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5K36
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BU of 5k36 by Molmil
Structure of an eleven component nuclear RNA exosome complex bound to RNA
Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
Authors:Lima, C.D, Zinder, J.C.
Deposit date:2016-05-19
Release date:2016-11-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Nuclear RNA Exosome at 3.1 angstrom Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3.
Mol.Cell, 64, 2016
7U5C
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BU of 7u5c by Molmil
Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state
Descriptor: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ...
Authors:Cai, S.W, Zinder, J.C, Svetlov, V, Bush, M.W, Nudler, E, Walz, T, de Lange, T.
Deposit date:2022-03-02
Release date:2022-05-18
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Cryo-EM structure of the human CST-Pol alpha /primase complex in a recruitment state.
Nat.Struct.Mol.Biol., 29, 2022
4WOI
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BU of 4woi by Molmil
4,5-linked aminoglycoside antibiotics regulate the bacterial ribosome by targeting dynamic conformational processes within intersubunit bridge B2
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Pulk, A, Cate, J.H.D, Blanchard, S, Wasserman, M, Altman, R, Zhou, Z, Zinder, J, Green, K, Garneau-Tsodikova, S.
Deposit date:2014-10-15
Release date:2015-08-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions.
Nat Commun, 6, 2015
6D6R
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BU of 6d6r by Molmil
Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction
Descriptor: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ...
Authors:Weick, E.-M, Lima, C.D.
Deposit date:2018-04-22
Release date:2018-06-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.
Cell, 173, 2018
6D6Q
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BU of 6d6q by Molmil
Human nuclear exosome-MTR4 RNA complex - overall reconstruction
Descriptor: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ...
Authors:Weick, E.-M, Lima, C.D.
Deposit date:2018-04-22
Release date:2018-06-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.
Cell, 173, 2018
5VZJ
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BU of 5vzj by Molmil
STRUCTURE OF A TWELVE COMPONENT MPP6-NUCLEAR RNA EXOSOME COMPLEX BOUND TO RNA
Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
Authors:Lima, C.D, Wasmuth, E.V.
Deposit date:2017-05-28
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase.
Elife, 6, 2017

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