6LBE
 
 | |
6LML
 | | Cryo-EM structure of the human glucagon receptor in complex with Gi1 | | Descriptor: | Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Qiao, A, Han, S, Li, X, Sun, F, Zhao, Q, Wu, B. | | Deposit date: | 2019-12-26 | | Release date: | 2020-04-01 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis of Gsand Girecognition by the human glucagon receptor.
Science, 367, 2020
|
|
6M4S
 | | Crystal Structure Analysis of the cytochrome P450 CYP-Sb21 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Cytochrome P450 hydroxylase sb21, ... | | Authors: | Li, F.W, Li, S.Y. | | Deposit date: | 2020-03-09 | | Release date: | 2021-02-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure-guided manipulation of the regioselectivity of the cyclosporine A hydroxylase CYP-sb21 from Sebekia benihana .
Synth Syst Biotechnol, 5, 2020
|
|
6JCJ
 | | Structure of crolibulin in complex with tubulin | | Descriptor: | (4R)-2,7,8-triamino-4-(3-bromo-4,5-dimethoxyphenyl)-4H-1-benzopyran-3-carbonitrile, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Zhang, Z, Yang, J. | | Deposit date: | 2019-01-29 | | Release date: | 2019-03-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design.
Biochem. Biophys. Res. Commun., 511, 2019
|
|
6ILG
 | |
6ILF
 | |
6ILE
 | | CRYSTAL STRUCTURE OF A MUTANT PTAL-N*01:01 FOR 2.9 ANGSTROM, 52M 53D 54L DELETED | | Descriptor: | Beta-2-microglobulin, HEV-1, MHC class I antigen | | Authors: | Qu, Z.H, Zhang, N.Z, Xia, C. | | Deposit date: | 2018-10-17 | | Release date: | 2019-07-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure and Peptidome of the Bat MHC Class I Molecule Reveal a Novel Mechanism Leading to High-Affinity Peptide Binding.
J Immunol., 202, 2019
|
|
1B8J
 | | ALKALINE PHOSPHATASE COMPLEXED WITH VANADATE | | Descriptor: | MAGNESIUM ION, PROTEIN (ALKALINE PHOSPHATASE), SULFATE ION, ... | | Authors: | Holtz, K.M, Stec, B, Kantrowitz, E.R. | | Deposit date: | 1999-02-01 | | Release date: | 1999-02-18 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A model of the transition state in the alkaline phosphatase reaction.
J.Biol.Chem., 274, 1999
|
|
7DLX
 | | crystal structure of H2AM4>Z-H2B | | Descriptor: | Histone H2B,Histone H2A | | Authors: | Dai, L.C, Zhou, Z. | | Deposit date: | 2020-11-30 | | Release date: | 2021-06-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.395 Å) | | Cite: | Recognition of the inherently unstable H2A nucleosome by Swc2 is a major determinant for unidirectional H2A.Z exchange.
Cell Rep, 35, 2021
|
|
6J20
 | | Crystal structure of the human NK1 substance P receptor | | Descriptor: | 5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one, Substance-P receptor,Endolysin | | Authors: | Chen, S, Lu, M, Zhang, H, Wu, B, Zhao, Q. | | Deposit date: | 2018-12-30 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography.
Nat Commun, 10, 2019
|
|
6ILC
 | |
6J21
 | | Crystal structure of the human NK1 substance P receptor | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one, Substance-P receptor,Endolysin | | Authors: | Chen, S, Lu, M, Zhang, H, Wu, B, Zhao, Q. | | Deposit date: | 2018-12-30 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography.
Nat Commun, 10, 2019
|
|
8WPK
 | | Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exgenous DNA | | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA polymerase, DNA polymerase processivity factor, ... | | Authors: | Wang, X, Li, N, Gao, N. | | Deposit date: | 2023-10-10 | | Release date: | 2023-11-29 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5.
Mol.Cell, 83, 2023
|
|
8WPE
 | | Structure of monkeypox virus polymerase complex F8-A22-E4-H5 (tag-free A22) with exogenous DNA | | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ... | | Authors: | Wang, X, Li, N, Gao, N. | | Deposit date: | 2023-10-10 | | Release date: | 2023-11-29 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5.
Mol.Cell, 83, 2023
|
|
8WPP
 | | Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with endogenous DNA | | Descriptor: | A22R DNA polymerase processivity factor, DNA polymerase, E4R Uracil-DNA glycosylase, ... | | Authors: | Wang, X, Li, N, Gao, N. | | Deposit date: | 2023-10-10 | | Release date: | 2023-11-29 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5.
Mol.Cell, 83, 2023
|
|
8WPF
 | | Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exogenous DNA bearing one abasic site | | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ... | | Authors: | Wang, X, Li, N, Gao, N. | | Deposit date: | 2023-10-10 | | Release date: | 2023-11-29 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5.
Mol.Cell, 83, 2023
|
|
2LP6
 | | Refined Solution NMR Structure of the 50S ribosomal protein L35Ae from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target (NESG) PfR48 | | Descriptor: | 50S ribosomal protein L35Ae | | Authors: | Snyder, D.A, Aramini, J.M, Yu, B, Huang, Y.J, Xiao, R, Cort, J.R, Shastry, R, Ma, L, Liu, J, Rost, B, Acton, T.B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-02-02 | | Release date: | 2012-02-15 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the ribosomal protein RP-L35Ae from Pyrococcus furiosus.
Proteins, 80, 2012
|
|
8HB2
 | |
8HBB
 | |
8HAZ
 | |
4FLP
 | | Crystal Structure of the first bromodomain of human BRDT in complex with the inhibitor JQ1 | | Descriptor: | (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, Bromodomain testis-specific protein, POTASSIUM ION | | Authors: | Filippakopoulos, P, Picaud, S, Qi, J, Felletar, I, Canning, P, Muniz, J, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Bradner, J, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2012-06-15 | | Release date: | 2012-07-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Small-Molecule Inhibition of BRDT for Male Contraception.
Cell(Cambridge,Mass.), 150, 2012
|
|
2JRT
 | | NMR solution structure of the protein coded by gene RHOS4_12090 of Rhodobacter sphaeroides. Northeast Structural Genomics target RhR5 | | Descriptor: | Uncharacterized protein | | Authors: | Wang, L, Chen, C, Nwosu, C, Cunningham, K, Owens, L, Ma, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-06-28 | | Release date: | 2007-08-21 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of the protein coded by gene RHOS4_12090 of Rhodobacter sphaeroides.
To be Published
|
|
7XV9
 | | Crystal structure of the Human TR4 DNA-Binding Domain | | Descriptor: | Nuclear receptor subfamily 2 group C member 2, ZINC ION | | Authors: | Liu, Y, Chen, Z. | | Deposit date: | 2022-05-21 | | Release date: | 2022-12-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.599 Å) | | Cite: | Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation.
Nucleic Acids Res., 51, 2023
|
|
7XV8
 | | Crystal structure of the Human TR4 DNA-Binding Domain Homodimer Bound to DR1 Response Element | | Descriptor: | DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*AP*GP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3'), Nuclear receptor subfamily 2 group C member 2, ... | | Authors: | Liu, Y, Chen, Z. | | Deposit date: | 2022-05-21 | | Release date: | 2022-12-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.199 Å) | | Cite: | Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation.
Nucleic Acids Res., 51, 2023
|
|
7XV6
 | |
