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6M2C
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BU of 6m2c by Molmil
Distinct mechanism of MUL1-RING domain simultaneously recruiting E2 enzyme and the substrate p53-TAD domain
Descriptor: Mitochondrial ubiquitin ligase activator of NFKB 1, Ubiquitin-conjugating enzyme E2 D2, ZINC ION
Authors:Lee, S.O, Ryu, K.S, Chi, S.-W.
Deposit date:2020-02-27
Release date:2021-04-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:MUL1-RING recruits the substrate, p53-TAD as a complex with UBE2D2-UB conjugate.
Febs J., 2022
6MYW
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BU of 6myw by Molmil
Gluconobacter Ene-Reductase (GluER) mutant - T36A
Descriptor: ACETATE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
Authors:Garfinkle, S.E, Jeffrey, P, Hyster, T.K.
Deposit date:2018-11-02
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.157 Å)
Cite:Photoexcitation of flavoenzymes enables a stereoselective radical cyclization.
Science, 364, 2019
6O08
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BU of 6o08 by Molmil
Gluconobacter Ene-Reductase (GluER)
Descriptor: ACETATE ION, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
Authors:Garfinkle, S.E, Jeffrey, P, Hyster, T.K.
Deposit date:2019-02-15
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Photoexcitation of flavoenzymes enables a stereoselective radical cyclization.
Science, 364, 2019
1O9A
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BU of 1o9a by Molmil
Solution structure of the complex of 1F12F1 from fibronectin with B3 from FnBB from S. dysgalactiae
Descriptor: FIBRONECTIN, FIBRONECTIN BINDING PROTEIN
Authors:Schwarz-Linek, U, Werner, J.M, Pickford, A.R, Pilka, E.S, Gurusiddappa, S, Briggs, J.A.G, Hook, M, Campbell, I.D, Potts, J.R.
Deposit date:2002-12-11
Release date:2003-05-08
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper.
Nature, 423, 2003
2MX0
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BU of 2mx0 by Molmil
Solution structure of HP0268 from Helicobacter pylori
Descriptor: Uncharacterized protein HP_0268
Authors:Lee, K.Y.
Deposit date:2014-12-05
Release date:2015-12-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure-based functional identification of Helicobacter pylori HP0268 as a nuclease with both DNA nicking and RNase activities
Nucleic Acids Res., 43, 2015
5F5R
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BU of 5f5r by Molmil
TRAP1N-ADPNP
Descriptor: Heat shock protein 75 kDa, mitochondrial, MAGNESIUM ION, ...
Authors:Tsai, F.T.F, Lee, S, Sung, N, Lee, J, Chang, C, Joachimiak, A.
Deposit date:2015-12-04
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HPH
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BU of 5hph by Molmil
Structure of TRAP1 fragment
Descriptor: GLYCEROL, Heat shock protein 75 kDa, mitochondrial, ...
Authors:Sung, N, Chang, C, Lee, S, Tsai, F.T.F.
Deposit date:2016-01-20
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.429 Å)
Cite:2.4 angstrom resolution crystal structure of human TRAP1NM, the Hsp90 paralog in the mitochondrial matrix.
Acta Crystallogr D Struct Biol, 72, 2016
5Y5U
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BU of 5y5u by Molmil
Crystal structures of spleen tyrosine kinase in complex with a novel inhibitor
Descriptor: 4-[(1-methylindazol-5-yl)amino]-2-(4-oxidanylpiperidin-1-yl)-8H-pyrido[4,3-d]pyrimidin-5-one, Tyrosine-protein kinase SYK
Authors:Lee, S.J, Lee, B.I.
Deposit date:2017-08-09
Release date:2018-06-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal Structures of Spleen Tyrosine Kinase in Complex with Two Novel 4-Aminopyrido[4,3-d] Pyrimidine Derivative Inhibitors.
Mol. Cells, 41, 2018
5Y5T
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BU of 5y5t by Molmil
Crystal structures of spleen tyrosine kinase in complex with a novel inhibitor
Descriptor: 2-[[(1S,2S)-2-azanylcyclohexyl]amino]-4-[(4-methylsulfonylphenyl)amino]-6H-pyrido[4,3-d]pyrimidin-5-one, Tyrosine-protein kinase SYK
Authors:Lee, S.J, Lee, B.I.
Deposit date:2017-08-09
Release date:2018-06-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Spleen Tyrosine Kinase in Complex with Two Novel 4-Aminopyrido[4,3-d] Pyrimidine Derivative Inhibitors.
Mol. Cells, 41, 2018

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