AP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*T)-3', FE (II) ION, Methylcytosine dioxygenase TET2, ... | | Authors: | Hu, L, Li, Z, Cheng, J, Rao, Q, Gong, W, Liu, M, Wang, P, Xu, Y. | | Deposit date: | 2013-11-14 | | Release date: | 2013-12-18 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.026 Å) | | Cite: | Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation.
Cell(Cambridge,Mass.), 155, 2013
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3V1H
 | | Structure of the H258Y mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, ACETATE ION | | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | | Deposit date: | 2011-12-09 | | Release date: | 2012-04-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop
Biochemistry, 51, 2012
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8I9T
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-1 | | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | Deposit date: | 2023-02-07 | | Release date: | 2023-05-17 | | Last modified: | 2023-07-19 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8IA0
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Puf6 | | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | Deposit date: | 2023-02-07 | | Release date: | 2023-05-17 | | Last modified: | 2023-07-19 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9Y
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-2 | | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | Deposit date: | 2023-02-07 | | Release date: | 2023-05-17 | | Last modified: | 2023-07-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9W
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Dbp10-3 | | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | Deposit date: | 2023-02-07 | | Release date: | 2023-05-17 | | Last modified: | 2023-07-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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