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4QXL
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BU of 4qxl by Molmil
Crystal Structure of FLHE
Descriptor: Flagellar protein flhE
Authors:Lee, J, Monzingo, A.F, Keatinge-Clay, A.T, Harshey, R.M.
Deposit date:2014-07-21
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.512 Å)
Cite:Structure of Salmonella FlhE, Conserved Member of a Flagellar Type III Secretion Operon.
J.Mol.Biol., 427, 2015
4TN0
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BU of 4tn0 by Molmil
Crystal Structure of the C-terminal Periplasmic Domain of Phosphoethanolamine Transferase EptC from Campylobacter jejuni
Descriptor: UPF0141 protein yjdB, ZINC ION
Authors:Fage, C.D, Brown, D, Boll, J.M, Keatinge-Clay, A.T, Trent, M.S.
Deposit date:2014-06-02
Release date:2014-10-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic study of the phosphoethanolamine transferase EptC required for polymyxin resistance and motility in Campylobacter jejuni.
Acta Crystallogr.,Sect.D, 70, 2014
4U3V
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BU of 4u3v by Molmil
Crystal structure of the trans-acyltransferase polyketide synthase enoyl-isomerase
Descriptor: Polyketide synthase PksR
Authors:Gay, D.C, Spear, P.J, Keatinge-Clay, A.T.
Deposit date:2014-07-22
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:A Double-Hotdog with a New Trick: Structure and Mechanism of the trans-Acyltransferase Polyketide Synthase Enoyl-isomerase.
Acs Chem.Biol., 9, 2014
3MJT
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BU of 3mjt by Molmil
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Descriptor: AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
Deposit date:2010-04-13
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
3MJS
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BU of 3mjs by Molmil
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Descriptor: (2S)-2-hydroxybutanedioic acid, AmphB, D-MALATE, ...
Authors:Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
Deposit date:2010-04-13
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
3MJC
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BU of 3mjc by Molmil
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Descriptor: AmphB, GLYCEROL
Authors:Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
Deposit date:2010-04-12
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
3MJV
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BU of 3mjv by Molmil
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Descriptor: AmphB, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
Deposit date:2010-04-13
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
3MJE
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BU of 3mje by Molmil
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Descriptor: AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
Deposit date:2010-04-12
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
4IMP
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BU of 4imp by Molmil
The missing linker: a dimerization motif located within polyketide synthase modules
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Polyketide synthase extender modules 3-4
Authors:Zheng, J, Keatinge-Clay, A.T.
Deposit date:2013-01-03
Release date:2013-03-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:The missing linker: a dimerization motif located within polyketide synthase modules.
Acs Chem.Biol., 8, 2013
4J1S
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BU of 4j1s by Molmil
Crystal structure of a ketoreductase domain from the bacillaene assembly line
Descriptor: Polyketide synthase PksJ
Authors:Zheng, J, Keatinge-Clay, A.T.
Deposit date:2013-02-01
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural and functional studies of a trans-acyltransferase polyketide assembly line enzyme that catalyzes stereoselective alpha- and beta-ketoreduction.
Proteins, 82, 2014
4J1Q
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BU of 4j1q by Molmil
Crystal structure of a ketoreductase domain from the bacillaene assembly line
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Polyketide synthase PksJ
Authors:Zheng, J, Keatinge-Clay, A.T.
Deposit date:2013-02-01
Release date:2014-03-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and functional studies of a trans-acyltransferase polyketide assembly line enzyme that catalyzes stereoselective alpha- and beta-ketoreduction.
Proteins, 82, 2014
4L4X
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BU of 4l4x by Molmil
An A2-type ketoreductase from a modular polyketide synthase
Descriptor: AmphI, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zheng, J, Keatinge-Clay, A.T.
Deposit date:2013-06-10
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Studies of an A2-Type Modular Polyketide Synthase Ketoreductase Reveal Features Controlling alpha-Substituent Stereochemistry.
Acs Chem.Biol., 8, 2013
4NA2
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BU of 4na2 by Molmil
Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase bound to its natural intermediate
Descriptor: Polyketide synthase PksJ
Authors:Gay, D.C, Gay, G.R, Keatinge-Clay, A.T.
Deposit date:2013-10-21
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase.
Structure, 22, 2014
4NA1
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BU of 4na1 by Molmil
Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase
Descriptor: Polyketide synthase PksJ, SULFATE ION
Authors:Gay, D.C, Gay, G.R, Keatinge-Clay, A.T.
Deposit date:2013-10-21
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase.
Structure, 22, 2014
4NA3
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BU of 4na3 by Molmil
Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase bound to a hexanoyl substrate mimic
Descriptor: Polyketide synthase PksJ, SULFATE ION
Authors:Gay, D.C, Gay, G.R, Keatinge-Clay, A.T.
Deposit date:2013-10-21
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase.
Structure, 22, 2014
5E5N
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BU of 5e5n by Molmil
Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 (C167S mutant, crystal form 1)
Descriptor: Polyketide synthase PksL
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T.
Deposit date:2015-10-08
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
5E6K
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BU of 5e6k by Molmil
Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 (C167S mutant, crystal form 2)
Descriptor: Polyketide synthase PksL, SULFATE ION
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T.
Deposit date:2015-10-10
Release date:2015-11-18
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
5ELP
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BU of 5elp by Molmil
Ketosynthase from module 1 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42
Descriptor: NRPS/PKS protein
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T, Zogzas, C.E.
Deposit date:2015-11-04
Release date:2016-01-13
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
5ERB
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BU of 5erb by Molmil
Ketosynthase from module 5 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42
Descriptor: Polyketide synthase
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T, Meinke, J.
Deposit date:2015-11-13
Release date:2015-12-23
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
5ENY
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BU of 5eny by Molmil
Ketosynthase from module 6 connected to acyl carrier protein from module 5 (unobservable) of the bacillaene synthase from Bacillus subtilis 168
Descriptor: Polyketide synthase PksL
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T.
Deposit date:2015-11-09
Release date:2015-12-23
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (4 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
5ERF
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BU of 5erf by Molmil
Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168
Descriptor: Polyketide synthase PksL
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T.
Deposit date:2015-11-14
Release date:2015-12-23
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
3EL6
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BU of 3el6 by Molmil
Crystal Structure of the Erythromycin Dehydratase
Descriptor: CHLORIDE ION, Erythromycin dehydratase, SULFATE ION
Authors:Keatinge-Clay, A.T.
Deposit date:2008-09-20
Release date:2008-11-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the erythromycin polyketide synthase dehydratase.
J.Mol.Biol., 384, 2008
1MZJ
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BU of 1mzj by Molmil
Crystal Structure of the Priming beta-Ketosynthase from the R1128 Polyketide Biosynthetic Pathway
Descriptor: ACETYL GROUP, Beta-ketoacylsynthase III, COENZYME A
Authors:Pan, H, Tsai, S.C, Meadows, E.S, Miercke, L.J.W, Keatinge-Clay, A, O'Connell, J, Khosla, C, Stroud, R.M.
Deposit date:2002-10-08
Release date:2002-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the priming beta-ketosynthase from the R1128 polyketide biosynthetic pathway
Structure, 10
7V6H
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BU of 7v6h by Molmil
Crystal Structure of the SpnL
Descriptor: Cyclopropane fatty-acyl-phospholipid synthase-like methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Wu, H.-H, Ko, T.-P, Liu, H.-W, Tsai, M.-D.
Deposit date:2021-08-20
Release date:2021-12-29
Method:X-RAY DIFFRACTION (3.054 Å)
Cite:Evidence for an Enzyme-Catalyzed Rauhut-Currier Reaction during the Biosynthesis of Spinosyn A.
J.Am.Chem.Soc., 143, 2021
4LEI
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BU of 4lei by Molmil
Spinosyn Forosaminyltransferase SpnP
Descriptor: NDP-forosamyltransferase, THYMIDINE-5'-DIPHOSPHATE
Authors:Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.K.
Deposit date:2013-06-25
Release date:2014-12-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural studies of the spinosyn forosaminyltransferase, SpnP.
Biochemistry, 53, 2014

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