5YKE
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A)
Summary for 5YKE
Entry DOI | 10.2210/pdb5yke/pdb |
EMDB information | 6689 6831 8470 |
Descriptor | ATP-sensitive inward rectifier potassium channel 11, ATP-binding cassette sub-family C member 8 isoform X2, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide (3 entities in total) |
Functional Keywords | katp, channel, glibenclamide, sulfonylurea, membrane protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 8 |
Total formula weight | 885621.02 |
Authors | |
Primary citation | Wu, J.X.,Ding, D.,Wang, M.,Kang, Y.,Zeng, X.,Chen, L. Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9:553-567, 2018 Cited by PubMed: 29594720DOI: 10.1007/s13238-018-0530-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.11 Å) |
Structure validation
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