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7QXR
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BU of 7qxr by Molmil
Azacoelenterazine-bound Renilla-type luciferase (AncFT)
Descriptor: 3-(4-hydroxyphenyl)-8-[(4-hydroxyphenyl)methyl]-5-(phenylmethyl)-1$l^{4},4,7,8-tetrazabicyclo[4.3.0]nona-1(6),2,4-trien-9-one, Fragment transplantation onto a hyperstable ancestor of haloalkane dehalogenases and Renilla luciferase (Anc-FT)
Authors:Marek, M, Schenkmayerova, A, Janin, Y.L.
Deposit date:2022-01-27
Release date:2022-12-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:Catalytic mechanism for Renilla-type luciferases
Nat Catal, 2023
7OMD
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BU of 7omd by Molmil
Crystal structure of azacoelenterazine-bound Renilla reniformis luciferase variant RLuc8-D162A
Descriptor: 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one, CHLORIDE ION, Coelenterazine h 2-monooxygenase, ...
Authors:Schenkmayerova, A, Janin, Y.L, Marek, M.
Deposit date:2021-05-21
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Catalytic mechanism for Renilla-type luciferases
Nat Catal, 2023
8BO9
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BU of 8bo9 by Molmil
NanoLuc-D9R/H57A/K89R mutant complexed with azacoelenterazine bound in intra-barrel catalytic site
Descriptor: 3-(4-hydroxyphenyl)-8-[(4-hydroxyphenyl)methyl]-5-(phenylmethyl)-1$l^{4},4,7,8-tetrazabicyclo[4.3.0]nona-1(6),2,4-trien-9-one, Non structural polyprotein
Authors:Marek, M, Janin, L.Y.
Deposit date:2022-11-15
Release date:2023-09-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.
Nat Commun, 14, 2023
7QXQ
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BU of 7qxq by Molmil
Coelenteramide-bound Renilla-type luciferase (AncFT)
Descriptor: Fragment transplantation onto hyperstable ancestor of haloalkane dehalogenases and Renilla luciferase (Anc-FT), N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE
Authors:Marek, M, Schenkmayerova, A.
Deposit date:2022-01-27
Release date:2022-12-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Catalytic mechanism for Renilla-type luciferases
Nat Catal, 2023
7OME
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BU of 7ome by Molmil
Azacoelenterazine-bound Renilla-type engineered ancestral luciferase variant (AncFT7)
Descriptor: 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one, Renilla-type engineered ancestral luciferase variant (AncFT7)
Authors:Schenkmayerova, A, Janin, Y.L, Marek, M.
Deposit date:2021-05-21
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Structural and chemical basis of the Renilla-type bioluminescence
To Be Published
7OMR
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BU of 7omr by Molmil
Crystal structure of coelenteramide-bound Renilla reniformis luciferase RLuc8-D162A variant
Descriptor: Coelenterazine h 2-monooxygenase, GLYCEROL, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE
Authors:Schenkmayerova, A, Marek, M.
Deposit date:2021-05-24
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Catalytic mechanism for Renilla-type luciferases
Nat Catal, 2023
7OMO
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BU of 7omo by Molmil
Crystal structure of coelenteramine-bound Renilla reniformis luciferase RLuc8-D120A variant
Descriptor: 4-[5-azanyl-6-(phenylmethyl)pyrazin-2-yl]phenol, CHLORIDE ION, GLYCEROL, ...
Authors:Schenkmayerova, A, Marek, M.
Deposit date:2021-05-24
Release date:2022-06-01
Last modified:2023-01-18
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Catalytic mechanism for Renilla-type luciferases
Nat Catal, 2023
8AQH
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BU of 8aqh by Molmil
NanoLuc-Y94A luciferase mutant
Descriptor: NanoLuc luciferase
Authors:Nemergut, M, Marek, M.
Deposit date:2022-08-12
Release date:2023-08-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.
Nat Commun, 14, 2023
8AQ6
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BU of 8aq6 by Molmil
NanoLuc luciferase with bound furimamide in surface allosteric site
Descriptor: CHLORIDE ION, GLYCEROL, N-(3-Benzyl-5-phenylpyrazin-2-yl)-2-(furan-2-yl)acetamide, ...
Authors:Nemergut, M, Marek, M.
Deposit date:2022-08-11
Release date:2023-08-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.
Nat Commun, 14, 2023
8AQI
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BU of 8aqi by Molmil
NanoLuc luciferase with bound coelenteramide in surface allosteric site
Descriptor: CHLORIDE ION, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, NanoLuc luciferase, ...
Authors:Nemergut, M, Marek, M.
Deposit date:2022-08-12
Release date:2023-08-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.
Nat Commun, 14, 2023

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