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7ZGP

Polymerase module of CPF in complex with Mpe1 and a pre-cleaved CYC1 RNA

Summary for 7ZGP
Entry DOI10.2210/pdb7zgp/pdb
EMDB information14710
DescriptorProtein CFT1, mRNA 3'-end-processing protein YTH1, Polyadenylation factor subunit 2, ... (6 entities in total)
Functional Keywordscpf, 3'-end processing, polya, rna binding protein
Biological sourceSaccharomyces cerevisiae (baker's yeast)
More
Total number of polymer chains5
Total formula weight294555.23
Authors
Rodriguez-Molina, J.B.,Passmore, L.A. (deposition date: 2022-04-04, release date: 2022-05-25, Last modification date: 2022-07-20)
Primary citationRodriguez-Molina, J.B.,O'Reilly, F.J.,Fagarasan, H.,Sheekey, E.,Maslen, S.,Skehel, J.M.,Rappsilber, J.,Passmore, L.A.
Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Mol.Cell, 82:2490-, 2022
Cited by
PubMed: 35584695
DOI: 10.1016/j.molcel.2022.04.021
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.7 Å)
Structure validation

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