4HKF
| Crystal structure of Danio rerio MEC-17 catalytic domain in complex with acetyl-CoA | Descriptor: | ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, SULFATE ION | Authors: | Li, W, Zhong, C, Sun, B, Xu, S, Zhang, T, Ding, J. | Deposit date: | 2012-10-15 | Release date: | 2012-12-12 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular basis of the acetyltransferase activity of MEC-17 towards alpha- tubulin Cell Res., 22, 2012
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3JXE
| Crystal structure of Pyrococcus horikoshii tryptophanyl-tRNA synthetase in complex with TrpAMP | Descriptor: | SULFATE ION, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | Authors: | Zhou, M, Dong, X, Zhong, C, Shen, N, Yang, B, Ding, J. | Deposit date: | 2009-09-19 | Release date: | 2009-11-10 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of P. horikoshii tryptophanyl-tRNA synthetase and structure-based phylogenetic analysis suggest an archaeal origin of tryptophanyl-tRNA synthetase To be Published
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3KT3
| Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase in complex with TrpAMP | Descriptor: | SULFATE ION, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase, ... | Authors: | Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J. | Deposit date: | 2009-11-24 | Release date: | 2010-02-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design Nucleic Acids Res., 38, 2010
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3KT6
| Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase in complex with Trp | Descriptor: | SULFATE ION, TRYPTOPHAN, Tryptophanyl-tRNA synthetase, ... | Authors: | Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J. | Deposit date: | 2009-11-24 | Release date: | 2010-02-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design Nucleic Acids Res., 38, 2010
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3KT0
| Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase | Descriptor: | (2S)-1-{[(2S)-3-(2-methoxyethoxy)-2-methylpropyl]oxy}propan-2-amine, Tryptophanyl-tRNA synthetase, cytoplasmic | Authors: | Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J. | Deposit date: | 2009-11-24 | Release date: | 2010-02-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design Nucleic Acids Res., 38, 2010
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3KT8
| Crystal structure of S. cerevisiae tryptophanyl-tRNA synthetase in complex with L-tryptophanamide | Descriptor: | L-TRYPTOPHANAMIDE, SULFATE ION, Tryptophanyl-tRNA synthetase, ... | Authors: | Zhou, M, Dong, X, Zhong, C, Shen, N, Ding, J. | Deposit date: | 2009-11-24 | Release date: | 2010-02-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design Nucleic Acids Res., 38, 2010
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3NFS
| Crystal structure the Fab fragment of therapeutic antibody daclizumab | Descriptor: | Heavy chain of Fab fragment of daclizumab, Light chain of Fab fragment of daclizumab | Authors: | Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. | Deposit date: | 2010-06-10 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
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3NFP
| Crystal structure of the Fab fragment of therapeutic antibody daclizumab in complex with IL-2Ra (CD25) ectodomain | Descriptor: | Heavy chain of Fab fragment of daclizumab, Interleukin-2 receptor subunit alpha, Light chain of Fab fragment of daclizumab | Authors: | Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. | Deposit date: | 2010-06-10 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
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3CXD
| Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide | Descriptor: | Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ... | Authors: | Du, J, Yang, H, Zhong, C, Ding, J. | Deposit date: | 2008-04-24 | Release date: | 2008-10-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis J.Mol.Biol., 382, 2008
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3DSF
| Crystal structure of anti-osteopontin antibody 23C3 in complex with W43A mutated epitope peptide | Descriptor: | Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ... | Authors: | Du, J, Zhong, C, Yang, H, Ding, J. | Deposit date: | 2008-07-12 | Release date: | 2008-10-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis J.Mol.Biol., 382, 2008
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3EBM
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4L44
| Crystal structures of human p70S6K1-T389A (form II) | Descriptor: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein, SULFATE ION, ... | Authors: | Wang, J, Zhong, C, Ding, J. | Deposit date: | 2013-06-07 | Release date: | 2013-07-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif Biochem.J., 454, 2013
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4L46
| Crystal structures of human p70S6K1-WT | Descriptor: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein, SULFATE ION, ... | Authors: | Wang, J, Zhong, C, Ding, J. | Deposit date: | 2013-06-07 | Release date: | 2013-07-24 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif Biochem.J., 454, 2013
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4L42
| Crystal structures of human p70S6K1-PIF | Descriptor: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein, SULFATE ION, ... | Authors: | Wang, J, Zhong, C, Ding, J. | Deposit date: | 2013-06-07 | Release date: | 2013-07-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif Biochem.J., 454, 2013
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4L45
| Crystal structures of human p70S6K1-T389E | Descriptor: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein | Authors: | Wang, J, Zhong, C, Ding, J. | Deposit date: | 2013-06-07 | Release date: | 2013-07-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif Biochem.J., 454, 2013
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4L3J
| Crystal structures of human p70S6K1 kinase domain | Descriptor: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein, ZINC ION | Authors: | Wang, J, Zhong, C, Ding, J. | Deposit date: | 2013-06-06 | Release date: | 2013-07-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif Biochem.J., 454, 2013
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4L43
| Crystal structures of human p70S6K1-T389A (form I) | Descriptor: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein | Authors: | Wang, J, Zhong, C, Ding, J. | Deposit date: | 2013-06-07 | Release date: | 2013-07-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif Biochem.J., 454, 2013
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4L3L
| Crystal structures of human p70S6K1 kinase domain (Zinc anomalous) | Descriptor: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein, ZINC ION | Authors: | Wang, J, Zhong, C, Ding, J. | Deposit date: | 2013-06-06 | Release date: | 2013-07-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif Biochem.J., 454, 2013
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4FGB
| Crystal structure of human calcium/calmodulin-dependent protein kinase I apo form | Descriptor: | Calcium/calmodulin-dependent protein kinase type 1 | Authors: | Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J. | Deposit date: | 2012-06-04 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI. Plos One, 7, 2012
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4FG9
| Crystal structure of human calcium/calmodulin-dependent protein kinase I 1-320 in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type 1 | Authors: | Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J. | Deposit date: | 2012-06-04 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI. Plos One, 7, 2012
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4FG8
| Crystal structure of human calcium/calmodulin-dependent protein kinase I 1-315 in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type 1 | Authors: | Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J. | Deposit date: | 2012-06-04 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI. Plos One, 7, 2012
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4FG7
| Crystal structure of human calcium/calmodulin-dependent protein kinase I 1-293 in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type 1 | Authors: | Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J. | Deposit date: | 2012-06-04 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI. Plos One, 7, 2012
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7WOI
| Structure of the shaft pilin Spa2 from Corynebacterium glutamicum | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Spa2 | Authors: | Wu, Y.F, Wang, L.T, Huang, Y.Y, Zhong, C, Zhou, J. | Deposit date: | 2022-01-21 | Release date: | 2023-01-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Accelerating the design of pili-enabled living materials using an integrative technological workflow. Nat.Chem.Biol., 2023
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4LMQ
| Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12 | Descriptor: | Stromal cell-derived factor 1, hu30D8 Fab heavy chain, hu30D8 Fab light chain | Authors: | Zhong, Z, Wang, J, Li, B, Xiang, H, Ultsch, M, Coons, M, Wong, T, Chiang, N.Y, Clark, S, Clark, R, Quintana, L, Gribling, P, Suto, E, Barck, K, Corpuz, R, Yao, J, Takkar, R, Lee, W.P, Damico-Beyer, L.A, Carano, R.D, Adams, C, Kelley, R.F, Wang, W, Ferrara, N. | Deposit date: | 2013-07-10 | Release date: | 2013-08-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.773 Å) | Cite: | Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12. Clin.Cancer Res., 19, 2013
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2QFY
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