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Crystal structure of human IRE1 cytoplasmic kinase-RNase region - complex with imidazopyridine compound 3
Descriptor:	2-methoxy-4-[6-(propan-2-ylamino)imidazo[1,2-b]pyridazin-3-yl]benzamide, SULFATE ION, Serine/threonine-protein kinase/endoribonuclease IRE1
Authors:	Joshi, A, Bayliss, R.
Deposit date:	2015-04-07
Release date:	2015-05-27
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	Molecular mechanisms of human IRE1 activation through dimerization and ligand binding. Oncotarget, 6, 2015

Crystal structure of human IRE1 cytoplasmic kinase-RNase region - apo
Descriptor:	SODIUM ION, Serine/threonine-protein kinase/endoribonuclease IRE1
Authors:	Bayliss, R, Joshi, A.
Deposit date:	2015-04-07
Release date:	2015-05-27
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Molecular mechanisms of human IRE1 activation through dimerization and ligand binding. Oncotarget, 6, 2015