6NQT
 
 | | GalNac-T2 soaked with UDP-sugar | | Descriptor: | MANGANESE (II) ION, Polypeptide N-acetylgalactosaminyltransferase 2, [[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R},6~{R})-3-(hex-5-ynoylamino)-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl] hydrogen phosphate | | Authors: | Fernandez, D, Bertozzi, C.R, Schumann, B, Agbay, A. | | Deposit date: | 2019-01-21 | | Release date: | 2020-01-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells.
Mol.Cell, 78, 2020
|
|
6L08
 | |
7D2T
 | | Crystal structure of Rsu1/PINCH1_LIM45C complex | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, ... | | Authors: | Yang, H, Wei, Z, Yu, C. | | Deposit date: | 2020-09-17 | | Release date: | 2021-02-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
|
|
7D2S
 | | Crystal structure of Rsu1/PINCH1_LIM5C complex | | Descriptor: | GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, Ras suppressor protein 1, ... | | Authors: | Yang, H, Wei, Z, Cong, Y. | | Deposit date: | 2020-09-17 | | Release date: | 2021-02-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.653 Å) | | Cite: | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
|
|
7D2U
 | | Crystal structure of Rsu1/PINCH1_LIM45C complex | | Descriptor: | GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, MALONATE ION, ... | | Authors: | Yang, H, Wei, Z, Cong, Y. | | Deposit date: | 2020-09-17 | | Release date: | 2021-02-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
|
|
8FLG
 | | Bruton's tyrosine kinase in complex with an orthosteric inhibitor | | Descriptor: | DIMETHYL SULFOXIDE, N~2~-(3-chlorophenyl)-N-[(3R)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]glycinamide, Tyrosine-protein kinase BTK | | Authors: | Metrick, C.M, Marcotte, D.J. | | Deposit date: | 2022-12-21 | | Release date: | 2023-03-01 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Discovery of structural diverse reversible BTK inhibitors utilized to develop a novel in vivo CD69 and CD86 PK/PD mouse model.
Bioorg.Med.Chem.Lett., 80, 2023
|
|
8FLH
 | | Bruton's tyrosine kinase in complex with an orthosteric inhibitor | | Descriptor: | 2-(3,5-dichloroanilino)-1-{(3R)-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]azepan-1-yl}ethan-1-one, DIMETHYL SULFOXIDE, Tyrosine-protein kinase BTK | | Authors: | Metrick, C.M, Marcotte, D.J. | | Deposit date: | 2022-12-21 | | Release date: | 2023-03-01 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Discovery of structural diverse reversible BTK inhibitors utilized to develop a novel in vivo CD69 and CD86 PK/PD mouse model.
Bioorg.Med.Chem.Lett., 80, 2023
|
|
8FLV
 | | Bruton's tyrosine kinase in complex with compound 34 | | Descriptor: | 2-(3,5-dichloroanilino)-1-{(3R)-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}ethan-1-one, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | | Authors: | Metrick, C.M, Marcotte, D.J. | | Deposit date: | 2022-12-22 | | Release date: | 2023-04-05 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Discovery of structural diverse reversible BTK inhibitors utilized to develop a novel in vivo CD69 and CD86 PK/PD mouse model.
Bioorg.Med.Chem.Lett., 80, 2023
|
|
8IJ9
 | | Crystal structure of the ELKS1/Rab6B complex | | Descriptor: | ELKS/Rab6-interacting/CAST family member 1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Jin, G, Wei, Z. | | Deposit date: | 2023-02-26 | | Release date: | 2023-06-14 | | Last modified: | 2023-06-28 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structural basis of ELKS/Rab6B interaction and its role in vesicle capturing enhanced by liquid-liquid phase separation.
J.Biol.Chem., 299, 2023
|
|
7XOV
 | | Structural insights into human brain gut peptide cholecystokinin receptors | | Descriptor: | 2-[2-[[4-(4-chloranyl-2,5-dimethoxy-phenyl)-5-(2-cyclohexylethyl)-1,3-thiazol-2-yl]carbamoyl]-5,7-dimethyl-indol-1-yl]ethanoic acid, Cholecystokinin receptor type A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S. | | Deposit date: | 2022-05-01 | | Release date: | 2022-07-20 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into human brain-gut peptide cholecystokinin receptors.
Cell Discov, 8, 2022
|
|
7XOU
 | | Structural insights into human brain gut peptide cholecystokinin receptors | | Descriptor: | CCK-8, Cholecystokinin receptor type A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S. | | Deposit date: | 2022-05-01 | | Release date: | 2022-07-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into human brain-gut peptide cholecystokinin receptors.
Cell Discov, 8, 2022
|
|
7XOW
 | | Structural insights into human brain gut peptide cholecystokinin receptors | | Descriptor: | Gastrin, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S. | | Deposit date: | 2022-05-01 | | Release date: | 2022-07-20 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insights into human brain-gut peptide cholecystokinin receptors.
Cell Discov, 8, 2022
|
|
5ZYS
 | | Structure of Nephrin/MAGI1 complex | | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Nephrin | | Authors: | Weng, Z.F, Shng, Y, Zhu, J.W, Zhang, R.G. | | Deposit date: | 2018-05-28 | | Release date: | 2019-01-23 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling.
J. Am. Soc. Nephrol., 29, 2018
|
|
7E7L
 | | The crystal structure of arylacetate decarboxylase from Olsenella scatoligenes. | | Descriptor: | 4-HYDROXYPHENYLACETATE, Hydroxyphenylacetic acid decarboxylase | | Authors: | Lu, Q, Duan, Y, Zhang, Y, Yuchi, Z. | | Deposit date: | 2021-02-26 | | Release date: | 2021-07-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.53 Å) | | Cite: | The Glycyl Radical Enzyme Arylacetate Decarboxylase from Olsenella scatoligenes
Acs Catalysis, 11, 2021
|
|
7EEV
 | | Structure of UTP cyclohydrolase | | Descriptor: | DEOXYURIDINE-5'-TRIPHOSPHATE, GTP cyclohydrolase II, ZINC ION | | Authors: | Zhang, H, Zhang, Y, Yuchi, Z. | | Deposit date: | 2021-03-19 | | Release date: | 2021-07-28 | | Last modified: | 2022-09-21 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural and biochemical investigation of UTP cyclohydrolase
Acs Catalysis, 2021
|
|
7EJ3
 | | UTP cyclohydrolase | | Descriptor: | DIPHOSPHATE, GLYCINE, GTP cyclohydrolase II, ... | | Authors: | Zhang, H, Zhang, Y, Yuchi, Z. | | Deposit date: | 2021-04-01 | | Release date: | 2022-09-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural and biochemical investigation of UTP cyclohydrolase
Acs Catalysis, 2021
|
|
7FJ1
 | | Cryo-EM structure of pseudorabies virus C-capsid | | Descriptor: | Capsid vertex component 1, DNA packaging tegument protein UL25, Major capsid protein, ... | | Authors: | Zheng, Q, Li, S, Zha, Z, Sun, H. | | Deposit date: | 2021-08-02 | | Release date: | 2022-06-22 | | Method: | ELECTRON MICROSCOPY (4.43 Å) | | Cite: | Structures of pseudorabies virus capsids.
Nat Commun, 13, 2022
|
|
7FJ3
 | | Cryo-EM structure of PRV A-capid | | Descriptor: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | | Authors: | Zheng, Q, Li, S, Zha, Z, Sun, H. | | Deposit date: | 2021-08-02 | | Release date: | 2022-06-22 | | Method: | ELECTRON MICROSCOPY (4.53 Å) | | Cite: | Structures of pseudorabies virus capsids.
Nat Commun, 13, 2022
|
|
6J6P
 | | Crystal structure of diamondback moth ryanodine receptor phosphorylation domain(2836-3050) mutant S2946D | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... | | Authors: | Xu, T, Lin, L, Yuchi, Z. | | Deposit date: | 2019-01-15 | | Release date: | 2019-09-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Crystal structure of diamondback moth ryanodine receptor Repeat34 domain reveals insect-specific phosphorylation sites.
Bmc Biol., 17, 2019
|
|
6J6O
 | | Crystal structure of diamondback moth ryanodine receptor phosphorylation domain(2836-3050) | | Descriptor: | CHLORIDE ION, GLYCEROL, Ryanodine receptor, ... | | Authors: | Xu, T, Lin, L, Yuchi, Z. | | Deposit date: | 2019-01-15 | | Release date: | 2019-09-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.848 Å) | | Cite: | Crystal structure of diamondback moth ryanodine receptor Repeat34 domain reveals insect-specific phosphorylation sites.
Bmc Biol., 17, 2019
|
|
8IMS
 | | Crystal structure of TRAF7 coiled-coil domain | | Descriptor: | E3 ubiquitin-protein ligase TRAF7 | | Authors: | Hu, R, Lin, L, Lu, Q. | | Deposit date: | 2023-03-07 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development.
J Mol Cell Biol, 2024
|
|
