8AQI

NanoLuc luciferase with bound coelenteramide in surface allosteric site

Summary for 8AQI

• Entry DOI: 10.2210/pdb8aqi/pdb
• Descriptor: NanoLuc luciferase, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: luciferase, nanoluc, nluc, luciferin, coelenterazine, luminescent protein
• Biological source: Oplophorus gracilirostris
• Total number of polymer chains: 8
• Total formula weight: 165051.30

Authors

Nemergut, M.,Marek, M. (deposition date: 2022-08-12, release date: 2023-08-23, Last modification date: 2023-12-27)

• Primary citation: Nemergut, M.,Pluskal, D.,Horackova, J.,Sustrova, T.,Tulis, J.,Barta, T.,Baatallah, R.,Gagnot, G.,Novakova, V.,Majerova, M.,Sedlackova, K.,Marques, S.M.,Toul, M.,Damborsky, J.,Prokop, Z.,Bednar, D.,Janin, Y.L.,Marek, M.; Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.; Nat Commun, 14:7864-7864, 2023; PubMed: 38030625; DOI: 10.1038/s41467-023-43403-y

Experimental method

X-RAY DIFFRACTION (1.99 Å)