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4OLX
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BU of 4olx by Molmil
Crystal structure of antibody VRC07-G54L in complex with clade A/E 93TH057 HIV-1 gp120 core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ...
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2014-01-25
Release date:2014-09-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo.
J.Virol., 88, 2014
3NGB
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BU of 3ngb by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 gp120
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2010-06-11
Release date:2010-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.
Science, 329, 2010
4I3R
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BU of 4i3r by Molmil
Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P3221
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ...
Authors:Joyce, M.G, Biertumpfel, C, Nabel, G.J, Kwong, P.D.
Deposit date:2012-11-26
Release date:2013-01-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04.
J.Virol., 87, 2013
4I3S
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BU of 4i3s by Molmil
Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P21
Descriptor: CALCIUM ION, Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ...
Authors:Joyce, M.G, Biertumpfel, C, Nabel, G.J, Kwong, P.D.
Deposit date:2012-11-26
Release date:2013-01-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04.
J.Virol., 87, 2013
4ZPV
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BU of 4zpv by Molmil
Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, D12 Fab Heavy chain, D12 Fab light chain, ...
Authors:Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
Deposit date:2015-05-08
Release date:2015-10-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Evaluation of candidate vaccine approaches for MERS-CoV.
Nat Commun, 6, 2015
4ZPW
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BU of 4zpw by Molmil
Structure of unbound MERS-CoV spike receptor-binding domain (England1 strain).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Spike glycoprotein
Authors:Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
Deposit date:2015-05-08
Release date:2015-08-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.023 Å)
Cite:Evaluation of candidate vaccine approaches for MERS-CoV.
Nat Commun, 6, 2015
4HQQ
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BU of 4hqq by Molmil
Crystal structure of RV144-elicited antibody CH58
Descriptor: CH58 Fab heavy chain, CH58 Fab light chain
Authors:McLellan, J.S, Haynes, B.F, Kwong, P.D.
Deposit date:2012-10-25
Release date:2013-02-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4HPO
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BU of 4hpo by Molmil
Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide
Descriptor: CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ...
Authors:McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
Deposit date:2012-10-24
Release date:2013-02-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.694 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4HPY
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BU of 4hpy by Molmil
Crystal structure of RV144-elicited antibody CH59 in complex with V2 peptide
Descriptor: CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ...
Authors:McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
Deposit date:2012-10-24
Release date:2013-02-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
6KRG
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BU of 6krg by Molmil
Crystal structure of sfGFP Y182TMSiPhe
Descriptor: CHLORIDE ION, GLYCEROL, Green fluorescent protein, ...
Authors:Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P.
Deposit date:2019-08-21
Release date:2020-09-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe.
Nat Commun, 11, 2020
2I4X
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BU of 2i4x by Molmil
HIV-1 Protease I84V, L90M with GS-8374
Descriptor: DIETHYL ({4-[(2S,3R)-2-({[(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YLOXY]CARBONYL}AMINO)-3-HYDROXY-4-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}BUTYL]PHENOXY}METHYL)PHOSPHONATE, Protease
Authors:Hatada, M.
Deposit date:2006-08-22
Release date:2007-08-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Suppression of HIV-1 Protease Inhibitor Resistance by Phosphonate-mediated Solvent Anchoring.
J.Mol.Biol., 363, 2006
2I4W
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BU of 2i4w by Molmil
HIV-1 protease WT with GS-8374
Descriptor: DIETHYL ({4-[(2S,3R)-2-({[(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YLOXY]CARBONYL}AMINO)-3-HYDROXY-4-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}BUTYL]PHENOXY}METHYL)PHOSPHONATE, Protease
Authors:Hatada, M.
Deposit date:2006-08-22
Release date:2007-08-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Suppression of HIV-1 Protease Inhibitor Resistance by Phosphonate-mediated Solvent Anchoring.
J.Mol.Biol., 363, 2006
2I4U
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BU of 2i4u by Molmil
HIV-1 protease with TMC-126
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL [(1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL]CARBAMATE, Protease
Authors:Hatada, M.
Deposit date:2006-08-22
Release date:2007-08-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Suppression of HIV-1 Protease Inhibitor Resistance by Phosphonate-mediated Solvent Anchoring.
J.Mol.Biol., 363, 2006
2I4D
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BU of 2i4d by Molmil
Crystal structure of WT HIV-1 protease with GS-8373
Descriptor: ({4-[(2S,3R)-2-({[(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YLOXY]CARBONYL}AMINO)-3-HYDROXY-4-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}BUTYL]PHENOXY}METHYL)PHOSPHONIC ACID, Protease
Authors:Hatada, M.
Deposit date:2006-08-21
Release date:2007-08-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Suppression of HIV-1 Protease Inhibitor Resistance by Phosphonate-mediated Solvent Anchoring.
J.Mol.Biol., 363, 2006
2I4V
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BU of 2i4v by Molmil
HIV-1 protease I84V, L90M with TMC126
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL [(1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL]CARBAMATE, Protease
Authors:Hatada, M.
Deposit date:2006-08-22
Release date:2007-08-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Suppression of HIV-1 Protease Inhibitor Resistance by Phosphonate-mediated Solvent Anchoring.
J.Mol.Biol., 363, 2006
7CKG
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BU of 7ckg by Molmil
Crystal structure of TMSiPheRS complexed with TMSiPhe
Descriptor: 4-(trimethylsilyl)-L-phenylalanine, Tyrosine--tRNA ligase
Authors:Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P.
Deposit date:2020-07-17
Release date:2021-03-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.053 Å)
Cite:DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe.
Nat Commun, 11, 2020
7CKH
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BU of 7ckh by Molmil
Crystal structure of TMSiPheRS
Descriptor: Tyrosine--tRNA ligase
Authors:Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P.
Deposit date:2020-07-17
Release date:2021-03-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.79492676 Å)
Cite:DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe.
Nat Commun, 11, 2020
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