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2FVU
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BU of 2fvu by Molmil
Structure of the yeast Sir3 BAH domain
Descriptor: Regulatory protein SIR3
Authors:Xu, R.M.
Deposit date:2006-01-31
Release date:2006-09-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of the Saccharomyces cerevisiae Sir3 BAH domain.
Mol.Cell.Biol., 26, 2006
2H0D
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BU of 2h0d by Molmil
Structure of a Bmi-1-Ring1B Polycomb group ubiquitin ligase complex
Descriptor: B lymphoma Mo-MLV insertion region, Ubiquitin ligase protein RING2, ZINC ION
Authors:Xu, R.M.
Deposit date:2006-05-14
Release date:2006-05-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a Bmi-1-Ring1B Polycomb Group Ubiquitin Ligase Complex.
J.Biol.Chem., 281, 2006
3UA4
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BU of 3ua4 by Molmil
Crystal Structure of Protein Arginine Methyltransferase PRMT5
Descriptor: GLYCEROL, Protein arginine N-methyltransferase 5
Authors:Sun, L, Wang, M, Lv, Z, Yang, N, Liu, Y, Bao, S, Gong, W, Xu, R.M.
Deposit date:2011-10-21
Release date:2011-12-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Structural insights into protein arginine symmetric dimethylation by PRMT5
Proc.Natl.Acad.Sci.USA, 108, 2011
8YJM
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BU of 8yjm by Molmil
Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and a single chain H2B-H2A chimera
Descriptor: DNA replication licensing factor MCM2, FACT complex subunit SPT16, Histone H2B 1/2/3/4/6,Histone H2A type 1-D, ...
Authors:Gan, S.L, Yang, W.S, Xu, R.M.
Deposit date:2024-03-02
Release date:2024-03-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (4.15 Å)
Cite:Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2.
Sci China Life Sci, 2024
8YJF
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BU of 8yjf by Molmil
Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and an H2A-H2B dimer
Descriptor: DNA replication licensing factor MCM2, FACT complex subunit SPT16, Histone H2A type 1-D, ...
Authors:Gan, S.L, Yang, W.S, Xu, R.M.
Deposit date:2024-03-01
Release date:2024-03-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2.
Sci China Life Sci, 2024
2GF7
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BU of 2gf7 by Molmil
Double tudor domain structure
Descriptor: Jumonji domain-containing protein 2A, SULFATE ION
Authors:Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M.
Deposit date:2006-03-21
Release date:2006-05-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
6LXD
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BU of 6lxd by Molmil
Pri-miRNA bound DROSHA-DGCR8 complex
Descriptor: Microprocessor complex subunit DGCR8, RNA (102-mer), Ribonuclease 3, ...
Authors:Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M.
Deposit date:2020-02-10
Release date:2020-04-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis for pri-miRNA Recognition by Drosha.
Mol.Cell, 78, 2020
5ZBA
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BU of 5zba by Molmil
Crystal structure of Rtt109-Asf1-H3-H4-CoA complex
Descriptor: COENZYME A, DNA damage response protein Rtt109, putative, ...
Authors:Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M.
Deposit date:2018-02-10
Release date:2018-07-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
5ZBB
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BU of 5zbb by Molmil
Crystal structure of Rtt109-Asf1-H3-H4 complex
Descriptor: DI(HYDROXYETHYL)ETHER, DNA damage response protein Rtt109, putative, ...
Authors:Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M.
Deposit date:2018-02-10
Release date:2018-07-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
5ZB9
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BU of 5zb9 by Molmil
Crystal structure of Rtt109 from Aspergillus fumigatus
Descriptor: DNA damage response protein Rtt109, putative, GLYCEROL
Authors:Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M.
Deposit date:2018-02-10
Release date:2018-07-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
2FHG
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BU of 2fhg by Molmil
Crystal Structure of Mycobacterial Tuberculosis Proteasome
Descriptor: 20S proteasome, alpha and beta subunits, proteasome, ...
Authors:Hu, G, Lin, G, Wang, M, Dick, L, Xu, R.M, Nathan, C, Li, H.
Deposit date:2005-12-23
Release date:2006-02-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate.
Mol.Microbiol., 59, 2006
5BTR
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BU of 5btr by Molmil
Crystal structure of SIRT1 in complex with resveratrol and an AMC-containing peptide
Descriptor: AMC-containing peptide, NAD-dependent protein deacetylase sirtuin-1, RESVERATROL, ...
Authors:Cao, D, Wang, M, Qiu, X, Liu, D, Jiang, H, Yang, N, Xu, R.M.
Deposit date:2015-06-03
Release date:2015-07-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol
Genes Dev., 29, 2015
7CQ2
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BU of 7cq2 by Molmil
Crystal structure of Slx1-Slx4
Descriptor: GLYCEROL, SLX4 isoform 1, Structure-specific endonuclease subunit SLX1, ...
Authors:Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M.
Deposit date:2020-08-08
Release date:2021-06-16
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex.
Nucleic Acids Res., 49, 2021
7CQ3
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BU of 7cq3 by Molmil
Crystal structure of Slx1-Slx4
Descriptor: SLX4 isoform 1, SULFATE ION, Structure-specific endonuclease subunit SLX1, ...
Authors:Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M.
Deposit date:2020-08-08
Release date:2021-06-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex.
Nucleic Acids Res., 49, 2021
7CQ4
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BU of 7cq4 by Molmil
Crystal structure of Slx1-Slx4 in complex with 5'flap DNA
Descriptor: DNA (27-MER), DNA (5'-D(*AP*GP*GP*AP*CP*AP*TP*CP*TP*TP*TP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*TP*AP*CP*AP*AP*CP*AP*GP*AP*T)-3'), ...
Authors:Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M.
Deposit date:2020-08-08
Release date:2021-06-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.294 Å)
Cite:Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex.
Nucleic Acids Res., 49, 2021
5H1L
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BU of 5h1l by Molmil
Crystal structure of WD40 repeat domains of Gemin5 in complex with 7-nt U4 snRNA fragment
Descriptor: GLYCEROL, Gem-associated protein 5, U4 snRNA (5'-R(*AP*UP*UP*UP*UP*UP*G)-3')
Authors:Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5H1K
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BU of 5h1k by Molmil
Crystal structure of WD40 repeat domains of Gemin5 in complex with 13-nt U4 snRNA fragment
Descriptor: Gem-associated protein 5, U4 snRNA (5'-R(*GP*CP*AP*AP*UP*UP*UP*UP*UP*GP*AP*CP*A)-3')
Authors:Wang, Y, Jin, W, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5H1M
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BU of 5h1m by Molmil
Crystal structure of WD40 repeat domains of Gemin5 in complex with M7G
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Gem-associated protein 5
Authors:Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.492 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5H1J
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BU of 5h1j by Molmil
Crystal structure of WD40 repeat domains of Gemin5
Descriptor: Gem-associated protein 5
Authors:Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
4HGA
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BU of 4hga by Molmil
Structure of the variant histone H3.3-H4 heterodimer in complex with its chaperone DAXX
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Liu, C.P, Xiong, C.Y, Wang, M.Z, Yu, Z.L, Yang, N, Chen, P, Zhang, Z.G, Li, G.H, Xu, R.M.
Deposit date:2012-10-07
Release date:2012-11-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Structure of the variant histone H3.3-H4 heterodimer in complex with its chaperone DAXX.
Nat.Struct.Mol.Biol., 19, 2012
6LXE
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BU of 6lxe by Molmil
DROSHA-DGCR8 complex
Descriptor: Microprocessor complex subunit DGCR8, Ribonuclease 3, ZINC ION
Authors:Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M.
Deposit date:2020-02-10
Release date:2020-04-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural Basis for pri-miRNA Recognition by Drosha.
Mol.Cell, 78, 2020
6INE
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BU of 6ine by Molmil
Crystal Structure of human ASH1L-MRG15 complex
Descriptor: GLYCEROL, Histone-lysine N-methyltransferase ASH1L, Mortality factor 4-like protein 1, ...
Authors:Hou, P, Huang, C, Liu, C.P, Yu, T, Yin, Y, Zhu, B, Xu, R.M.
Deposit date:2018-10-25
Release date:2019-03-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.
Structure, 27, 2019
6JN2
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BU of 6jn2 by Molmil
Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10
Descriptor: Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10
Authors:Song, X, Wang, M, Yang, N, Xu, R.M.
Deposit date:2019-03-13
Release date:2019-09-18
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6KN5
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BU of 6kn5 by Molmil
Crystal structure of AFF4 C-terminal domain
Descriptor: AF4/FMR2 family member 4
Authors:Chen, L.J, Yang, W.S, Xu, R.M.
Deposit date:2019-08-03
Release date:2020-07-08
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha.
Commun Biol, 3, 2020
8J6T
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BU of 8j6t by Molmil
Cryo-EM structure of the double CAF-1 bound right-handed Di-tetrasome
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, Z.Y, Xu, R.M.
Deposit date:2023-04-26
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023

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