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PDB: 103 results

2C9A
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BU of 2c9a by Molmil
Crystal structure of the MAM-Ig module of receptor protein tyrosine phosphatase mu
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU, ...
Authors:Aricescu, A.R, Hon, W.C, Siebold, C, Lu, W, Van Der Merwe, P.A, Jones, E.Y.
Deposit date:2005-12-09
Release date:2006-01-19
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Analysis of Receptor Protein Tyrosine Phosphatase Mu-Mediated Cell Adhesion.
Embo J., 25, 2006
2V5Y
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BU of 2v5y by Molmil
Crystal structure of the receptor protein tyrosine phosphatase mu ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU, SODIUM ION
Authors:Aricescu, A.R, Siebold, C, Choudhuri, K, Chang, V.T, Lu, W, Davis, S.J, van der Merwe, P.A, Jones, E.Y.
Deposit date:2007-07-11
Release date:2007-09-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a Tyrosine Phosphatase Adhesive Interaction Reveals a Spacer-Clamp Mechanism.
Science, 317, 2007
5OJ6
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BU of 5oj6 by Molmil
Crystal structure of the chicken MDGA1 ectodomain in complex with the human neuroligin 1 (NL1(-A-B)) cholinesterase domain.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAM domain-containing glycosylphosphatidylinositol anchor protein 1, Neuroligin-1, ...
Authors:Elegheert, J, Clayton, A.J, Aricescu, A.R.
Deposit date:2017-07-20
Release date:2017-08-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins.
Neuron, 95, 2017
5OJ2
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BU of 5oj2 by Molmil
Crystal structure of the chicken MDGA1 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAM domain-containing glycosylphosphatidylinositol anchor protein 1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Elegheert, J, Clayton, A.J, Aricescu, A.R.
Deposit date:2017-07-20
Release date:2017-08-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins.
Neuron, 95, 2017
1JLN
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BU of 1jln by Molmil
Crystal structure of the catalytic domain of protein tyrosine phosphatase PTP-SL/BR7
Descriptor: Protein Tyrosine Phosphatase, receptor type, R
Authors:Szedlacsek, S.E, Aricescu, A.R, Fulga, T.A, Renault, L, Scheidig, A.J.
Deposit date:2001-07-16
Release date:2001-08-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure of PTP-SL/PTPBR7 catalytic domain: implications for MAP kinase regulation.
J.Mol.Biol., 311, 2001
9EQG
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BU of 9eqg by Molmil
CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with GABA and puerarin
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kasaragod, V.B, Aricescu, A.R.
Deposit date:2024-03-21
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:A brain-to-gut signal controls intestinal fat absorption.
Nature, 2024
6YPE
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Crystal structure of the human neuronal pentraxin 1 (NP1) pentraxin (PTX) domain.
Descriptor: CACODYLATE ION, CALCIUM ION, Neuronal pentraxin-1
Authors:Elegheert, J, Clayton, A.J, Aricescu, A.R.
Deposit date:2020-04-15
Release date:2020-06-03
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:A synthetic synaptic organizer protein restores glutamatergic neuronal circuits.
Science, 369, 2020
6QD6
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BU of 6qd6 by Molmil
Molecular scaffolds expand the nanobody toolkit for cryo-EM applications: crystal structure of Mb-cHopQ-Nb207
Descriptor: CHLORIDE ION, Mb-cHopQ-Nb207,Outer membrane protein,Mb-cHopQ-Nb207,Outer membrane protein,Mb-cHopQ-Nb207
Authors:Uchanski, T, Masiulis, S, Fischer, B, Kalichuk, V, Wohlkonig, A, Zogg, T, Remaut, H, Vranken, W, Aricescu, A.R, Pardon, E, Steyaert, J.
Deposit date:2018-12-31
Release date:2019-12-18
Last modified:2021-01-13
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM
Nat.Methods, 18, 2021
6QFA
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BU of 6qfa by Molmil
CryoEM structure of a beta3K279T GABA(A)R homomer in complex with histamine and megabody Mb25
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit beta-3,Gamma-aminobutyric acid receptor subunit beta-3, HISTAMINE, ...
Authors:Uchanski, T, Masiulis, S, Fischer, B, Kalichuk, V, Wohlkoening, A, Zoegg, T, Remaut, H, Vranken, W, Aricescu, A.R, Pardon, E, Steyaert, J.
Deposit date:2019-01-09
Release date:2021-08-04
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.49 Å)
Cite:Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Nat.Methods, 18, 2021
3SUA
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BU of 3sua by Molmil
Crystal structure of the intracellular domain of Plexin-B1 in complex with Rac1
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-B1, ...
Authors:Bell, C.H, Aricescu, A.R, Jones, E.Y, Siebold, C.
Deposit date:2011-07-11
Release date:2011-09-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.39 Å)
Cite:A Dual Binding Mode for RhoGTPases in Plexin Signalling.
Plos Biol., 9, 2011
3SU8
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BU of 3su8 by Molmil
Crystal structure of a truncated intracellular domain of Plexin-B1 in complex with Rac1
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-B1, ...
Authors:Bell, C.H, Aricescu, A.R, Jones, E.Y, Siebold, C.
Deposit date:2011-07-11
Release date:2011-09-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A Dual Binding Mode for RhoGTPases in Plexin Signalling.
Plos Biol., 9, 2011
2CME
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BU of 2cme by Molmil
The crystal structure of SARS coronavirus ORF-9b protein
Descriptor: DECANE, HYPOTHETICAL PROTEIN 5
Authors:Meier, C, Aricescu, A.R, Assenberg, R, Aplin, R.T, Gilbert, R.J.C, Grimes, J.M, Stuart, D.I.
Deposit date:2006-05-06
Release date:2006-07-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structure of Orf-9B, a Lipid Binding Protein from the Sars Coronavirus.
Structure, 14, 2006
5O8F
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BU of 5o8f by Molmil
Structure of a chimaeric beta3-alpha5 GABAA receptor in complex with nanobody Nb25 and pregnanolone
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit beta-3,Gamma-aminobutyric acid receptor subunit alpha-5,Gamma-aminobutyric acid receptor subunit alpha-5, Nanobody Nb25, ...
Authors:Miller, P.S, Scott, S, Masiulis, S, De Colibus, L, Pardon, E, Steyaert, J, Aricescu, A.R.
Deposit date:2017-06-13
Release date:2017-11-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for GABAA receptor potentiation by neurosteroids.
Nat. Struct. Mol. Biol., 24, 2017
5OJK
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BU of 5ojk by Molmil
Crystal structure of the human neuroligin 1 cholinesterase domain containing spliced sequence B (SSB) (NL1(-A+B))
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-1,Neuroligin-1, TRIETHYLENE GLYCOL
Authors:Elegheert, J, Aricescu, A.R.
Deposit date:2017-07-21
Release date:2017-08-23
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins.
Neuron, 95, 2017
5OJM
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BU of 5ojm by Molmil
Structure of a chimaeric beta3-alpha5 GABAA receptor in complex with nanobody Nb25
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Human GABAA receptor chimera beta3-alpha5,Gamma-aminobutyric acid receptor subunit beta-3,Gamma-aminobutyric acid receptor subunit alpha-5, Nanobody Nb25, ...
Authors:Miller, P.S, Scott, S, Masiulis, S, De Colibus, L, Pardon, E, Steyaert, J, Aricescu, A.R.
Deposit date:2017-07-21
Release date:2017-10-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for GABAA receptor potentiation by neurosteroids.
Nat. Struct. Mol. Biol., 24, 2017
3ZYI
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BU of 3zyi by Molmil
NetrinG2 in complex with NGL2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4, ...
Authors:Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, McIlhinney, R.A.J, Aricescu, A.R, Jones, E.Y.
Deposit date:2011-08-23
Release date:2011-10-05
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions
Embo J., 30, 2011
3ZYG
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BU of 3zyg by Molmil
NETRING2 LAM AND EGF1 DOMAINS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NETRIN-G2
Authors:Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, Mcilhinney, R.A.J, Aricescu, A.R, Jones, E.Y.
Deposit date:2011-08-22
Release date:2011-10-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions.
Embo J., 30, 2011
3ZYO
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BU of 3zyo by Molmil
Crystal structure of the N-terminal leucine rich repeats and immunoglobulin domain of netrin-G ligand-3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B, ZINC ION
Authors:Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, McIlhinney, R.A.J, Aricescu, A.R, Jones, E.Y.
Deposit date:2011-08-24
Release date:2011-10-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions.
Embo J., 30, 2011
3ZYN
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BU of 3zyn by Molmil
Crystal structure of the N-terminal leucine rich repeats of Netrin-G Ligand-3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B
Authors:Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, McIlhinney, R.A.J, Aricescu, A.R, Jones, E.Y.
Deposit date:2011-08-23
Release date:2011-10-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions.
Embo J., 30, 2011
3ZYJ
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BU of 3zyj by Molmil
NetrinG1 in complex with NGL1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C, ...
Authors:Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, McIlhinney, R.A.J, Aricescu, A.R, Jones, E.Y.
Deposit date:2011-08-23
Release date:2011-10-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions.
Embo J., 30, 2011
5FMV
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BU of 5fmv by Molmil
Crystal structure of human CD45 extracellular region, domains d1-d4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, SULFATE ION
Authors:Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J.
Deposit date:2015-11-09
Release date:2016-03-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
5FN6
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BU of 5fn6 by Molmil
Crystal structure of human CD45 extracellular region, domains d1-d3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C
Authors:Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J.
Deposit date:2015-11-10
Release date:2016-03-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
5FN8
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BU of 5fn8 by Molmil
Crystal structure of rat CD45 extracellular region, domains d3-d4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C
Authors:Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J.
Deposit date:2015-11-11
Release date:2016-03-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
5FN7
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BU of 5fn7 by Molmil
Crystal structure of human CD45 extracellular region, domains d1-d2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C
Authors:Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J.
Deposit date:2015-11-10
Release date:2016-03-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
6I53
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BU of 6i53 by Molmil
Cryo-EM structure of the human synaptic alpha1-beta3-gamma2 GABAA receptor in complex with Megabody38 in a lipid nanodisc
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-1, ...
Authors:Laverty, D, Desai, R, Uchanski, T, Masiulis, S, Wojciech, J.S, Malinauskas, T, Zivanov, J, Pardon, E, Steyaert, J, Miller, K.W, Aricescu, A.R.
Deposit date:2018-11-12
Release date:2019-01-02
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the human alpha 1 beta 3 gamma 2 GABAAreceptor in a lipid bilayer.
Nature, 565, 2019

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