6A6F
 
 | | Crystal structure of Putative iron-sulfur cluster assembly scaffold protein for SUF system (FiSufU) from thermophilic Fervidobacterium Islandicum AW-1 | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Iron-sulfur cluster assembly scaffold protein NifU, ... | | Authors: | Dhanasingh, I, Jin, H.S, Lee, D.W, Lee, S.H. | | Deposit date: | 2018-06-27 | | Release date: | 2019-10-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The sulfur formation system mediating extracellular cysteine-cystine recycling in Fervidobacterium islandicum AW-1 is associated with keratin degradation.
Microb Biotechnol, 2020
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8HBE
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8HBF
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8HBH
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7D4P
 | | Structure of human TRPC5 in complex with clemizole | | Descriptor: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole, ... | | Authors: | Chen, L, Song, K, Wei, M, Guo, W. | | Deposit date: | 2020-09-24 | | Release date: | 2021-03-31 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural basis for human TRPC5 channel inhibition by two distinct inhibitors.
Elife, 10, 2021
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7D4Q
 | | Structure of human TRPC5 in complex with HC-070 | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 8-(3-chloranylphenoxy)-7-[(4-chlorophenyl)methyl]-3-methyl-1-(3-oxidanylpropyl)purine-2,6-dione, CALCIUM ION, ... | | Authors: | Chen, L, Song, K, Wei, M, Guo, W. | | Deposit date: | 2020-09-24 | | Release date: | 2021-03-31 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (2.74 Å) | | Cite: | Structural basis for human TRPC5 channel inhibition by two distinct inhibitors.
Elife, 10, 2021
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7E4T
 | | Human TRPC5 apo state structure at 3 angstrom | | Descriptor: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, ... | | Authors: | Chen, L, Song, K, Wei, M, Guo, W. | | Deposit date: | 2021-02-15 | | Release date: | 2021-03-31 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis for human TRPC5 channel inhibition by two distinct inhibitors.
Elife, 10, 2021
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7DXC
 | | Structure of TRPC3 at 3.06 angstrom in low calcium state | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL HEMISUCCINATE, Short transient receptor potential channel 3, ... | | Authors: | Chen, L, Guo, W. | | Deposit date: | 2021-01-18 | | Release date: | 2022-02-02 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
Neuron, 110, 2022
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7DXB
 | | Structure of TRPC3 at 2.7 angstrom in high calcium state | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Chen, L, Guo, W. | | Deposit date: | 2021-01-18 | | Release date: | 2022-02-02 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
Neuron, 110, 2022
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7DXD
 | | Structure of TRPC3 at 3.9 angstrom in 1340 nM free calcium state | | Descriptor: | CALCIUM ION, CHOLESTEROL HEMISUCCINATE, Short transient receptor potential channel 3, ... | | Authors: | Chen, L, Guo, W. | | Deposit date: | 2021-01-18 | | Release date: | 2022-01-19 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
Neuron, 110, 2022
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7DXG
 | | Structure of SAR7334-bound TRPC6 at 2.9 angstrom | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[[(1R,2R)-2-[(3R)-3-azanylpiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloranyl-benzenecarbonitrile, CALCIUM ION, ... | | Authors: | Chen, L, Guo, W. | | Deposit date: | 2021-01-18 | | Release date: | 2022-02-02 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
Neuron, 110, 2022
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7DXF
 | | Structure of BTDM-bound human TRPC6 nanodisc at 2.9 angstrom in high calcium state | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Chen, L, Guo, W. | | Deposit date: | 2021-01-18 | | Release date: | 2022-02-02 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
Neuron, 110, 2022
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7DXE
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6L48
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6L47
 | | Structure of the human sterol O-acyltransferase 1 in complex with CI-976 | | Descriptor: | 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide, CHOLESTEROL, Sterol O-acyltransferase 1 | | Authors: | Chen, L, Guan, C, Niu, Y. | | Deposit date: | 2019-10-16 | | Release date: | 2020-04-29 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor.
Nat Commun, 11, 2020
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5YKF
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5YKG
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5YKE
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5YWC
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5YW9
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5YWB
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5YW8
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5YWD
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5YW7
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5YWA
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