6CRX
| SARS Spike Glycoprotein, Stabilized variant, two S1 CTDs in the upwards conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ... | Authors: | Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B. | Deposit date: | 2018-03-19 | Release date: | 2018-04-11 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis. Sci Rep, 8, 2018
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6CRW
| SARS Spike Glycoprotein, Stabilized variant, single upwards S1 CTD conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ... | Authors: | Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B. | Deposit date: | 2018-03-19 | Release date: | 2018-04-11 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis. Sci Rep, 8, 2018
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6U02
| CryoEM-derived model of NA-63 Fab in complex with N9 Shanghai2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab-63 Heavy Chain, Fab-63 Light Chain, ... | Authors: | Ward, A.B, Turner, H.L, Zhu, X. | Deposit date: | 2019-08-13 | Release date: | 2019-12-04 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host Microbe, 26, 2019
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7Z3A
| AMC009 SOSIPv5.2 in complex with Fabs ACS101 and ACS124 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACS101 heavy chain, ... | Authors: | van Schooten, J, Ward, A. | Deposit date: | 2022-03-02 | Release date: | 2022-08-10 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein. Nat Commun, 13, 2022
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7ZLK
| AMC009 SOSIPv5.2 in complex with Fabs ACS101 and ACS124 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACS114 heavy chain, ... | Authors: | van Schooten, J, Ozorowski, G, Ward, A. | Deposit date: | 2022-04-15 | Release date: | 2022-09-21 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer. Plos Pathog., 18, 2022
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7JN5
| Crystal structure of SARS-CoV receptor binding domain in complex with human antibody CR3022 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 heavy chain, ... | Authors: | Wu, N.C, Yuan, M, Zhu, X, Wilson, I.A. | Deposit date: | 2020-08-03 | Release date: | 2020-10-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.705 Å) | Cite: | A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody. Plos Pathog., 16, 2020
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8EQC
| Crystal structure of human anti-N1 neuraminidase 3H03 Fab | Descriptor: | 3H03 Fab heavy chain, 3H03 Fab light chain, PHOSPHATE ION | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2022-10-07 | Release date: | 2023-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56, 2023
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8EQA
| Crystal structure of human anti-N1 neuraminidase 2H08 Fab | Descriptor: | 2H08 Fab heavy chain, 2H08 Fab light chain, ZINC ION | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2022-10-07 | Release date: | 2023-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56, 2023
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6FYS
| Structure of single domain antibody SD83 | Descriptor: | 1,2-ETHANEDIOL, Single domain antibody SD83 | Authors: | Laursen, N.S, Wilson, I.A. | Deposit date: | 2018-03-12 | Release date: | 2018-11-07 | Last modified: | 2022-03-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science, 362, 2018
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5W9K
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5W9N
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5UMN
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5VZR
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5VYH
| Crystal Structure of MERS-CoV S1 N-terminal Domain | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ... | Authors: | Wang, N, Wrapp, D, Pallesen, J, Ward, A.B, McLellan, J.S. | Deposit date: | 2017-05-25 | Release date: | 2017-08-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5W9J
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5W9P
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5W9M
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5W9I
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5W9O
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5W9L
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5W9H
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7U04
| IOMA class antibody ACS101 | Descriptor: | GLYCEROL, IOMA class antibody ACS101 heavy chain, IOMA class antibody ACS101 light chain | Authors: | Farokhi, E, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2022-02-17 | Release date: | 2022-08-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein. Nat Commun, 13, 2022
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7U0K
| IOMA class antibody Fab ACS124 | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, IOMA Class antibody ACS124 Heavy chain, IOMA Class antibody ACS124 Light chain | Authors: | Farokhi, E, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2022-02-18 | Release date: | 2022-08-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein. Nat Commun, 13, 2022
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7U5G
| ACS122 Fab | Descriptor: | ACS122 Fab Heavy chain, ACS122 Fab Light chain | Authors: | Farokhi, E, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2022-03-02 | Release date: | 2022-11-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer. Plos Pathog., 18, 2022
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6OZ9
| Ebola virus glycoprotein in complex with EBOV-520 Fab | Descriptor: | EBOV-520 Fab heavy chain, EBOV-520 Fab light chain, Envelope glycoprotein, ... | Authors: | Milligan, J.C, Altman, P.X, Hui, S, Hastie, K.M, Gilchuk, P, Crowe, J.E, Saphire, E.O. | Deposit date: | 2019-05-15 | Release date: | 2020-03-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.462 Å) | Cite: | Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity, 52, 2020
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