5Y50
| Crystal structure of eukaryotic MATE transporter AtDTX14 | Descriptor: | Protein DETOXIFICATION 14 | Authors: | Miyauchi, H, Kusakizako, T, Nishizawa, T, Ishitani, R, Nureki, O. | Deposit date: | 2017-08-06 | Release date: | 2017-12-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for xenobiotic extrusion by eukaryotic MATE transporter Nat Commun, 8, 2017
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6AK3
| Crystal structure of the human prostaglandin E receptor EP3 bound to prostaglandin E2 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Prostaglandin E2 receptor EP3 subtype,Soluble cytochrome b562 | Authors: | Morimoto, K, Suno, R, Iwata, S, Kobayashi, T. | Deposit date: | 2018-08-29 | Release date: | 2018-12-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the endogenous agonist-bound prostanoid receptor EP3. Nat. Chem. Biol., 15, 2019
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7XJH
| Isoproterenol-activated dog beta3 adrenergic receptor | Descriptor: | Beta-3 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Shihoya, W, Nureki, O. | Deposit date: | 2022-04-18 | Release date: | 2022-05-04 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of the beta 3-adrenergic receptor reveals the molecular basis of subtype selectivity. Mol.Cell, 81, 2021
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5H9V
| Crystal structure of Regnase PIN domain, form I | Descriptor: | Ribonuclease ZC3H12A, SODIUM ION | Authors: | Yokogawa, M, Tsushima, T, Adachi, W, Noda, N.N, Inagaki, F. | Deposit date: | 2015-12-29 | Release date: | 2016-03-16 | Last modified: | 2020-02-19 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural basis for the regulation of enzymatic activity of Regnase-1 by domain-domain interactions Sci Rep, 6, 2016
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5H9W
| Crystal structure of Regnase PIN domain, form II | Descriptor: | Ribonuclease ZC3H12A, SODIUM ION | Authors: | Yokogawa, M, Tsushima, T, Adachi, W, Noda, N.N, Inagaki, F. | Deposit date: | 2015-12-29 | Release date: | 2016-03-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the regulation of enzymatic activity of Regnase-1 by domain-domain interactions Sci Rep, 6, 2016
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5XSZ
| Crystal structure of zebrafish lysophosphatidic acid receptor LPA6 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Lysophosphatidic acid receptor 6a,Endolysin,Lysophosphatidic acid receptor 6a | Authors: | Taniguchi, R, Nishizawa, T, Ishitani, R, Nureki, O. | Deposit date: | 2017-06-16 | Release date: | 2017-08-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6 Nature, 548, 2017
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5ZLG
| Human duodenal cytochrome b (Dcytb) in zinc ion and ascorbate bound form | Descriptor: | ASCORBIC ACID, Cytochrome b reductase 1, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Ganasen, M, Togashi, H, Mauk, G.A, Shiro, Y, Sawai, H, Sugimoto, H. | Deposit date: | 2018-03-27 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate. Commun Biol, 1, 2018
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5ZLE
| Human duodenal cytochrome b (Dcytb) in substrate free form | Descriptor: | Cytochrome b reductase 1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Ganasen, M, Togashi, H, Mauk, G.A, Shiro, Y, Sawai, H, Sugimoto, H. | Deposit date: | 2018-03-27 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate. Commun Biol, 1, 2018
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7F47
| Cryo-EM structure of Rhizobium etli MprF | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Hypothetical conserved protein, [(2R)-1-[[(2R)-3-[(2S)-2,6-bis(azanyl)hexanoyl]oxy-2-oxidanyl-propoxy]-oxidanyl-phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (E)-octadec-9-enoate | Authors: | Nishimura, M, Hirano, H, Kobayashi, K, Gill, C.P, Phan, C.N.K, Kise, Y, Kusakizako, T, Yamashita, K, Ito, Y, Roy, H, Nishizawa, T, Nureki, O. | Deposit date: | 2021-06-17 | Release date: | 2022-06-22 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structure of Rhizobium etli MprF To Be Published
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8JHH
| Glycoside hydrolase family 55 endo-beta-1,3-glucanase from Microdochium nivale | Descriptor: | GLYCEROL, MnLam55A | Authors: | Ota, T, Saburi, W, Yamashita, K, Tagami, T, Yu, J, Komba, S, Jewell, L.E, Hsiang, T, Imai, R, Yao, M, Mori, H. | Deposit date: | 2023-05-23 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular mechanism for endo-type action of glycoside hydrolase family 55 endo-beta-1,3-glucanase on beta 1-3/1-6-glucan. J.Biol.Chem., 299, 2023
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7A4M
| Cryo-EM structure of mouse heavy-chain apoferritin at 1.22 A | Descriptor: | FE (III) ION, Ferritin heavy chain, ZINC ION | Authors: | Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W. | Deposit date: | 2020-08-20 | Release date: | 2020-10-28 | Last modified: | 2023-06-21 | Method: | ELECTRON MICROSCOPY (1.22 Å) | Cite: | Single-particle cryo-EM at atomic resolution. Nature, 587, 2020
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7A5V
| CryoEM structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer, in complex with histamine and megabody Mb25 in lipid nanodisc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W. | Deposit date: | 2020-08-22 | Release date: | 2020-11-18 | Last modified: | 2020-11-25 | Method: | ELECTRON MICROSCOPY (1.7 Å) | Cite: | Single-particle cryo-EM at atomic resolution. Nature, 587, 2020
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7DY0
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7EFD
| 1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40 e/A^2 total dose) | Descriptor: | BIOTIN, Streptavidin | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O. | Deposit date: | 2021-03-21 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (1.77 Å) | Cite: | 1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40e/A^2 total dose) To Be Published
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7EFC
| 1.70 A cryo-EM structure of streptavidin | Descriptor: | BIOTIN, Streptavidin | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O. | Deposit date: | 2021-03-21 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (1.7 Å) | Cite: | 1.70 A cryo-EM structure of streptavidin using all frames (corresponding to 70 e/A^2 total dose) To Be Published
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7V6B
| Structure of the Dicer-2-R2D2 heterodimer | Descriptor: | Dicer-2, isoform A, R2D2 | Authors: | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | Deposit date: | 2021-08-20 | Release date: | 2022-03-23 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature, 607, 2022
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7V6C
| Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex | Descriptor: | Dicer-2, isoform A, R2D2, ... | Authors: | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | Deposit date: | 2021-08-20 | Release date: | 2022-03-23 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature, 607, 2022
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