7B05
 
 | | TRPC4 in complex with inhibitor GFB-8749 | | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 4-[4-[[4,4-bis(fluoranyl)cyclohexyl]methyl]-3-oxidanylidene-piperazin-1-yl]-5-chloranyl-1~{H}-pyridazin-6-one, CALCIUM ION, ... | | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | | Deposit date: | 2020-11-18 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
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4X1U
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4X0X
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7FCQ
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7FCP
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7DNH
 | | 2-fold subparticles refinement of human papillomavirus type 58 pseudovirus in complexed with the Fab fragment of 2H3 | | Descriptor: | Major capsid protein L1, The heavy chain of 2H3 Fab fragment, The light chain of 2H3 Fab fragment | | Authors: | He, M.Z, Chi, X, Zha, Z.H, Zheng, Q.B, Gu, Y, Li, S.W, Xia, N.S. | | Deposit date: | 2020-12-09 | | Release date: | 2020-12-30 | | Last modified: | 2022-12-07 | | Method: | ELECTRON MICROSCOPY (3.64 Å) | | Cite: | Structural basis for the shared neutralization mechanism of three classes of human papillomavirus type 58 antibodies with disparate modes of binding.
J.Virol., 95, 2021
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7DNK
 | | 2-fold subparticles refinement of human papillomavirus type 58 pseudovirus in complexed with the Fab fragment of 5G9 | | Descriptor: | Major capsid protein L1, The heavy chain of 5G9 Fab fragment, The light chain of 5G9 Fab fragment | | Authors: | He, M.Z, Chi, X, Zha, Z.H, Zheng, Q.B, Gu, Y, Li, S.W, Xia, N.S. | | Deposit date: | 2020-12-09 | | Release date: | 2020-12-30 | | Last modified: | 2022-12-07 | | Method: | ELECTRON MICROSCOPY (6.41 Å) | | Cite: | Structural basis for the shared neutralization mechanism of three classes of human papillomavirus type 58 antibodies with disparate modes of binding.
J.Virol., 95, 2021
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7DNL
 | | 2-fold subparticles refinement of human papillomavirus type 58 pseudovirus in complexed with the Fab fragment of A4B4 | | Descriptor: | Major capsid protein L1, The heavy chain of 2H3 Fab fragment, The light chain of A4B4 Fab fragment | | Authors: | He, M.Z, Chi, X, Zha, Z.H, Zheng, Q.B, Gu, Y, Li, S.W, Xia, N.S. | | Deposit date: | 2020-12-09 | | Release date: | 2020-12-30 | | Last modified: | 2022-12-07 | | Method: | ELECTRON MICROSCOPY (4.19 Å) | | Cite: | Structural basis for the shared neutralization mechanism of three classes of human papillomavirus type 58 antibodies with disparate modes of binding.
J.Virol., 95, 2021
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7DZL
 | | A69C-M71L mutant of Fabp protein | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZF
 | | Intermediate of FABP with a delay time of 10 ns | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZJ
 | | Fabp protein before hv | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZH
 | | intermediate of FABP with a delay time of 100 ns | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZG
 | | Intermediate of FABP with a delay time of 30 ns | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZE
 | | Fabp ground state captured by XFELs | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZI
 | | intermediate of FABP with a delay time of 300 ns | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZK
 | | Fabp protein after hv | | Descriptor: | Fatty acid-binding protein, liver, PALMITIC ACID | | Authors: | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | Deposit date: | 2021-01-25 | | Release date: | 2022-07-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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5YEU
 | | Structural and mechanistic analyses reveal a unique Cas4-like protein in the mimivirus virophage resistance element system | | Descriptor: | MAGNESIUM ION, Uncharacterized protein R354 | | Authors: | Dou, C, Yu, M.J, Gu, Y.J, Cheng, W. | | Deposit date: | 2017-09-19 | | Release date: | 2018-07-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.001 Å) | | Cite: | Structural and Mechanistic Analyses Reveal a Unique Cas4-like Protein in the Mimivirus Virophage Resistance Element System.
Iscience, 3, 2018
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5YET
 | | Structure of R354_WT | | Descriptor: | Uncharacterized protein R354 | | Authors: | Dou, C, Yu, M.J, Gu, Y.J, Cheng, W. | | Deposit date: | 2017-09-19 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.806 Å) | | Cite: | Structural and Mechanistic Analyses Reveal a Unique Cas4-like Protein in the Mimivirus Virophage Resistance Element System.
Iscience, 3, 2018
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6EWH
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3U0J
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2FR2
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6TWN
 | | Crystal structure of Talin1 R7R8 in complex with CDK1 (206-223) | | Descriptor: | CHLORIDE ION, Cyclin-dependent kinase 1, GLYCEROL, ... | | Authors: | Zacharchenko, T, Muench, S.P, Goult, B.T. | | Deposit date: | 2020-01-13 | | Release date: | 2021-05-12 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1.
J.Biol.Chem., 297, 2021
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3IOS
 | | Structure of MTB dsbF in its mixed oxidized and reduced forms | | Descriptor: | Disulfide bond forming protein (DsbF) | | Authors: | Chim, N, Goulding, C.W. | | Deposit date: | 2009-08-14 | | Release date: | 2010-01-05 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | An extracellular disulfide bond forming protein (DsbF) from Mycobacterium tuberculosis: structural, biochemical, and gene expression analysis.
J.Mol.Biol., 396, 2010
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6NZV
 | | Crystal structure of HCV NS3/4A protease in complex with compound 12 | | Descriptor: | (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide, HCV NS3/4A protease, SULFATE ION, ... | | Authors: | Appleby, T.C, Taylor, J.G. | | Deposit date: | 2019-02-14 | | Release date: | 2019-07-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®.
Bioorg.Med.Chem.Lett., 29, 2019
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8EL8
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