7ZLK

AMC009 SOSIPv5.2 in complex with Fabs ACS101 and ACS124

Summary for 7ZLK

• Entry DOI: 10.2210/pdb7zlk/pdb
• EMDB information: 14783
• Descriptor: AMC009 SOSIPv5.2 envelope glycoprotein gp120, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• Functional Keywords: hiv-1, antibodies, silent face, gp120-gp41 interface, viral protein
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 16
• Total formula weight: 360729.83

Authors

van Schooten, J.,Ozorowski, G.,Ward, A. (deposition date: 2022-04-15, release date: 2022-09-21, Last modification date: 2022-11-30)

• Primary citation: van Schooten, J.,Schorcht, A.,Farokhi, E.,Umotoy, J.C.,Gao, H.,van den Kerkhof, T.L.G.M.,Dorning, J.,Rijkhold Meesters, T.G.,van der Woude, P.,Burger, J.A.,Bijl, T.,Ghalaiyini, R.,Torrents de la Pena, A.,Turner, H.L.,Labranche, C.C.,Stanfield, R.L.,Sok, D.,Schuitemaker, H.,Montefiori, D.C.,Burton, D.R.,Ozorowski, G.,Seaman, M.S.,Wilson, I.A.,Sanders, R.W.,Ward, A.B.,van Gils, M.J.; Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer.; Plos Pathog., 18:e1010945-e1010945, 2022; PubMed: 36395347; DOI: 10.1371/journal.ppat.1010945

Experimental method

ELECTRON MICROSCOPY (3.99 Å)