1MZJ

Crystal Structure of the Priming beta-Ketosynthase from the R1128 Polyketide Biosynthetic Pathway

Summary for 1MZJ

• Entry DOI: 10.2210/pdb1mzj/pdb
• Related: 1EBL
• Descriptor: Beta-ketoacylsynthase III, COENZYME A, ACETYL GROUP, ... (4 entities in total)
• Functional Keywords: beta-ketosynthase, aromatic polyketide, biosynthetic engineering, catalytic triad, transferase
• Biological source: Streptomyces sp. R1128
• Cellular location: Cytoplasm (Probable): Q9F6D4
• Total number of polymer chains: 2
• Total formula weight: 72479.26

Authors

Pan, H.,Tsai, S.C.,Meadows, E.S.,Miercke, L.J.W.,Keatinge-Clay, A.,O'Connell, J.,Khosla, C.,Stroud, R.M. (deposition date: 2002-10-08, release date: 2002-12-11, Last modification date: 2011-07-13)

• Primary citation: Pan, H.,Tsai, S.,Meadows, E.S.,Miercke, L.J.,Keatinge-Clay, A.T.,O'Connell, J.,Khosla, C.,Stroud, R.M.; Crystal structure of the priming beta-ketosynthase from the R1128 polyketide biosynthetic pathway; Structure, 10:1559-1568, ; PubMed: 12429097; DOI: 10.1016/S0969-2126(02)00889-4

Experimental method

X-RAY DIFFRACTION (2.1 Å)