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7ZGQ
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BU of 7zgq by Molmil
Polymerase module of yeast CPF in complex with the yPIM of Cft2
Descriptor: Cleavage factor two protein 2, Polyadenylation factor subunit 2, Protein CFT1, ...
Authors:Rodriguez-Molina, J.B, Passmore, L.A.
Deposit date:2022-04-04
Release date:2022-05-25
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Mol.Cell, 82, 2022
7ZGR
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BU of 7zgr by Molmil
Polymerase module of yeast CPF in complex with Mpe1, the yPIM of Cft2 and the pre-cleaved CYC1 RNA
Descriptor: Cleavage factor two protein 2, MPE1 isoform 1, Polyadenylation factor subunit 2, ...
Authors:Rodriguez-Molina, J.B, Passmore, L.A.
Deposit date:2022-04-04
Release date:2022-05-25
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Mol.Cell, 82, 2022
7ZGP
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BU of 7zgp by Molmil
Polymerase module of CPF in complex with Mpe1 and a pre-cleaved CYC1 RNA
Descriptor: MPE1 isoform 1, Polyadenylation factor subunit 2, Protein CFT1, ...
Authors:Rodriguez-Molina, J.B, Passmore, L.A.
Deposit date:2022-04-04
Release date:2022-05-25
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Mol.Cell, 82, 2022
6M8Q
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BU of 6m8q by Molmil
Cleavage and Polyadenylation Specificity Factor Subunit 3 (CPSF3) in complex with NVP-LTM531
Descriptor: Cleavage and polyadenylation specificity factor subunit 3, N-{3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzene-1-carbonyl}-L-phenylalanine, PHOSPHATE ION, ...
Authors:Weihofen, W.A, Salcius, M, Michaud, G.
Deposit date:2018-08-22
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Nat.Chem.Biol., 16, 2020
8A8F
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BU of 8a8f by Molmil
Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2
Descriptor: MANGANESE (II) ION, PHOSPHATE ION, RNA end formation protein 2, ...
Authors:Carminati, M, Manav, C.M, Bellini, D, Passmore, L.A.
Deposit date:2022-06-22
Release date:2023-11-29
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A direct interaction between CPF and RNA Pol II links RNA 3' end processing to transcription.
Mol.Cell, 83, 2023

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PDB entries from 2024-06-12

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