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7TZ9
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BU of 7tz9 by Molmil
Structure of PQS Response Protein PqsE(E182W) Variant
Descriptor: FE (III) ION, Quinolone signal response protein
Authors:Jeffrey, P.D, Taylor, I.R, Bassler, B.L.
Deposit date:2022-02-15
Release date:2022-08-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa.
Biochemistry, 61, 2022
7TZA
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BU of 7tza by Molmil
Structure of PQS Response Protein PqsE in complex with N-(4-(3-neopentylureido)phenyl)-1H-indazole-7-carboxamide
Descriptor: 1,2-ETHANEDIOL, FE (III) ION, N-{4-[(2,2-dimethylpropyl)carbamamido]phenyl}-1H-indazole-7-carboxamide, ...
Authors:Jeffrey, P.D, Taylor, I.R, Bassler, B.L.
Deposit date:2022-02-15
Release date:2022-08-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa.
Biochemistry, 61, 2022
7U6G
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BU of 7u6g by Molmil
Structure of PQS Response Protein PqsE(E182W,E280A) Variant
Descriptor: FE (III) ION, Quinolone signal response protein
Authors:Jeffrey, P.D, Taylor, I.R, Bassler, B.L.
Deposit date:2022-03-04
Release date:2022-08-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa.
Biochemistry, 61, 2022
7KGX
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BU of 7kgx by Molmil
Structure of PQS Response Protein PqsE in Complex with 4-(3-(2-methyl-2-morpholinobutyl)ureido)-N-(thiazol-2-yl)benzamide
Descriptor: 2-aminobenzoylacetyl-CoA thioesterase, 4-({[(2R)-2-methyl-2-(morpholin-4-yl)butyl]carbamoyl}amino)-N-(1,3-thiazol-2-yl)benzamide, FE (III) ION
Authors:Jeffrey, P.D, Taylor, I.R, Bassler, B.L.
Deposit date:2020-10-19
Release date:2021-05-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production.
Acs Chem.Biol., 16, 2021
7KGW
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BU of 7kgw by Molmil
Structure of PQS Response Protein PqsE in Complex N-(3-(1H-pyrazol-5-yl)phenyl)-1H-indazole-7-carboxamide
Descriptor: 2-aminobenzoylacetyl-CoA thioesterase, FE (III) ION, N-[3-(1H-pyrazol-3-yl)phenyl]-1H-indazole-7-carboxamide
Authors:Jeffrey, P.D, Taylor, I.R, Bassler, B.L.
Deposit date:2020-10-19
Release date:2021-05-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production.
Acs Chem.Biol., 16, 2021

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PDB entries from 2024-05-15

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