7B9F
| Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex | Descriptor: | EccB5, EccC5, EccD5, ... | Authors: | Chojnowski, G, Ritter, C, Beckham, K.S.H, Mullapudi, E, Rettel, M, Savitski, M.M, Mortensen, S.A, Ziemianowicz, D, Kosinski, J, Wilmanns, M. | Deposit date: | 2020-12-14 | Release date: | 2021-07-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the mycobacterial ESX-5 type VII secretion system pore complex. Sci Adv, 7, 2021
|
|
7B9S
| Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex | Descriptor: | EccB5, EccC5, EccD5, ... | Authors: | Chojnowski, G, Ritter, C, Beckham, K.S.H, Mullapudi, E, Rettel, M, Savitski, M.M, Mortensen, S.A, Ziemianowicz, D, Kosinski, J, Wilmanns, M. | Deposit date: | 2020-12-14 | Release date: | 2021-07-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the mycobacterial ESX-5 type VII secretion system pore complex. Sci Adv, 7, 2021
|
|
4AOF
| Selective small molecule inhibitor discovered by chemoproteomic assay platform reveals regulation of Th17 cell differentiation by PI3Kgamma | Descriptor: | N-[6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]ethanamide, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM | Authors: | Bergamini, G, Bell, K, Shimamura, S, Werner, T, Cansfield, A, Muller, K, Perrin, J, Rau, C, Ellard, K, Hopf, C, Doce, C, Leggate, D, Mangano, R, Mathieson, T, OMahony, A, Plavec, I, Rharbaoui, F, Reinhard, F, Savitski, M.M, Ramsden, N, Hirsch, E, Drewes, G, Rausch, O, Bantscheff, M, Neubauer, G. | Deposit date: | 2012-03-26 | Release date: | 2012-05-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A Selective Inhibitor Reveals Pi3Kgamma Dependence of T(H)17 Cell Differentiation. Nat.Chem.Biol., 8, 2012
|
|
7OZR
| |
8BSA
| Vc1313-LBD bound to D-arginine | Descriptor: | D-ARGININE, Methyl-accepting chemotaxis protein | Authors: | ter Beek, J, Berntsson, R.P.-A. | Deposit date: | 2022-11-24 | Release date: | 2023-06-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | D-amino acids signal a stress-dependent run-away response in Vibrio cholerae. Nat Microbiol, 8, 2023
|
|
8BSB
| Vc1313-LBD bound to D-lysine | Descriptor: | D-LYSINE, Methyl-accepting chemotaxis protein | Authors: | ter Beek, J, Berntsson, R.P.-A. | Deposit date: | 2022-11-24 | Release date: | 2023-06-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | D-amino acids signal a stress-dependent run-away response in Vibrio cholerae. Nat Microbiol, 8, 2023
|
|
4CFL
| N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH LY303511 | Descriptor: | 1,2-ETHANEDIOL, 8-phenyl-2-piperazin-1-yl-chromen-4-one, BRD4 PROTEIN, ... | Authors: | Chung, C, Dittmann, A, Drewes, G. | Deposit date: | 2013-11-18 | Release date: | 2014-01-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | The Commonly Used Pi3-Kinase Probe Ly294002 is an Inhibitor of Bet Bromodomains. Acs Chem.Biol., 9, 2014
|
|
4CFK
| N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH LY294002 | Descriptor: | 1,2-ETHANEDIOL, 2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE, BRD4 PROTEIN, ... | Authors: | Chung, C, Dittmann, A, Drewes, G. | Deposit date: | 2013-11-18 | Release date: | 2014-01-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The Commonly Used Pi3-Kinase Probe Ly294002 is an Inhibitor of Bet Bromodomains. Acs Chem.Biol., 9, 2014
|
|
6Y96
| solution structure of cold-shock domain 9 of drosophila Upstream of N-Ras (Unr) | Descriptor: | Upstream of N-ras, isoform A | Authors: | Sweetapple, L.J, Hollmann, N.M, Simon, B, Hennig, J. | Deposit date: | 2020-03-06 | Release date: | 2020-07-29 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Pseudo-RNA-Binding Domains Mediate RNA Structure Specificity in Upstream of N-Ras. Cell Rep, 32, 2020
|
|
6Y6E
| drosophila Unr CSD456 | Descriptor: | ETHYL MERCURY ION, Upstream of N-ras, isoform A | Authors: | Hollmann, N.M, Jagtap, P.K.A, Hennig, J. | Deposit date: | 2020-02-26 | Release date: | 2020-07-29 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Pseudo-RNA-Binding Domains Mediate RNA Structure Specificity in Upstream of N-Ras. Cell Rep, 32, 2020
|
|
6Y6M
| |
6Y4H
| |
7B7J
| |
3ZYU
| Crystal Structure of the first bromodomain of human BRD4 in complex with I-BET151(GSK1210151A) | Descriptor: | 1,2-ETHANEDIOL, 7-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-8-METHOXY-1-[(1R)-1-(PYRIDIN-2-YL)ETHYL]-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-2-ONE, BROMODOMAIN-CONTAINING PROTEIN 4 | Authors: | Chung, C.W, Mirguet, O. | Deposit date: | 2011-08-25 | Release date: | 2011-11-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Inhibition of Bet Recruitment to Chromatin as an Effective Treatment for Mll-Fusion Leukaemia. Nature, 478, 2011
|
|